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Folic Acid as a Bimodal Optical Probe for the Detection of TNT
Rapid and onsite detection of nitroaromatic explosive 2,4,6-trinitrotoluene (TNT) is very crucial for the safety and security of human life as well...
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A Simple Determination of Trinitrotoluene (TNT) Based on Fluorescence Quenching of Rhodamine 110 with FRET Mechanism
Sensitive and selective detection of nitroaromatic explosives is an important issue in regard to human health, environment, public security and...
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The explosive trinitrotoluene (TNT) induces gene expression of carbonyl reductase in the blue mussel (Mytilus spp.): a new promising biomarker for sea dumped war relicts?
Millions of tons of all kind of munitions, including mines, bombs and torpedoes have been dumped after World War II in the marine environment and do...
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Exploring treatment outcomes in Stage II-III rectal cancer patients undergoing neoadjuvant therapy at a tertiary care center in Pakistan: a comprehensive analysis of pathological outcomes
BackgroundRectal cancer treatment has transformed in recent years, with neoadjuvant treatment (NT) and total neoadjuvant treatment (TNT) aiming to...
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Total neoadjuvant therapy with short-course radiotherapy Versus long-course neoadjuvant chemoradiotherapy in Locally Advanced Rectal cancer, Korean trial (TV-LARK trial): study protocol of a multicentre randomized controlled trial
BackgroundFor locally advanced rectal cancer (LARC), total neoadjuvant therapy (TNT) may enhance tumour response, reduce recurrence, and improve...
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Myogenic tissue nanotransfection improves muscle torque recovery following volumetric muscle loss
This work rests on our non-viral tissue nanotransfection (TNT) platform to deliver MyoD (TNT MyoD ) to injured tissue in vivo. TNT MyoD was performed on...
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Preoperative chemoradiotherapy using tegafur/uracil, oral leucovorin, and irinotecan (TEGAFIRI) followed by oxaliplatin-based chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: the study protocol for a phase II trial
BackgroundTotal neoadjuvant therapy (TNT) is a novel treatment strategy that is an alternative to preoperative chemoradiotherapy (CRT) for locally...
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Preoperative sequential short-course radiation therapy and FOLFOX chemotherapy versus long-course chemoradiotherapy for locally advanced rectal cancer: a multicenter, randomized controlled trial (SOLAR trial)
BackgroundPreoperative (chemo)radiotherapy has been widely used as an effective treatment for locally advanced rectal cancer (LARC), leading to a...
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Comparison of ticagrelor and clopidogrel on platelet function and prognosis in unstable angina
PurposeThis study aims to compare the effects of ticagrelor and clopidogrel on platelet function, cardiovascular prognosis, and bleeding in patients...
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Correction to: The explosive trinitrotoluene (TNT) induces gene expression of carbonyl reductase in the blue mussel (Mytilus spp.): a new promising biomarker for sea dumped war relicts?
A correction to this paper has been published: https://doi.org/10.1007/s00204-021-03088-y
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The efficacy and safety of short-course radiotherapy followed by sequential chemotherapy and Cadonilimab for locally advanced rectal cancer: a protocol of a phase II study
BackgroundFor patients with locally advanced rectal cancer (LARC), total neoadjuvant therapy (TNT), namely, intensifying preoperative treatment...
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Mechanosensitive Ion Channel TMEM63A Gangs Up with Local Macrophages to Modulate Chronic Post-amputation Pain
Post-amputation pain causes great suffering to amputees, but still no effective drugs are available due to its elusive mechanisms. Our previous...
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The prognostic value of cardiac troponin T in different age groups of traumatic brain injury patients
BackgroundThe cardiac dysfunction has been confirmed as a common non-neurological complication and associated with increased mortality in traumatic...
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Short-course radiotherapy combined with CAPOX and Toripalimab for the total neoadjuvant therapy of locally advanced rectal cancer: a randomized, prospective, multicentre, double-arm, phase II trial (TORCH)
BackgroundFor patients with locally advanced (T3-4/N +) rectal cancer (LARC), the standard treatment is neoadjuvant chemoradiotherapy combined with...
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Related neural networks underlie suppression of emotion, memory, motor processes as identified by data-driven analysis
BackgroundGoal-directed behavior benefits from self-regulation of cognitive and affective processes, such as emotional reactivity, memory retrieval,...
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Ultrastructural analysis and three-dimensional reconstruction of cellular structures involved in SARS-CoV-2 spread
The cytoskeleton not only deals with numerous interaction and communication mechanisms at the cellular level but also has a crucial role in the viral...
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Exon skip** caused by splicing mutation in TNNT1 nemaline myopathy
The TNNT1 gene encoding the slow skeletal muscle TnT has been identified as a causative gene for nemaline myopathy. TNNT1 nemaline myopathy is mainly...
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Global longitudinal strain assessment of cardiac function and extravascular lung water formation after diving using semi-closed circuit rebreather
PurposeThe aim of the present investigation is to study the relationship of ventricular global longitudinal strain (GLS) and ultrasound lung comets...
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Recursive Genome Function of the Cerebellum: Geometric Unification of Neuroscience and Genomics
Recursive Fractal Genome Function in the geometric mind frame of Tensor Network Theory (TNT) leads through FractoGene to a mathematical unification... -
Immediate and 24-h post-marathon cardiac troponin T is associated with relative exercise intensity
PurposeWe aimed at exploring whether cardiopulmonary fitness, echocardiographic measures and relative exercise intensity were associated with...