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Showing 1-20 of 480 results

  1. CHI3L1 promotes myocardial fibrosis via regulating lncRNA TUG1/miR-495-3p/ETS1 axis

    Abnormal levels of CHI3L1 and lnc TUG1 are often associated with myocardial fibrosis, and their specific expressions may be closely related to the...

    Yunpeng Sun, Xue Shan, ... Dashi Ma in Apoptosis
    Article 07 June 2023

  2. LncRNA TUG1 Promoted Stabilization of BAG5 by Binding DDX3X to Exacerbate Ketamine-Induced Neurotoxicity

    As a clinically widely used anesthetic, ketamine (KET) has been reported to cause neurotoxicity in patients. Our work aimed to probe the function of...

    Xue Lei, **angFei Fang, ... Huan Liu in Neurotoxicity Research
    Article 24 September 2022

  3. Diagnostic and Prognostic Value of Deregulated Circulating Long Non-coding RNA TUG1 in Elderly Patients with Severe Pneumonia

    To investigate the expression pattern of long non-coding RNA TUG1 in elderly patients with severe community-acquired pneumonia (sCAP) and evaluate...

    Kai Gong, Jiao Xu, Jianlei Tang in Inflammation
    Article 15 September 2022

  4. The pathogenic roles of lncRNA-Taurine upregulated 1 (TUG1) in colorectal cancer

    Colorectal cancer (CRC) is a gastrointestinal tumor that develops from the colon, rectum, or appendix. The prognosis of CRC patients especially those...

    Shirin Azizidoost, Ava Nasrolahi, ... Maryam Farzaneh in Cancer Cell International
    Article Open access 04 November 2022

  5. Interfering TUG1 Attenuates Cerebrovascular Endothelial Apoptosis and Inflammatory injury After Cerebral Ischemia/Reperfusion via TUG1/miR-410/FOXO3 ceRNA Axis

    Background Emerging studies illustrate that long non-coding RNA TUG1 (TUG1) participates in neuron death after ischemia. However, the role of TUG1...

    Zhirong He, Yanyan Zhao, ... Fen Lu in Neurotoxicity Research
    Article 01 December 2021

  6. LncRNA Tug1 Contributes Post-stroke NLRP3 Inflammasome-Dependent Pyroptosis via miR-145a-5p/Tlr4 Axis

    Pyroptosis, a type of programmed cell death illuminated by inflammasomes and active caspases, is implicated in post-stroke inflammation. Our previous...

    Meiling Yao, Ying Luo, ... Jian Yu in Molecular Neurobiology
    Article 22 August 2022

  7. Hypermethylation in Ovarian Cancer of Long Noncoding RNA Genes: HOTAIR, GAS5, LINC00472, LINC00886, TUG1

    Abstract

    Recently, more and more data have been accumulating indicating the role of long noncoding RNAs (lncRNAs) in the regulation of biological...

    A. M. Burdennyy, S. S. Lukina, ... E. A. Braga in Russian Journal of Genetics
    Article 21 May 2024

  8. Ginsenoside Rg3 alleviates septic liver injury by regulating the lncRNA TUG1/miR-200c-3p/SIRT1 axis

    Background

    Studies have shown that ginsenoside R3 (Rg3) plays a protective role in sepsis-induced organ injuries and mitochondrial dysfunction. Long...

    Pan Wu, **ao Yu, ... Wei **ng in Journal of Inflammation
    Article Open access 20 December 2021

  9. Bupivacaine Induces ROS-Dependent Autophagic Damage in DRG Neurons via TUG1/mTOR in a High-Glucose Environment

    Bupivacaine (BP) is a commonly clinically used local anesthetic (LA). Current studies suggest that neurological complications are increased in...

    Luying Lai, Yongwei Wang, ... Shiyuan Xu in Neurotoxicity Research
    Article 18 January 2022

  10. LncRNA-TUG1 promotes the progression of infantile hemangioma by regulating miR-137/IGFBP5 axis

    Background

    Previous studies indicated that lncRNA taurine upregulated gene 1 (TUG1) played essential roles in human cancers. This study aimed to...

    Lili Zhou, **ao Jia, **angzheng Yang in Human Genomics
    Article Open access 06 August 2021

  11. The renoprotective effects of gallic acid on cisplatin-induced nephrotoxicity through anti-apoptosis, anti-inflammatory effects, and downregulation of lncRNA TUG1

    Cisplatin, an antineoplastic drug used in cancer therapy, -induced nephrotoxicity mediated by the production of reactive oxygen species (ROS). Gallic...

    Negin Amini, Mohammad Badavi, ... Mahin Taheri Moghadam in Naunyn-Schmiedeberg's Archives of Pharmacology
    Article 18 March 2022

  12. Dexmedetomidine hydrochloride inhibits hepatocyte apoptosis and inflammation by activating the lncRNA TUG1/miR-194/SIRT1 signaling pathway

    Background

    Liver injury seriously threatens the health of people. Meanwhile, dexmedetomidine hydrochloride (DEX) can protect against liver injury....

    **ao-**a Gu, **ao-**a Xu, ... Jian Mo in Journal of Inflammation
    Article Open access 26 May 2021

  14. LncRNA TUG1 regulates the development of ischemia-reperfusion mediated acute kidney injury through miR-494-3p/E-cadherin axis

    Background

    Acute kidney injury (AKI) results from renal dysfunction caused by various causes, resulting in high mortality. The underlying mechanisms...

    Li Chen, Jun-Ying Xu, Hong-Bao Tan in Journal of Inflammation
    Article Open access 04 March 2021

  15. The Role of lncRNA TUG1 in the Parkinson Disease and Its Effect on Microglial Inflammatory Response

    Parkinson’s disease (PD) is a common neurodegenerative disease in the middle-aged and elderly populations. The purpose of this study was to...

    Jiang Cheng, Yangyang Duan, ... Haining Li in NeuroMolecular Medicine
    Article 21 October 2020

  18. TUG1/miR-133b/CXCR4 axis regulates cisplatin resistance in human tongue squamous cell carcinoma

    Background

    Long noncoding RNA taurine upregulated 1 (TUG1) has been reported to play an important role in human cancers. However, little is known...

    Ke Zhang, Hong Zhou, ... Xuan** Cao in Cancer Cell International
    Article Open access 06 May 2020

  19. RETRACTED ARTICLE: Knockdown of long non-coding RNA TUG1 depresses apoptosis of hippocampal neurons in Alzheimer’s disease by elevating microRNA-15a and repressing ROCK1 expression

    Objective

    Many studies have already suggested the role of long non-coding RNAs (lncRNAs) in Alzheimer’s disease (AD), but the functions of lncRNA...

    **a Li, Sheng-Wu Wang, ... Hai-Ming Cong in Inflammation Research
    Article 23 June 2020

  20. Downregulation of lncRNA TUG1 attenuates inflammation and apoptosis of renal tubular epithelial cell induced by ischemia-reperfusion by sponging miR-449b-5p via targeting HMGB1 and MMP2

    We aimed to evaluate the functions of long non-coding RNA taurine upregulated gene 1 (lncRNA TUG1) in renal ischemia-reperfusion (I/R) injury and...

    Yuan Xu, Yulin Niu, ... Guanghui Pan in Inflammation
    Article 23 March 2020
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