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  1. Type 1 and Type 2 Diabetes Mellitus

    Diabetes is now a rapidly growing global health problem. The number of people with diabetes has risen from 180 million in 1980 to 422 million in...
    Marco Comoglio, Luca Monge, Elena Vittoria Longhi in Managing Psychosexual Consequences in Chronic Diseases
    Chapter 2023
  2. Technology in the Management of Type 1 and Type 2 Diabetes Mellitus: Recent Status and Future Prospects

    Diabetes mellitus (DM), a metabolic condition with several causes, is characterized by persistent hyperglycemia and improper glucose, lipid, and...
    Titas Biswas, Biplab Kumar Behera, Nithar Ranjan Madhu in Advances in Diabetes Research and Management
    Chapter 2023
  3. Markers of Bacterial Translocation in Type 2 Diabetes Mellitus

    Type 2 Diabetes mellitus is a multifactorial metabolic disorder. The growing body of evidence linking the gut microbiome to host metabolism has been...
    Marwa Ahmed Meheissen in Biomarkers in Diabetes
    Reference work entry 2023
  4. Teplizumab: type 1 diabetes mellitus preventable?

    Type 1 diabetes mellitus (T1DM) is an autoimmune condition driven by T lymphocytes that specifically declines the function of beta cells of pancreas....

    Saurav Misra, Ajay Kumar Shukla in European Journal of Clinical Pharmacology
    Article 01 April 2023
  5. Serum Paraoxonase 1 as a Biomarker: Features and Applications in Type 2 Diabetes Mellitus

    Type 2 diabetes mellitus (T2DM) is a complex metabolic and endocrine disorder. Many factors are responsible for the formation and complications of...
    Berrin Öztaş, Fatma Ceyla Eraldemir, Hale Maral Kır in Biomarkers in Diabetes
    Reference work entry 2023
  6. Biochemical Assay for Measuring Diabetes Mellitus

    Increased blood sugar brought on by inadequate insulin synthesis or activity is known as diabetes mellitus (DM), resulting in disrupted carbohydrate,...
    Taniya Sur, Aishwariya Das, ... Nithar Ranjan Madhu in Advances in Diabetes Research and Management
    Chapter 2023
  7. Diabetes Mellitus and iPSC-Based Therapy

    At present, the number of diabetes mellitus (DM) patients has exceeded 537 million worldwide, and this number continues to increase. Type 1 diabetes...
    Dibyashree Chhetri, Rajesh Nanda Amarnath, ... Dhanavathy Gnanasampanthapandian in Advances in Diabetes Research and Management
    Chapter 2023
  8. Intracellular Lipid Levels and Oxidative Stress in Peripheral Blood Mononuclear Cells in Experimental Type 1 Diabetes Mellitus

    Type 1 diabetes mellitus was modeled in Wistar rats by intraperitoneal injection of streptozotocin (25 mg/kg for 5 days), which led to the appearance...

    V. V. Ivanov, E. E. Buyko, ... V. V. Udut in Bulletin of Experimental Biology and Medicine
    Article 01 April 2023
  9. Diabetes Mellitus: Quantum MicroRNA Language with Artificial Intelligence (MIRAI) as an Early Diagnostic Tool for Type 2 Diabetes Mellitus for Sustainable Healthcare

    Circulating miRNA profiles have long been analyzed as noninvasive biomarkers of metabolic diseases. However, the results of most miRNA biomarker...
    Yoichi Robertus Fujii in The MicroRNA Quantum Code Book
    Chapter 2023
  10. Markers of Bacterial Translocation in Type 2 Diabetes Mellitus

    Type 2 Diabetes mellitus is a multifactorial metabolic disorder. The growing body of evidence linking the gut microbiome to host metabolism has been...
    Marwa Ahmed Meheissen in Biomarkers in Diabetes
    Living reference work entry 2022
  11. LINC-p21 Regulates Pancreatic β-Cell Function in Type 2 Diabetes Mellitus

    This study aimed to investigate the underlying mechanism and assess the biological role of long intergenic non-coding RNA (LINCRNA)-p21 in type 2...

