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Role and Pathophysiology of Protozoan Parasites Causing Liver Diseases
Protozoans are responsible for numerous chronic and severe human diseases worldwide. These are transmitted through food and water along with blood...
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A fluorescence-based assay for Trichomonas vaginalis drug screening
BackgroundThe emergence and spread of drug resistance in Trichomonas vaginalis parasites has become an important concern in trichomoniasis...
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In vitro activity of amixicile against T. vaginalis from clinical isolates
Trichomoniasis is a sexually transmitted infection in humans caused by the protozoan Trichomonas vaginalis, the leading causative agent of vaginitis...
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Metronidazole and Clindamycin
Metronidazole compound (1-[2-hydroxyethyl]-2-hydroxymethyl-5-nitroimidazole) is commonly used to treat anaerobic infections. It is the only one of...
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The antimicrobial peptides LL-37, KR-20, FK-13 and KR-12 inhibit the growth of a sensitive and a metronidazole-resistant strain of Trichomonas vaginalis
The parasite Trichomonas vaginalis is the aetiologic agent of trichomoniasis, the most common non-viral sexually transmitted disease worldwide. This...
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Pharmacokinetic Interaction Between Imatinib and Metformin in Rats
Background and ObjectiveImatinib is primarily transported into the liver by organic cation transporter 1 (OCT1), organic anion transporting...
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Chemotherapy of Parasitic Infections
Effective control of parasitic diseases requires a multidimensional approach, including chemotherapy by drugs. Drug therapy needs to be supplemented...
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Is hybrid therapy more efficient in the eradication of Helicobacter pylori infection? A systematic review and meta-analysis
IntroductionHybrid therapy (HT) is a non-bismuth quadruple therapy created to surpass Helicobacter pylori ’s ( H. pylori ) resistance rates to...
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Trichomoniasis
Trichomonas vaginalis is an extracellular parasite that primarily infects the squamous epithelium of the genital tract and is sexually acquired. It...
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Detection of Trichomonas vaginalis by Allplex™ STI Essential Assay (Seegene) in clinical samples from the Brazilian public health system users
The failures in Trichomonas vaginalis (TV) infection diagnosis leave more than half of cases unidentified. In this report, urine and vaginal...
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New Aspects in the Study of Lactobacillus iners
A cultural microbiological study of the vaginal microbiota of patients of reproductive age was carried out to isolate the species Lactobacillus iners ...
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Applying pharmacokinetic/pharmacodynamic measurements for linezolid in critically ill patients: optimizing efficacy and reducing resistance occurrence
PurposeLinezolid (LZD) levels are frequently insufficient in intensive care unit (ICU) patients receiving standard dose, which is predictive of a...
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Pharmacotherapy of Microbial Diseases
Microbial diseases comprise a significant portion of the global disease burden. Starting from moderate flulike condition to serious life-threatening...
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Understanding the Pharmacology and Pharmacotherapeutics for Infectious Diseases
Infectious diseases are caused by living microorganisms such as bacteria, virus, parasite, and fungi that infect millions of people around the globe....
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Introduction of protein vaccine candidate based on AP65, AP33, and α-actinin proteins against Trichomonas vaginalis parasite: an immunoinformatics design
BackgroundTrichomonas vaginalis is the most common nonviral sexually transmitted disease (STI) worldwide. Vaccination is generally considered to be...
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Giardiasis from a One Health Perspective
The flagellated protozoan Giardia duodenalis is the etiologic agent of giardiasis, a very common gastrointestinal infection of mammals, including...
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Anti-Trichomonas vaginalis activity and chemical analysis of metabolites produced by marine-associated fungi
Trichomoniasis is the most common non-viral sexually transmitted infection worldwide and it may have serious consequences, especially for women....
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The Challenges with Canine Giardia
This chapter reviews the prevalence of Giardia and Giardia Assemblages in people and dogs and the risks that dogs may present as sources of human...