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Virus Entry Inhibitors Stop** the Enemy at the Gate
This book focuses on the important discoveries of the small molecule-, peptide-, and protein-based virus entry inhibitors and discusses advance...
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Influenza A Virus: Cellular Entry
The frequent emergence of pathogenic viruses with pandemic potential has posed a significant threat to human health and economy, despite enormous...
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Influenza Virus Entry inhibitors
Influenza is a major challenge to health and the global economy. However, the increasing emergence of drug resistance during influenza pandemics...
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Role of angiotensin II in cellular entry and replication of dengue virus
Previous studies have demonstrated the relevance of several soluble molecules in the pathogenesis of dengue. In this regard, a possible role for...
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A Quantitative Fusion Assay to Study Measles Virus Entry
We have adopted a real-time assay based on a dual-split reporter to assess cell-cell fusion mediated by the measles virus (MeV) membrane fusion...
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Single-Particle Tracking of Virus Entry in Live Cells
Novel imaging technologies such as single-particle tracking provide tools to study the intricate process of virus infection in host cells. In this...
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Ebola Virus Entry Inhibitors
Ebola virus (EBOV) is one of the most deadliest agents already known, causing periodic epidemic of a severe hemorrhagic fever disease in Africa....
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Virus Entry Inhibitors: Past, Present, and Future
The approval of enfuvirtide marked a milestone for the development of virus entry inhibitor-based antiviral therapeutics. Since then, more peptide-,...
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Entry Inhibitors of Hepatitis C Virus
Hepatitis C virus (HCV) infection affects approximately 1% of the world’s population and is a major cause of chronic liver diseases. Although...
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Virus Infected Cells
Virus-infected Cells is a comprehensive and technical exploration of the intricate interactions between viruses and host cells. This book delves into...
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Lessons in self-defence: inhibition of virus entry by intrinsic immunity
Virus entry, consisting of attachment to and penetration into the host target cell, is the first step of the virus life cycle and is a critical ‘do...
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Development of an effective single-chain variable fragment recognizing a novel epitope in the hepatitis C virus E2 protein that restricts virus entry into hepatocytes
Previously, we reported a neutralizing monoclonal antibody, A8A11, raised against a novel conserved epitope within the hepatitis C virus (HCV) E2...
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Broad-spectrum Respiratory Virus Entry Inhibitors
With the increasing global human population, travel, and socioeconomic activities, more and more novel pathogenic viruses will emerge or re-emerge....
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Flavivirus Entry Inhibitors
Flaviviruses, including Dengue virus, Zika virus, Yellow fever virus, Japanese encephalitis virus, West Nile virus, cause thousands of deaths and...
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Pseudotyped Virus for Henipavirus
The genus Henipavirus (HNV) includes two virulent infectious viruses, Nipah virus (NiV) and Hendra virus (HeV), which are the focus of considerable...
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Coronavirus Entry Inhibitors
Coronaviruses (CoVs) are enveloped RNA viruses that widely exist in the environment. Several CoVs possess a strong ability to infect humans, termed...
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Seed transmission of raspberry bushy dwarf virus is blocked in Nicotiana benthamiana plants by preventing virus entry into the embryo from the infected embryo sac and endosperm
Raspberry bushy dwarf virus (RBDV) is transmitted through seed in infected red raspberry plants after pollination with pollen grains from healthy red...
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Introduction to West Nile Virus
West Nile virus (WNV) is a mosquito-borne, single-stranded, positive-sense RNA virus belonging to the Flaviviridae family. After WNV gains entry...
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Pseudotyped Virus for Flaviviridae
Members of Flaviviridae are enveloped single positive-stranded RNA viruses including hepacivirus, pestivirus, pegivirus, and mosquito-transmitted...
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Biology of Variola Virus
Variola virusVariola virus is an anthroponotic agent that belongs to the orthopoxvirus family. It is an etiological agent of smallpoxSmallpox, an...