Search
Search Results
-
Synaptic Tagging and Capture From Synapses to Behavior
This reference presents a detailed exploration of the synaptic tagging and capture model, which has been proposed to provide a conceptual basis for...
-
Synaptic Integration at Neuron-OPC Synapses
The synapses between neurons and oligodendrocyte precursor cells (OPCs) in the central nervous system (CNS) have similar ultrastructures as...
-
Synaptic Vesicles Methods and Protocols
This book provides protocols on the preparation of synaptic vesicles from different model systems and provides instructions for functional...
-
Compartmentalization of Synaptic Tagging and Capture
Testing of the synaptic tagging and capture (STC) hypothesis has produced remarkable work on the understanding of how a single neuron undergoes...
-
Molecular Mechanisms Underlying Synaptic Tagging and Consolidation
After a synapse undergoes long-term potentiation (LTP), it acquires a newly remodeled molecular and structural organization. This reorganization over...
-
Activity-Dependent Protein Transport as a Synaptic Tag
The “synaptic tagging and capture” hypothesis proposes that a hypothetical, cell biological mark is activated in the synapses undergoing early-phase...
-
Decreased Synaptic Vesicle Glycoprotein 2A Binding in the Human Postmortem Essential Tremor Cerebellum: Evidence of Reduction in Synaptic Density
ObjectiveDespite being one of the most prevalent neurological diseases, the pathophysiology of essential tremor (ET) is not fully understood....
-
Understanding neural circuit function through synaptic engineering
Synapses are a key component of neural circuits, facilitating rapid and specific signalling between neurons. Synaptic engineering — the synthetic...
-
Modulation of synaptic transmission through O-GlcNAcylation
O-GlcNAcylation is a posttranslational modification where N-acetylglucosamine (O-GlcNAc) is attached and detached from a serine/threonine position by...
-
Synaptic Tagging and Metaplasticity as Mediators of Neuronal Consciousness
Forming memories for highly arousing, novel, or salient events engages synaptic mechanisms that allow the association of temporally remote events and...
-
Synaptic loss and its association with symptom severity in Parkinson’s disease
Parkinson’s disease (PD) is the fastest growing neurodegenerative disease, but at present there is no cure, nor any disease-modifying treatments....
-
Electrophysiological Analysis of Synaptic Transmission
This second edition volume expands on the previous edition with discussions on the latest techniques used to study synaptic transmissions. The...
-
Synaptic Cooperation and Competition: Two Sides of the Same Coin?
Memories are not recollections of our past but rather predictions of the future. As such, memories are evolving constructs prone to modifications....
-
Synaptic Tagging in the ACC: Basic Mechanisms and Functional Implications
Synaptic tagging and capture (STC) is believed to play important roles in hippocampus-related associative memory. Recent studies in the anterior...
-
Synaptic Tagging and Capture: Functional Implications and Molecular Mechanisms
This chapter introduces the concept of synaptic tagging and capture, which was first identified in electrophysiological studies in hippocampal brain...
-
From Where? Synaptic Tagging Allows the Nucleus Not to Care
Most of us now accept that the formation of long-lasting memories requires the de novo transcription of plasticity-related proteins. It is also...
-
Positron Emission Tomography Imaging of Synaptic Dysfunction in Parkinson’s Disease
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases with a complex pathogenesis. Aggregations formed by abnormal deposition...
-
SNARE Proteins in Synaptic Vesicle Fusion
Neurotransmitters are stored in small membrane-bound vesicles at synapses; a subset of synaptic vesicles is docked at release sites. Fusion of docked...
-
Sustained Depolarization Induces Gene Expression Pattern Changes Related to Synaptic Plasticity in a Human Cholinergic Cellular Model
Neuronal gene expression in the brain dynamically responds to synaptic activity. The interplay among synaptic activity, gene expression, and synaptic...
-
Secreted Glycoproteins That Regulate Synaptic Function: the Dispatchers in the Central Nervous System
Glycoproteins are proteins that contain oligosaccharide chains. As widely distributed functional proteins in the body, glycoproteins are essential...
