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  1. Association of systemic immune-inflammation index and systemic inflammation response index with chronic kidney disease: observational study of 40,937 adults

    Background

    Chronic kidney disease (CKD) is linked to immunity and inflammation. Systemic immune-inflammation index (SII) and systemic inflammation...

    Peixian Huang, Yanpei Mai, ... Yaqing Wen in Inflammation Research
    Article 15 March 2024
  2. Association between the systemic immune inflammation index and periodontitis: a cross-sectional study

    Background

    Periodontitis is a chronic oral inflammatory disease that seriously affects people's quality of life. The purpose of our study was to...

    Junfeng Guo, Rufu Xu, ... Rong Zhang in Journal of Translational Medicine
    Article Open access 23 January 2024
  3. The relationship between systemic inflammation index, systemic immune-inflammatory index, and inflammatory prognostic index and 90-day outcomes in acute ischemic stroke patients treated with intravenous thrombolysis

    Background and purpose

    To explore the association of systemic inflammatory index (SIRI), systemic immune-inflammatory index (SII) and inflammatory...

    Fei Ma, Lulu Li, ... Minghua Wu in Journal of Neuroinflammation
    Article Open access 30 September 2023
  4. Effects of Current Psychotropic Drugs on Inflammation and Immune System

    The immune system and inflammation are involved in the pathological progression of various psychiatric disorders such as depression or major...
    Shvetank Bhatt, Arghya Kusum Dhar, ... Ashish Suttee in Neuroinflammation, Gut-Brain Axis and Immunity in Neuropsychiatric Disorders
    Chapter 2023
  5. Prognostic significance of prognostic nutritional index and systemic immune‐inflammation index in patients after curative breast cancer resection: a retrospective cohort study

    Background

    Nutritional status and inflammation are closely associated with poor outcome in malignant tumors. However, the prognostic impact of...

    Tai Xu, Si-Ming Zhang, ... Jian-Juan Li in BMC Cancer
    Article Open access 03 November 2022
  6. Predicting response to immunotherapy in gastric cancer via assessing perineural invasion-mediated inflammation in tumor microenvironment

    Background

    The perineural invasion (PNI)-mediated inflammation of the tumor microenvironment (TME) varies among gastric cancer (GC) patients and...

    Xunjun Li, Yiyun Wang, ... Tao Chen in Journal of Experimental & Clinical Cancer Research
    Article Open access 11 August 2023
  7. The association between systemic immune-inflammation index and cardiotoxicity related to 5-Fluorouracil in colorectal cancer

    Background and aims

    The cardiotoxicity related to 5-Fluorouracil (5-FU) in cancer patients has garnered widespread attention. The systemic...

    **aoqin Liu, Yan Wang, ... Weiwei Chen in BMC Cancer
    Article Open access 29 June 2024
  8. Risk Factors Associated with Chronic Inflammation and Management Strategies

    Inflammation serves as the body’s defensive mechanism against both external and internal entities that pose a threat to homeostasis. However, an...
    Virendra Kumar Singh, Anurag Tripathi, Deepti Nagesh Nayak in Inflammation Resolution and Chronic Diseases
    Chapter 2024
  9. Innate Immunity and Inflammation

    In this chapter, we will explain that the innate immune system has effector functions that allow a very early response to invading pathogens as well...
    Carsten Carlberg, Eunike Velleuer, Ferdinand Molnár in Molecular Medicine
    Chapter 2023
  10. Utility of prognostic nutritional index and systemic immune-inflammation index in oral cancer treatment

    Purpose

    This study aimed to evaluate the utility of inflammation-based prognostic scores (IBPS) and systemic immune-inflammation index (SII) in the...

    Kosei Kubota, Ryohei Ito, ... Wataru Kobayashi in BMC Cancer
    Article Open access 07 April 2022
  11. Prognostic value of systemic inflammation response index in nasopharyngeal carcinoma with negative Epstein-Barr virus DNA

    Background

    Inflammatory parameters and Epstein–Barr virus (EBV) DNA status have been confirmed to be associated with prognosis in nasopharyngeal...

    **aofei Yuan, Hua Yang, ... Fan Wang in BMC Cancer
    Article Open access 05 August 2022
  12. Inflammation Biomarkers in Huntington’s Disease

    Neurodegenerative diseases share many features, such as inflammation. Accumulating evidence support the role of neuroinflammation in the pathogenesis...
    Chapter 2023
  13. Association between systemic immune-inflammation index and metabolic syndrome and its components: results from the National Health and Nutrition Examination Survey 2011–2016

    Background

    Metabolic syndrome (MetS), a worldwide public health problem, affects human health and quality of life in a dramatic manner. A growing...

    Yang Zhao, Wenyu Shao, ... **aofei Hu in Journal of Translational Medicine
    Article Open access 04 October 2023
  14. Clinical usefulness of the lymphocyte-to-monocyte ratio and aggregate index of systemic inflammation in patients with esophageal cancer: a retrospective cohort study

    Background

    Multiple perioperative inflammatory markers are considered important factors affecting the long-term survival of esophageal cancer (EC)...

    Hui-Ke Wang, Qian Wei, ... Feng Wang in Cancer Cell International
    Article Open access 27 January 2023
  15. Effects of resistance training on heat shock response (HSR), HSP70 expression, oxidative stress, inflammation, and metabolism in middle-aged people

    Resistance training (RT) can increase the heat shock response (HSR) in the elderly. As middle-aged subjects already suffer physiological declines...

    Carlos Henrique de Lemos Muller, Helena Trevisan Schroeder, ... Mauricio Krause in Journal of Physiology and Biochemistry
    Article 06 November 2023
  16. Intravenous injection of cyclosporin A loaded lipid nanocapsules fights inflammation and immune system activation in a mouse model of diabetic retinopathy

    Inflammation and immune system activation are key pathologic events in the onset and escalation of diabetic retinopathy (DR). Both are driven by...

    Marilena Bohley, Andrea E. Dillinger, ... Achim Goepferich in Drug Delivery and Translational Research
    Article Open access 19 May 2023
  17. Prognostic value of the advanced lung cancer inflammation index in patients with gastric cancer after radical gastrectomy: a propensity-score matching cohort study and meta-analysis

    Background

    Insufficient evidence existed about the prognostic role of the advanced lung cancer inflammation index (ALI) for gastric cancer patients...

    Huayang Pang, Lingyan Dai, ... Hao Sun in BMC Cancer
    Article Open access 13 May 2024
  18. Associations between sex, body mass index and the individual microglial response in Alzheimer’s disease

    Background and objectives

    18-kDa translocator protein position-emission-tomography (TSPO-PET) imaging emerged for in vivo assessment of...

    Gloria Biechele, Boris-Stephan Rauchmann, ... Matthias Brendel in Journal of Neuroinflammation
    Article Open access 23 January 2024
  19. A novel preoperative inflammation score system established for postoperative prognosis predicting of intrahepatic cholangiocarcinoma

    Background

    Inflammation is implicated in tumorigenesis and has been reported as an important prognostic factor in cancers. In this study, we aimed to...

    Jun Fu, Qinjunjie Chen, ... Yongyi Zeng in BMC Cancer
    Article Open access 24 February 2023
  20. Prognostic value of the pretreatment systemic immune-inflammation index in patients with prostate cancer: a systematic review and meta-analysis

    Background

    The systemic immune-inflammation index (SII) is a novel biomarker to predict the prognosis of some malignant tumors based on neutrophil,...

    Linghao Meng, Yujia Yang, ... **ang Li in Journal of Translational Medicine
    Article Open access 04 February 2023
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