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Associating white matter microstructural integrity and improvements in reactive step** in people with Parkinson’s Disease
Reactive steps are rapid responses after balance challenges. People with Parkinson's Disease (PwPD) demonstrate impaired reactive step**,...
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The relationship between blast-related mild traumatic brain injury and executive function is moderated by white matter integrity
Blast-related mild traumatic brain injury (BR mTBI) is a critical research area in recent combat veterans due to increased prevalence of survived...
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β1 integrins play a critical role maintaining vascular integrity in the hypoxic spinal cord, particularly in white matter
Interactions between extracellular matrix (ECM) proteins and β1 integrins play an essential role maintaining vascular integrity in the brain,...
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Correlation of Immune-Inflammatory Response System (IRS)/Compensatory Immune-Regulatory Reflex System (CIRS) with White Matter Integrity in First-Episode Patients with Schizophrenia
Several studies have reported compromised white matter integrity, and that some inflammatory mediators may underlie this functional dysconnectivity...
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White matter integrity is associated with cognition and amyloid burden in older adult Koreans along the Alzheimer’s disease continuum
BackgroundWhite matter (WM) microstructural changes in the hippocampal cingulum bundle (CBH) in Alzheimer’s disease (AD) have been described in...
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ASK1-K716R reduces neuroinflammation and white matter injury via preserving blood–brain barrier integrity after traumatic brain injury
BackgroundTraumatic brain injury (TBI) is a significant worldwide public health concern that necessitates attention. Apoptosis signal-regulating...
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Association between the Pittsburgh sleep quality index and white matter integrity in healthy adults: a whole-brain magnetic resonance imaging study
To disclose possible associations between poorer sleep quality and structural brain alterations in a non-psychiatric healthy population, this study...
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Prenatal depression exposure alters white matter integrity and neurodevelopment in early childhood
Prenatal exposure to maternal depression increases the risk for onset of emotional and behavioral disorders in children. We investigated the effects...
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Having a stimulating lifestyle is associated with maintenance of white matter integrity with age
Brain maintenance refers to the fact that some older adults experience few age-related changes in the brain, which helps maintain their cognition....
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Correlation between White Matter Changes and Clinical Symptoms in Patients with Major Depressive Disorder
AbstractTo analyse the structural characteristics and fibre integrity of white matter in patients with major depressive disorder (MDD) and its...
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More organized white matter is associated with positivity bias in older adults
On average, healthy older adults prefer positive over neutral or negative stimuli. This positivity bias is related to memory and attention processes...
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Modulation of the proteoglycan receptor PTPσ promotes white matter integrity and functional recovery after intracerebral hemorrhage stroke in mice
BackgroundIntracerebral hemorrhage (ICH) is associated with high morbidity and mortality rates. However, extant investigations have mainly focused on...
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Influences of amyloid-β and tau on white matter neurite alterations in dementia with Lewy bodies
Dementia with Lewy bodies (DLB) is a neurodegenerative condition often co-occurring with Alzheimer’s disease (AD) pathology. Characterizing white...
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Changes in cardiovascular health and white matter integrity with aerobic exercise, cognitive and combined training in physically inactive healthy late-middle-aged adults: the “Projecte Moviment” randomized controlled trial
IntroductionThis is a 12-weeks randomized controlled trial examining the effects of aerobic exercise (AE), computerized cognitive training (CCT) and...
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White matter changes in Parkinson’s disease
Parkinson’s disease (PD) is the second most common neurodegenerative disease after Alzheimer’s disease (AD). It is characterized by a progressive...
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Microglia-specific deletion of histone deacetylase 3 promotes inflammation resolution, white matter integrity, and functional recovery in a mouse model of traumatic brain injury
BackgroundHistone deacetylases (HDACs) are believed to exacerbate traumatic brain injury (TBI) based on studies using pan-HDAC inhibitors. However,...
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Association between hypertension and neurovascular inflammation in both normal-appearing white matter and white matter hyperintensities
The major vascular cause of dementia is cerebral small vessel disease (SVD), including white matter hyperintensities (WMH) amongst others. While the...
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White matter associations with spelling performance
Multiple neurocognitive processes are involved in the highly complex task of producing written words. Yet, little is known about the neural pathways...
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Asymmetric alterations of white matter integrity in patients with insomnia disorder
Despite the adverse consequences of insomnia disorder for both individuals and society, the underlying neurobiological processes are poorly...
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White matter microstructure of children with sensory over-responsivity is associated with affective behavior
BackgroundSensory processing dysfunction (SPD) is linked to altered white matter (WM) microstructure in school-age children. Sensory...