    Zengkun Qian, Fan Cui, ... **aoqin Li in Biochemical Genetics
    Article 12 June 2024
  12. Insulin Resistance in Experimental Type 1 Diabetes Mellitus

    Experimental type 1 diabetes mellitus (T1DM) was induced in rats by daily intraperitoneal injections of alloxan in a dose of 90 mg/kg for 4 days. For...

    V. V. Ivanov, E. E. Buyko, ... E. V. Udut in Bulletin of Experimental Biology and Medicine
    Article 01 April 2022
  13. Serum Paraoxonase 1 as a Biomarker: Features and Applications in Type 2 Diabetes Mellitus

    Type 2 diabetes mellitus (T2DM) is a complex metabolic and endocrine disorder. Many factors are responsible for the formation and complications of...
    Berrin Öztaş, Fatma Ceyla Eraldemir, Hale Maral Kır in Biomarkers in Diabetes
    Living reference work entry 2022
  14. Serum Betatrophin: What It Shows and How It Alters in Gestational Diabetes Mellitus

    Gestational diabetes mellitus is defined as diabetes mellitus diagnosed during the second or third trimester of pregnancy and not clearly associated...
    Rauf Melekoglu, Ebru Celik in Biomarkers in Diabetes
    Reference work entry 2023
  15. Association between Polymorphisms of Heat Shock Protein HSPA5 and Risk of Type 2 Diabetes Mellitus

    We studied the relationship between the HSPA5 gene polymorphisms and the risk of type 2 diabetes mellitus. Genoty** of three SNPs of the HSPA5 gene...

    E. Yu. Klyosova, Yu. E. Azarova, ... A. V. Polonikov in Bulletin of Experimental Biology and Medicine
    Article 01 March 2024
  16. The Search for Immunological Biomarkers in Type 1 Diabetes Mellitus (T1DM) and Multiple Sclerosis (MS): Th40 Cells Provide a Common Autoimmune Link

    Biomarkers to predict autoimmune disease onset or predict progression are sorely lacking. A specific T cell subset present in peripheral blood of...
    David H. Wagner in Biomarkers in Diabetes
    Reference work entry 2023
  17. Distinct and shared genetic architectures of gestational diabetes mellitus and type 2 diabetes

    Gestational diabetes mellitus (GDM) is a common metabolic disorder affecting more than 16 million pregnancies annually worldwide 1 , 2 . GDM is related...

    Amanda Elliott, Raymond K. Walters, ... Elisabeth Widén in Nature Genetics
    Article Open access 05 January 2024
  18. Metabolomic Biomarkers, Metabolite Patterns, and Gestational Diabetes Mellitus

    Gestational diabetes mellitus (GDM) is a common pregnancy complication associated with risk of type 2 diabetes (T2D) for mother and offspring....
    Ellen C. Francis, Wei Perng in Biomarkers in Diabetes
    Reference work entry 2023
  19. Proteomic Biomarkers: What They Are and How Type 2 Diabetes Mellitus Has Similarities with Other Diseases

    Type 2 diabetes mellitus (T2DM) is the most frequent form of diabetes, characterized by insulin resistance and impaired insulin release. Its...
    Karina Braga Gomes in Biomarkers in Diabetes
    Reference work entry 2023
  20. Activation of the osteoblastic HIF-1α pathway partially alleviates the symptoms of STZ-induced type 1 diabetes mellitus via RegIIIγ

    The hypoxia-inducible factor-1α (HIF-1α) pathway coordinates skeletal bone homeostasis and endocrine functions. Activation of the HIF-1α pathway...

    Minglong Qiu, Leilei Chang, ... Changwei Li in Experimental & Molecular Medicine
    Article Open access 01 July 2024
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