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Blockade of sympathetic ganglia improves vascular dysfunction in septic shock
Sepsis/septic shock activates the sympathetic nervous system (SNS) to deal with the infection stress. However, an imbalanced or maladaptive response...
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Epigenetic Up-Regulation of ADAMTS4 in Sympathetic Ganglia is Involved in the Maintenance of Neuropathic Pain Following Nerve Injury
Sympathetic axonal sprouting into dorsal root ganglia is a major phenomenon implicated in neuropathic pain, and sympathetic ganglia blockage may...
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The Antinociceptive Effect of Sympathetic Block is Mediated by Transforming Growth Factor β in a Mouse Model of Radiculopathy
Although sympathetic blockade is clinically used to treat pain, the underlying mechanisms remain unclear. We developed a localized microsympathectomy...
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Generation of Functional and Mature Sympathetic Neurons from Human Pluripotent Stem Cells via a Neuroepithelial Route
The sympathetic nervous system (SNS) is a crucial branch of the autonomic nervous system (ANS) that is responsible for regulating visceral function...
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Pathophysiological functions of semaphorins in the sympathetic nervous system
Upon exposure to external stressors, the body senses them and activates the sympathetic nervous system (SNS) to maintain the homeostasis, which is...
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Ultrastructure of dorsal root ganglia
Dorsal root ganglia (DRG) contains thousands of sensory neurons that transmit information about our external and internal environment to the central...
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Prion type 2 selection in sporadic Creutzfeldt–Jakob disease affecting peripheral ganglia
In sporadic Creutzfeldt–Jakob disease (sCJD), the pathological changes appear to be restricted to the central nervous system. Only involvement of the...
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Referred Somatic Hyperalgesia Mediates Cardiac Regulation by the Activation of Sympathetic Nerves in a Rat Model of Myocardial Ischemia
Myocardial ischemia (MI) causes somatic referred pain and sympathetic hyperactivity, and the role of sensory inputs from referred areas in cardiac...
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Enteric Control of the Sympathetic Nervous System
The autonomic nervous system that regulates the gut is divided into sympathetic (SNS), parasympathetic (PNS), and enteric nervous systems (ENS). They...
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Sympathetic innervation of human and porcine spleens: implications for between species variation in function
BackgroundThe vagus nerve affects innate immune responses by activating spleen-projecting sympathetic neurons, which modulate leukocyte function....
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Studies of the Dynamics of Transmitter Contents in Neurons in the Sympathetic Ganglia in Cats in Early Ontogeny
Objectives. To determine the location and immunohistochemical characteristics of neurons in the superior cervical (SCG) and stellate (CG) ganglia of...
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The sympathetic nervous system in development and disease
The sympathetic nervous system prepares the body for ‘fight or flight’ responses and maintains homeostasis during daily activities such as exercise,...
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Central Control of Sympathetic and Renin Angiotensin System in the Development of Hypertension
There is now ample evidence to suggest that many diseases are accompanied by chronic elevations of central sympathetic and renin angiotensin...
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Acute Effect of Selective Chemical Inactivation of Sympathetic or Parasympathetic Atrial Ganglionated Plexus Structures on Atrial Fibrillation Inducibility in Pigs
We studied the role of both parts of the autonomic intracardiac nervous system in the pathogenesis of atrial fibrillation (AF). In 12 pigs weighing...
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Enteric glia: extent, cohesion, axonal contacts, membrane separations and mitochondria in Auerbach’s ganglia of guinea pigs
Studied by electron microscopy and morphometry, Auerbach’s ganglia comprise nerve cell bodies that occupy ~ 40% of volume; of the neuropil, little...
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The sympathies of the body: functional organization and neuronal differentiation in the peripheral sympathetic nervous system
During the last 30 years, our understanding of the development and diversification of postganglionic sympathetic neurons has dramatically increased....
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Changes of the Expression of Neuronal NO-Synthase in Rat Sympathetic Ganglia during Ontogeny
Expression of neuronal NO synthase in the sympathetic cranial cervical ganglion and stellate ganglion in rats during postnatal ontogeny was studied...
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Pathophysiological significance of increased α-synuclein deposition in sympathetic nerves in Parkinson’s disease: a post-mortem observational study
BackgroundParkinson’s disease (PD) is characterized by intra-neuronal deposition of the protein α-synuclein (α-syn) and by deficiencies of the...
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The diversity of neuronal phenotypes in rodent and human autonomic ganglia
Selective sympathetic and parasympathetic pathways that act on target organs represent the terminal actors in the neurobiology of homeostasis and...
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Maintenance of contractile force of the hind limb muscles by the somato-lumbar sympathetic reflexes
This study aimed to clarify whether the reflex excitation of muscle sympathetic nerves induced by contractions of the skeletal muscles modulates...
