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Facial nerve regeneration using silicone conduits filled with ammonia-functionalized graphene oxide and frankincense-embedded hydrogel
BackgroundSilicone tube (ST) conduits have been accepted as a therapeutic alternative to direct nerve suturing in the treatment of nerve injuries;...
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Transcriptome Analysis Reveals Dynamic Microglial-Induced A1 Astrocyte Reactivity via C3/C3aR/NF-κB Signaling After Ischemic Stroke
Microglia and astrocytes are key players in neuroinflammation and ischemic stroke. A1 astrocytes are a subtype of astrocytes that are extremely...
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Sensory Systems of the African Naked Mole-Rat
Naked mole-rats share some sensory characteristics with other subterraneans, including lack of object vision, retention of the ability to entrain...
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Experience-dependent plasticity in early stations of sensory processing in mature brains: effects of environmental enrichment on dendrite measures in trigeminal nuclei
Nervous systems respond with structural changes to environmental changes even in adulthood. In recent years, experience-dependent structural...
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Partial blood replacement ameliorates middle cerebral artery occlusion generated neurological aberrations by intervening TLR4 and NLRP3 cascades in rats
Acute ischemic stroke is a catastrophic medical condition that causes severe disability and mortality if the sufferer escapes treatment within a...
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Optimizing intraluminal monofilament model of ischemic stroke in middle-aged Sprague–Dawley rats
Intraluminal monofilament model of middle cerebral artery occlusion (MCAO) is widely adopted for ischemic stroke; and Sprague–Dawley (SD) rats are...
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Alloparental Care and Postnatal Development of Heterozygous TPH2 Transgenic Mice
AbstractThe issue of the relationship between the transmission of a negative effect from a depressed mother to her offspring is one of the priorities...
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Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth
Polyunsaturated fatty acids (PUFAs) are used as traditional remedies to treat hair loss, but the mechanisms underlying their beneficial effects are...
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The aging ovary impairs acute stroke outcomes
In experimental stroke, ovariectomized (OVX) adult rats have larger infarct volumes and greater sensory-motor impairment as compared to ovary-intact...
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Pharmaco-toxicological effects of the novel tryptamine hallucinogen 5-MeO-MiPT on motor, sensorimotor, physiological, and cardiorespiratory parameters in mice—from a human poisoning case to the preclinical evidence
RationaleThe 5-methoxy-N-methyl-N-isopropyltryptamine (5-MeO-MiPT, known online as “Moxy”) is a new psychedelic tryptamine first identified on...
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More Than the Sum of Its Parts: Visual–Tactile Integration in the Behaving Rat
We experience the world by constantly integrating cues from multiple modalities to form unified sensory percepts. Once familiar with multimodal...
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Alteplase Improves Neurological Function and Affects Expression of SDF-1 and Claudin-5 in Rats with Acute Cerebral Infarction
AbstractWe aimed to explore the effects of alteplase on neurological function and expression of stromal cell-derived factor-1 (SDF-1) and Claudin-5...
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MAM-2201 acute administration impairs motor, sensorimotor, prepulse inhibition, and memory functions in mice: a comparison with its analogue AM-2201
Rationale1-[(5-fluoropentyl)-1 H -indol-3-yl](4-methyl-1-naphthalenyl) methanone (MAM-2201) is a potent synthetic cannabinoid receptor agonist...
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MicroRNA-451 Regulates Angiogenesis in Intracerebral Hemorrhage by Targeting Macrophage Migration Inhibitory Factor
Intracerebral hemorrhage (ICH) is a subtype of stroke with the highest fatality and disability rate. Up to now, commonly used first-line therapies...
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Coat Color Genetics
The various breeds of cats differ considerably one from the other, not only in terms of their different morphological features but also in terms of...
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Phytochemical Extract from Carica papaya Leaves and Punica granatum Seeds as Therapy Against Cognitive Impairment in a Murine Model
Mild cognitive impairment (MCI) is defined as inter-stage between normal cognitive aging and major neurocognitive disorder (MND). This state of decay...
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Comparative study of the effects of ibuprofen, acetaminophen, and codeine in a model of orofacial postoperative pain in male and female rats
Pain management is a primary goal after oral surgeries, but little is known about sex differences in the sensitivity to analgesics. This study aimed...
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Stellate ganglion block suppresses hippocampal ferroptosis to attenuate cerebral ischemia-reperfusion injury via the Hippo pathway
Ischemic stroke is a disabling and fatal disease caused by the insufficient blood supply to the brain. Stellate ganglion block (SGB) is a type of...
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Rhombomere 2 r2
In this neuromere, the second trigeminal nucleus following the spinal one (see Chap. 3 ) develops, i.e.,...
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Colonization and Persistence Strategies of Staphylococcus aureus
S. aureus is a prime example of a multitalented opportunistic pathogen that possesses a broad array of virulence factors, not infrequently redundant...