Search
Search Results
-
Rise of the natural red pigment ‘prodigiosin’ as an immunomodulator in cancer
Cancer is a heterogeneous disease with multifaceted drug resistance mechanisms (e.g., tumour microenvironment [TME], tumour heterogeneity, and immune...
-
CXCL9 secreted by tumor-associated dendritic cells up-regulates PD-L1 expression in bladder cancer cells by activating the CXCR3 signaling
BackgroundTumor-associated dendritic cells (TADCs) can interact with tumor cells to suppress anti-tumor T cell immunity. However, there is no...
-
Tumor-promoting myeloid cells in the pathogenesis of human oncoviruses: potential targets for immunotherapy
Oncoviruses, known as cancer-causing viruses, are typically involved in cancer progression by inhibiting tumor suppressor pathways and uncontrolled...
-
Perspective view of allogeneic IgG tumor immunotherapy
Allogeneic tumors are eradicated by host immunity; however, it is unknown how it is initiated until the report in Nature by Yaron Carmi et al. in...
-
Tumor Promoting Inflammation
Purpose of the ReviewIn this review, the role of inflammation on tumorigenesis with the scope of its tumor-promoting role as an enabling...
-
Modulating ferroptosis sensitivity: environmental and cellular targets within the tumor microenvironment
Ferroptosis, a novel form of cell death triggered by iron-dependent phospholipid peroxidation, presents significant therapeutic potential across...
-
Timing of the Major Metabolic Switches in Immune Cell Activation and Differentiation During Cancer Development
The immune system is divided into two parts: innate and adaptive. Immune cells derived from myeloid and lymphoid progenitor cells play a critical...
-
Impact of NSCLC metabolic remodeling on immunotherapy effectiveness
It is known that metabolic reprogramming (MR) contributes to tumorigenesis through the activation of processes that support survival of cells,...
-
MALAT1-related signaling pathways in colorectal cancer
Colorectal cancer (CRC) is one of the most lethal and prevalent solid malignancies worldwide. There is a great need of accelerating the development...
-
Targeting cGAS/STING signaling-mediated myeloid immune cell dysfunction in TIME
Myeloid immune cells (MICs) are potent innate immune cells serving as first responders to invading pathogens and internal changes to cellular...
-
mRNA in cancer immunotherapy: beyond a source of antigen
mRNA therapeutics have become the focus of molecular medicine research. Various mRNA applications have reached major milestones at high speed in the...
-
Inflammation and Cancer
Virchow (1864) observed that tumor stroma is frequently invaded by inflammatory cells and proposed a relationship between inflammation and cancer for...
-
Immunometabolism in biofilm infection: lessons from cancer
BackgroundBiofilm is a community of bacteria embedded in an extracellular matrix, which can colonize different human cells and tissues and subvert...
-
Lipid Metabolism and Tumor Antigen Presentation
Tumors always evade immune surveillance and block T cell activation in a poorly immunogenic and immunosuppressive environment. Cancer cells and...
-
Inflammatory Components of the Thyroid Cancer Microenvironment: An Avenue for Identification of Novel Biomarkers
The incidence of thyroid cancer in the United States is on the rise with an appreciably high disease recurrence rate of 20–30%. Anaplastic thyroid...
-
The co-delivery of adenovirus-based immune checkpoint vaccine elicits a potent anti-tumor effect in renal carcinoma
Immune-based checkpoint therapy has made significant progress in cancer treatment, but its therapeutic effect is limited. A replication-defective...
-
Rediscovering Medicinal Activity and Food Significance of Shogaol (4, 6, 8, 10, and 12): Comprehensive Review
Ginger Zingiber officinale Roscoe is a natural dietary rhizome. The plant is a herbaceous tropical monocotyledon perennial plant which belongs to the...
-
Interleukin (IL)-7 Signaling in the Tumor Microenvironment
Interleukin (IL)-7 plays an important immunoregulatory role in different types of cells. Therefore, it attracts researcher’s attention, but despite...
-
Next Generation of Cancer Immunotherapy: Targeting the Cancer-Immunity Cycle with Nanotechnology
Although cancer immunotherapy has made great progress in treating a variety of malignances, its clinical efficacy is often dampened by tumor...
-
Non-invasive brain stimulation for improving gait, balance, and lower limbs motor function in stroke
ObjectivesThis systematic review and meta-analysis aim to summarize and analyze the available evidence of non-invasive brain stimulation/spinal cord...
