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A current perspective on snake venom composition and constituent protein families
Snake venoms are heterogeneous mixtures of proteins and peptides used for prey subjugation. With modern proteomics there has been a rapid expansion...
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Therapeutic Applications of Snake Venom Proteins as Anti-cancer Agents
Cancer is a life debilitating fatal disease that affects millions of lives annually across the world. The current cancer treatments include invasive...
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Naturally occurring and artificially designed antimicrobial peptides: a comparative study of Mastoparan C and BP52
Antimicrobial peptides (AMPs) are naturally occurring molecules that play a vital role in the innate immune responses of various organisms....
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Animal venoms as a source of antiviral peptides active against arboviruses: a systematic review
Arthropod-borne viruses (arboviruses), such as Zika virus (ZIKV), chikungunya virus (CHIKV), dengue virus (DENV), yellow fever virus (YFV), and West...
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Intronic Number Polymorphism in the Genes Encoding Potassium Channel Specific Venom Toxins from Scorpion
AbstractThe dynamic evolution of the scorpion peptide genes in response to selective forces is poorly understood so far. This work aimed to address...
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Identification of purinergic system components in the venom of Bothrops mattogrossensis and the inhibitory effect of specioside extracted from Tabebuia aurea
Snake bites are a severe problem in the countryside of Brazil and are usually attributed to snakes of the genera Bothrops, Crotalus , and Lachesis ....
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Therapeutic potential of antimicrobial peptides against pathogenic protozoa
Protozoal infections cause significant morbidity and mortality in humans and animals. The use of several antiprotozoal drugs is associated with...
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Peptides for microbe-induced cancers: latest therapeutic strategies and their advanced technologies
Cancer is a significant global health concern associated with multiple distinct factors, including microbial and viral infections. Numerous studies...
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In silico prospection of receptors associated with the biological activity of U1-SCTRX-lg1a: an antimicrobial peptide isolated from the venom of Loxosceles gaucho
The emergence of antibiotic-resistant pathogens generates impairment to human health. U1-SCTRX-lg1a is a peptide isolated from a phospholipase D...
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Novel Neurotoxic Activity in Calliophis intestinalis Venom
In this work, we investigated the in vitro neurotoxicity of Calliophis intestinalis venom using chick biventer cervicis neuromuscular preparations...
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Synthetic polypeptide crotamine: characterization as a myotoxin and as a target of combinatorial peptides
AbstractCrotamine is a rattlesnake-derived toxin that causes fast-twitch muscle paralysis. As a cell-penetrating polypeptide, crotamine has been...
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Venom-Derived Peptides Inhibiting Voltage-Gated Sodium and Calcium Channels in Mammalian Sensory Neurons
Pain management is a serious worldwide problem that affects the physical and mental health of all affected humans. As an alternative to opioids,...
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Antimicrobial peptides as potential therapy for gastrointestinal cancers
Since conventional therapy faces limitations in the field of different cancers as well as gastrointestinal cancers, that decrease the survival rate...
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Marine Peptides and Their Bioactive Potentials: New Horizon for Biotherapeutics
Marine ecosystems act as a reservoir of innumerable novel bioactive compounds by instigating stressful environments. Thus, marine bio-resources have...
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Design of Bioengineered Peptides/Proteases as Anti-cancer Reagents with Integrated Omics and Machine Learning Approaches
Cancer is a heterogeneous disorder of uncontrolled growth of cells, which has proven to be a major burden worldwide. Many treatment options are...
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Characterization of novel angiotensin-I converting enzyme inhibitory peptides derived from Taiwan red quinoa (Chenopodium formosanum Koidz.) seed proteins using two sequential bioassay-guided fractionations
Taiwan red quinoa ( Chenopodium formosanum Koidz .) is a pseudo-cereal crop native to Taiwan with a rich protein content that can potentially be a...
