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Humoral immunity to SARS-CoV-2 in kidney transplant recipients and dialysis patients: IgA and IgG patterns unraveled after SARS-CoV-2 infection and vaccination
BackgroundInfection with SARS-CoV-2 in high-risk groups such as kidney transplant and dialysis patients is shown to be associated with a more serious...
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Post-transplant Inflammatory Bowel Disease Associated with Donor-Derived TIM-3 Deficiency
Inflammatory bowel disease (IBD) occurring following allogeneic stem cell transplantation (aSCT) is a very rare condition. The underlying...
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Epidemiology of extended-spectrum β-lactamase–producing Enterobacterales infection in kidney transplant recipients
BackgroundExtended-spectrum b-lactamase (ESBL)-producing gram-negative bacilli (ESBL-GNB) are the most important pathogenic bacteria infecting kidney...
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Prediction model for EBV infection following HLA haploidentical matched hematopoietic stem cell transplantation
AimsAllogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective treatment for hematological malignancies. However, viral...
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Proteome Analysis for Inflammation Related to Acute and Convalescent Infection
Infectious diseases are a significant burden in global healthcare. Pathogens engage with different host defense mechanisms. However, it is currently...
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Vaccination with a replication-defective cytomegalovirus vaccine elicits a glycoprotein B-specific monoclonal antibody repertoire distinct from natural infection
Human Cytomegalovirus (HCMV) is the leading infectious congenital infection globally and the most common viral infection in transplant recipients,...
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Laboratory Diagnosis of HEV Infection
Serological and nucleic acid tests for detecting hepatitis E virus (HEV) have been developed for both epidemiologic and diagnostic purposes. The... -
Terminally exhausted CD8+ T cells contribute to age-dependent severity of respiratory virus infection
BackgroundLower respiratory infections are a leading cause of severe morbidity and mortality among older adults. Despite ubiquitous exposure to...
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Clinical characteristics and outcomes of hospitalized kidney transplant recipients with COVID-19 infection in China during the Omicron wave: a single-center cohort study
BackgroundFollowing the short-term outbreak of Coronavirus disease 2019 (COVID-19) in December 2022 in China, clinical data on kidney transplant...
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Risk factors of early bacterial infection and analysis of bacterial composition, distribution and drug susceptibility after cadaveric liver transplantation
BackgroundThis study provided a theoretical basis for the clinical diagnosis and treatment of bacterial infection after liver transplantation through...
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Disease Burden of Primary HHV-6B Infection in Immunocompetent Children
Purpose of ReviewExanthema subitum, which is caused by primary human herpesvirus 6B (HHV-6B) infection, is generally self-limited. However, disease...
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Comparable anti-CMV responses of transplant donor and third-party CMV-specific T cells for treatment of CMV infection after allogeneic stem cell transplantation
Adoptive transfer of cytomegalovirus (CMV)-specific cytotoxic T lymphocytes (CMV-CTLs) from original transplant donors or third-party donors was...
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One-year breakthrough SARS-CoV-2 infection and correlates of protection in fully vaccinated hematological patients
The long-term clinical efficacy of SARS-CoV-2 vaccines according to antibody response in immunosuppressed patients such as hematological patients has...
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Sapovirus infection as another cause of persistent viral diarrhea: case series and review of the literature
Human sapovirus (HuSaV) is a common cause of gastroenteritis worldwide and is responsible for approximately 4% of acute gastroenteritis episodes in...
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Decreased frequency of Th22 cells and IL-22 cytokine in kidney transplant patients with active cytomegalovirus infection
BackgroundThe immunity of CD4 + T cell subsets against human cytomegalovirus (HCMV) is considerable due to their essential role in controlling the...
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Chronic COVID-19 infection in an immunosuppressed patient shows changes in lineage over time: a case report
BackgroundThe COVID-19 pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 virus, emerged in late 2019 and spready globally. Many...
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The impact of HLA polymorphism on herpesvirus infection and disease
Human Leukocyte Antigens (HLA) are cell surface molecules, central in coordinating innate and adaptive immune responses, that are targets of strong...
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X-Linked Agammaglobulinemia: Infection Frequency and Infection-Related Mortality in the USIDNET Registry
X-linked agammaglobulinemia (XLA) is a primary immunodeficiency disorder caused by mutations in the Bruton tyrosine kinase ( BTK ) gene leading to B...
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Prevalence and Characteristics of Non-tuberculous Mycobacteria (NTM) Infection in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation: a Systematic Review and Meta-analysis
PurposeNon-tuberculous mycobacteria (NTM) infections in hematopoietic stem cell transplantation (HSCT) recipients represent a diagnostic and...