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The Neurohypophysis and Urophysis: Ancient Piscine Neurovascular Interfaces
Vertebrate homoeostasis is regulated by secretion of neurohormones from specialized neuroendocrine neurovascular interfaces such as the...
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Hormonal axes in Drosophila: regulation of hormone release and multiplicity of actions
Hormones regulate development, as well as many vital processes in the daily life of an animal. Many of these hormones are peptides that act at a...
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Circulating Vasoactive Peptide Urotensin II and Relationships with Cardiovascular Disease
The human vasoactive peptide urotensin II (UII) has been described as the most potent vasoconstrictor to date. Despite this, the vasoactive effects...
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Effect of Different Peptides
Eschenhagen et al. (1997) developed a method for culturing embryonic cardiomyocytes in a collagen matrix to produce a coherently contracting...
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Circulating Vasoactive Peptide Urotensin II and Relationships with Cardiovascular Disease
The human vasoactive peptide urotensin II (UII) has been described as the most potent vasoconstrictor to date. Despite this, the vasoactive effects...
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Beginnings at Harpswell, Maine
John Sterling Kingsley, Chair of Biology at Tufts College, started the seasonal Harpswell Laboratory on Casco Bay, ME, in 1898. The organization and...
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Hypothalamic-pituitary-adrenal axis function during perinatal depression
Abnormal function of the hypothalamic-pituitary-adrenal (HPA) axis is an important pathological finding in pregnant women exhibiting major depressive...
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Palosuran Treatment Effective as Bosentan in the Treatment Model of Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a progressive and fatal disorder that any valuable advance in the management of diseases has crucial...
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Effect of Different Peptides
Eschenhagen et al. (1997) developed a method for culturing embryonic cardiomyocytes in a collagen matrix to produce a coherently contracting...
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Contractile responses to rat urotensin II in resting and depolarized basilar arteries
The effects of human urotensin II (hUII) on the vascular tone of different animal species has been studied extensively. However, little has been...
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Neuropeptides and Peptide Hormones
Several types of chemical messengers are employed by the nervous system for local or more diffuse signaling. Among these the peptides are the most...
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Effectiveness of Palosuran in Bleomycin-Induced Experimental Scleroderma
Systemic sclerosis (SSc) is a disease characterized by skin and internal organ involvement. There is progressive accumulation of extracellular matrix...
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The Efficiency of a Urotensin II Antagonist in an Experimental Lung Fibrosis Model
Pulmonary fibrosis is a chronic disease. Urotensin II (U-II) is a new peptide with angiogenic and profibrotic features. Therefore, we aim to evaluate...
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Acanthochondria helicoleni sp. nov. (Copepoda, Chondracanthidae) parasitic on Helicolenus lahillei (Scorpaeniformes, Sebastidae) from Argentinean waters
A new species of a parasitic copepod, Acanthochondria helicoleni sp. nov. (Copepoda, Chondracanthidae), is described and illustrated from specimens...
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Urotensin II acutely increases myocardial length and distensibility: potential implications for diastolic function and ventricular remodeling
Urotensin II (U-II) is a cyclic peptide that may be involved in cardiovascular dysfunction. In the present study, the acute effects of U-II on...
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Caudal neurosecretory system of the zebrafish: ultrastructural organization and immunocytochemical detection of urotensins
The caudal neurosecretory system is described here for the first time in the zebrafish, one of the most important models used to study biological...
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Urotensin II accelerates cardiac fibrosis and hypertrophy of rats induced by isoproterenol
Aim:To study whether urotensin II (UII), a potent vasoconstrictive peptide, is involved in the development of cardiac hypertrophy and fibrogenesis of...
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Behavioral effects of urotensin-II centrally administered in mice
Urotensin-II (U-II) receptors are widely distributed in the central nervous system. Intracerebroventricular (i.c.v.) injection of U-II causes...
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Urotensin II stimulates plasma extravasation in mice via UT receptor activation
The peptide urotensin II (U-II) is the cognate ligand of the G-protein coupled receptor UT (formerly GPR14). A role in the regulation of...
