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Viral and host mediators of non-suppressible HIV-1 viremia
Non-suppressible HIV-1 viremia (NSV) is defined as persistent low-level viremia on antiretroviral therapy (ART) without evidence of ART non-adherence...
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The kinetics of SARS-CoV-2 viremia in COVID-19 patients receiving remdesivir
Detection of SARS-CoV-2 RNA in serum, viremia, has been linked to disease severity and outcome. The kinetics of viremia in patients receiving...
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HIV viremia contributes to neurocognitive impairments in persons who use cocaine
Persons with HIV (PWH) who use illicit drugs are at elevated risk for neurocognitive impairment (NCI). This study investigated the effects of HIV...
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Recurrent parvovirus B19 viremia resulting in two episodes of hemophagocytic lymphohistiocytosis
BackgroundHemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory condition with uncontrolled activation of lymphocytes and macrophages....
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A Cell Membrane Fusion Assay for the Fish Pathogen Spring Viremia of Carp Virus (SVCV)
Fusion of the infected cell membranes is a characteristic effect of a wide number of viral infections. Spring viremia of carp virus (SVCV), a...
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A recombinant measles virus vaccine strongly reduces SHIV viremia and virus reservoir establishment in macaques
Replicative vectors derived from live-attenuated measles virus (MV) carrying additional non-measles vaccine antigens have long demonstrated safety...
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Gut microbiome signatures linked to HIV-1 reservoir size and viremia control
BackgroundThe potential role of the gut microbiome as a predictor of immune-mediated HIV-1 control in the absence of antiretroviral therapy (ART) is...
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Correlation between low-level viremia and hepatitis B-related hepatocellular carcinoma and recurrence: a retrospective study
BackgroundLow-level viremia generally refers to detectable HBV DNA levels lower than 2000 IU/mL. Studies show that low-level viremia is a risk factor...
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Hepatitis B relapse after entecavir or tenofovir alafenamide cessation under anti-viral prophylaxis for cancer chemotherapy
BackgroundNo study has comparing hepatitis B virus (HBV) relapse rates among patients with both cancer and hepatitis B e antigen (HBeAg)-negative...
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Mechanisms of Tick-Borne Virus Transmission
The simplistic concept of an arbovirus is one centered around viremia: an infected vertebrate host with sufficient virus circulating in its blood to...
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Immune response induced by standard and fractional doses of 17DD yellow fever vaccine
The re-emergence of yellow fever (YF) urged new mass vaccination campaigns and, in 2017, the World Health Organization approved the use of the...
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Neutralizing antibodies targeting a novel epitope on envelope protein exhibited broad protection against flavivirus without risk of disease enhancement
BackgroundFlavivirus causes many serious public health problems worldwide. However, licensed DENV vaccine has restrictions on its use, and there is...
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High prevalence and viremia of human pegivirus 2 in the HIV-infected population in Honghe Prefecture, Yunnan Province
Human pegivirus 2 (HPgV-2) is a recently recognized pegivirus of the family Flaviviridae. To investigate the epidemic features of HPgV-2 circulating...
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Immune reconstitution inflammatory syndrome drives emergence of HIV drug resistance from multiple anatomic compartments in a person living with HIV
Reservoirs of HIV maintained in anatomic compartments during antiretroviral therapy prevent HIV eradication. However, mechanisms driving their...
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Determining host factors contributing to the reactivation of JC virus in kidney transplant recipients
Background and aimsThe John Cunningham virus (JCV) is the established etiological agent of the polyomavirus-associated nephropathy among renal...
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AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques
The main barrier to HIV cure is a persistent reservoir of latently infected CD4 + T cells harboring replication-competent provirus that fuels rebound...
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MVA-based vaccines are protective against lethal eastern equine encephalitis virus aerosol challenge in cynomolgus macaques
MVA-based monovalent eastern equine encephalitis virus (MVA-BN-EEEV) and multivalent western, eastern, and Venezuelan equine encephalitis virus...
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Dynamics and durability of HIV-1 neutralization are determined by viral replication
Human immunodeficiency virus type 1 (HIV-1)-neutralizing antibodies (nAbs) that prevent infection are the main goal of HIV vaccine discovery. But as...
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A replicating RNA vaccine confers protection in a rhesus macaque model of Crimean-Congo hemorrhagic fever
Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne febrile illness with a wide geographic distribution. In recent years the geographic range of...
