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Grave-to-cradle: human embryonic lineage tracing from the postmortem body
Curiosity concerning the process of human creation has been around for a long time. Relevant questions seemed to be resolved with the knowledge of...
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Analyzing Thalamocortical Tract-Tracing Experiments in a Common Reference Space
Current mesoscale connectivity atlases provide limited information about the organization of thalamocortical projections in the mouse brain. Labeling...
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Return of the Tbx5; lineage-tracing reveals ventricular cardiomyocyte-like precursors in the injured adult mammalian heart
The single curative measure for heart failure patients is a heart transplantation, which is limited due to a shortage of donors, the need for...
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Contact tracing for vancomycin-resistant Enterococcus faecium (VRE): evaluation of the Dutch policy of quintuple screening cultures
Detection of vancomycin-resistant Enterococcus faecium (VRE) is hampered by low sensitivity of rectal swab cultures. This study aimed to define the...
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Investigations of brain-wide functional and structural networks of dopaminergic and CamKIIα-positive neurons in VTA with DREADD-fMRI and neurotropic virus tracing technologies
BackgroundThe ventral tegmental area (VTA) contains heterogeneous cell populations. The dopaminergic neurons in VTA play a central role in reward and...
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Tracing the journey of poxviruses: insights from history
The historical significance of the poxviruses is profound, largely due to the enduring impact left by smallpox virus across many centuries. The...
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Tracing vitamins on the long non-coding lane of the transcriptome: vitamin regulation of LncRNAs
A major revelation of genome-scale biological studies in the post-genomic era has been that two-thirds of human genes do not encode proteins. The...
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Development of a web-based contact tracing and point-of-care-testing workflow for SARS-CoV-2 at a German University Hospital
IntroductionIn late 2019, a novel coronavirus was detected in China. Supported by its respiratory transmissibility, even by people infected without...
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Preferential subcortical collateral projections of pedunculopontine nucleus-targeting cortical pyramidal neurons revealed by brain-wide single fiber tracing
The pedunculopontine nucleus (PPN) is a heterogeneous midbrain structure involved in various brain functions, such as motor control, learning,...
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Tracing the lactate shuttle to the mitochondrial reticulum
Isotope tracer infusion studies employing lactate, glucose, glycerol, and fatty acid isotope tracers were central to the deduction and demonstration...
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Delineating the organization of projection neuron subsets in primary visual cortex with multiple fluorescent rabies virus tracing
The impressive functions of the brain rely on an extensive connectivity matrix between specific neurons, the architecture of which is frequently...
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Actual status of patient information sharing among healthcare delivery facilities: a survey by the third subcommittee, committee on academic research, the Japanese society of hospital pharmacists
BackgroundInformation sharing among medical professionals is important for providing quality medical care. The purpose of the present study was to...
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Neuroanatomical tract-tracing techniques that did go viral
Neuroanatomical tracing methods remain fundamental for elucidating the complexity of brain circuits. During the past decades, the technical arsenal...
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Metabolic pathway analysis using stable isotopes in patients with cancer
Metabolic reprogramming is central to malignant transformation and cancer cell growth. How tumours use nutrients and the relative rates of...
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Tracing TET1 expression in prostate cancer: discovery of malignant cells with a distinct oncogenic signature
BackgroundTen–eleven translocation methylcytosine dioxygenase 1 (TET1) is involved in DNA demethylation and transcriptional regulation, plays a key...
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A Practical Computer Aided Diagnosis System for Breast Ultrasound Classifying Lesions into the ACR BI-RADS Assessment
PurposeIn this paper, we propose an open-source deep learning-based computer-aided diagnosis system for breast ultrasound images based on the Breast...
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In situ reprogramming of cardiac fibroblasts into cardiomyocytes in mouse heart with chemicals
Cardiomyocytes are terminal differentiated cells and have limited ability to proliferate or regenerate. Condition like myocardial infarction causes...
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Tracing in vivo the dorsal loop of the optic radiation: convergent perspectives from tractography and electrophysiology compared to a neuroanatomical ground truth
The temporo-parietal junction (TPJ) is a cortical area contributing to a multiplicity of visual, language-related, and cognitive functions. In line...
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Globus pallidus is not independent from striatal direct pathway neurons: an up-to-date review
Striatal projection neurons, which are classified into two groups—direct and indirect pathway neurons, play a pivotal role in our understanding of...
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Robust estimation of cortical similarity networks from brain MRI
Structural similarity is a growing focus for magnetic resonance imaging (MRI) of connectomes. Here we propose Morphometric INverse Divergence (MIND),...
