Search
Search Results
-
Evidences That Sympathetic Overactivity and Neurogenic Hypertension Correlate with Changes in the Respiratory Pattern in Rodent Models of Experimental Hypoxia
The main question of this chapter is as follows: What is the contribution of changes in the sympathetic-respiratory coupling to the hypertension...
-
Central Control of Sympathetic and Renin Angiotensin System in the Development of Hypertension
There is now ample evidence to suggest that many diseases are accompanied by chronic elevations of central sympathetic and renin angiotensin...
-
Blockade of sympathetic ganglia improves vascular dysfunction in septic shock
Sepsis/septic shock activates the sympathetic nervous system (SNS) to deal with the infection stress. However, an imbalanced or maladaptive response...
-
Impact of Liver Sympathetic Nervous System on Liver Fibrosis and Regeneration After Bile Duct Ligation in Rats
The sympathetic nervous system (SNS) affects many functions of the body. SNS fibers regulate many aspects of liver function, repair, and...
-
The Neuro-cardiac Axis in Arrhythmogenesis: Role and Impact of Autonomic Modulation
The autonomic nervous system consisting of two limbs, the sympathetic and parasympathetic nervous system, plays a key role in the modulation of...
-
The sympathies of the body: functional organization and neuronal differentiation in the peripheral sympathetic nervous system
During the last 30 years, our understanding of the development and diversification of postganglionic sympathetic neurons has dramatically increased....
-
Acute effects of empagliflozin on open-loop baroreflex function and urinary glucose excretion in rats with chronic myocardial infarction
Sodium–glucose cotransporter 2 (SGLT2) inhibitors have exerted cardioprotective effects in clinical trials, but underlying mechanisms are not fully...
-
Pathophysiology of reversible cerebral vasoconstriction syndrome
Reversible cerebral vasoconstriction syndrome (RCVS) is a complex neurovascular disorder being recognized during the past two decades. It is...
-
Botulinum Toxin Treatment of Bladder and Pelvic Disorders
Botulinum toxins blocks the release of neurotransmitters at nerve-muscle junction. Neurotransmitters are chemicals that convey the message of the...
-
β-adrenergic signaling triggers enteric glial reactivity and acute enteric gliosis during surgery
BackgroundEnteric glia contribute to the pathophysiology of various intestinal immune-driven diseases, such as postoperative ileus (POI), a motility...
-
Increased β-adrenergic stimulation augments vascular smooth muscle cell calcification via PKA/CREB signalling
In chronic kidney disease (CKD), hyperphosphatemia promotes medial vascular calcification, a process augmented by osteogenic transdifferentiation of...
-
Influence of body composition and cardiorespiratory fitness on plasma HSP72, norepinephrine, insulin, and glucose responses to an acute aerobic exercise bout performed in the fed state
Being overweight is already considered a metabolic risk factor, which can be overcome by increasing cardiorespiratory fitness (CRF). Acute exercise...
-
The role of the brain renin-angiotensin system in Parkinson´s disease
The renin-angiotensin system (RAS) was classically considered a circulating hormonal system that regulates blood pressure. However, different tissues...
-
Exercise-induced changes in plasma S-Klotho levels are associated with the obtained enhancements of heart rate variability in sedentary middle-aged adults: the FIT-AGEING study
The shed form of the Klotho protein (S-Klotho) is considered a biomarker of longevity, but it is still unknown whether the levels are related to...
-
Inhibition of cGAS in Paraventricular Nucleus Attenuates Hypertensive Heart Injury Via Regulating Microglial Autophagy
Neuroinflammation in the cardiovascular center plays a critical role in the progression of hypertensive heart disease. And microglial autophagy is...
-
Effect of GR205171 on autonomic dysreflexia induced by colorectal distension in spinal cord injured rats
Study designPreclinical pharmacology.
ObjectivesTo determine whether blocking substance P signaling attenuates the hypertension and bradycardia...
-
Quantitative assessment of the central versus peripheral effect of intravenous clonidine using baroreflex equilibrium diagrams
Clonidine is a first-generation central antihypertensive that reduces sympathetic nerve activity (SNA). Although clonidine also exerts peripheral...
-
Vidarabine, an anti-herpes agent, improves Porphyromonas gingivalis lipopolysaccharide-induced cardiac dysfunction in mice
In this work, we examined the involvement of type 5 adenylyl cyclase (AC5) in cardiac dysfunction induced in mice given Porphyromonas gingivalis ...
-
SGLT2 inhibitor as a potential therapeutic approach in hyperthyroidism-induced cardiopulmonary injury in rats
Hyperthyroidism-induced cardiac disease is an evolving health, economic, and social problem affecting well-being. Sodium-glucose cotransporter...
-
The Mechanism of α2 adrenoreceptor-dependent Modulation of Neurotransmitter Release at the Neuromuscular Junctions
α2-Adrenoreceptors (ARs) are main G i -protein coupled autoreceptors in sympathetic nerve terminals and targets for dexmedetomidine (DEX), a widely...
