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Symmetric inheritance of parental histones contributes to safeguarding the fate of mouse embryonic stem cells during differentiation
Parental histones, the carriers of posttranslational modifications, are deposited evenly onto the replicating DNA of sister chromatids in a process...
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Symmetric inheritance of parental histones governs epigenome maintenance and embryonic stem cell identity
Modified parental histones are segregated symmetrically to daughter DNA strands during replication and can be inherited through mitosis. How this may...
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Fragmentation of Different Calcification Growth Patterns in Bicuspid Valves During Balloon Valvuloplasty Procedure
This study focuses on the calcification development and routes of type-1 bicuspid aortic valves based on CT scans and the effect of the unique...
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Shear Histories Alter Local Shear Effects on Thrombus Nucleation and Growth
Our goal was to determine the impact of physiological and pathological shear histories on platelet nucleation and thrombus growth at various local...
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PRMT5 confers lipid metabolism reprogramming, tumour growth and metastasis depending on the SIRT7-mediated desuccinylation of PRMT5 K387 in tumours
The protein arginine methyltransferase 5 (PRMT5), which is highly expressed in tumour tissues, plays a crucial role in cancer development. However,...
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Brain-Derived Neurotrophic Factor and Vascular Endothelial Growth Factor A: Biomarkers Potential in Diabetes
Previously, brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF) have been studied only in diabetic neuropathy or...
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3q27.1 microdeletion causes prenatal and postnatal growth restriction and neurodevelopmental abnormalities
BackgroundOverlap** microdeletions of chromosome 3q26-3q28 have been reported in eight individuals. The common phenotype observed in these...
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Brain-derived neurotrophic factor and vascular endothelial growth factor A: biomarkers potential in diabetes
Previously, brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF) have been studied only in diabetic neuropathy or...
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The effect of recombinant human epidermal growth factor on radiation dermatitis in rectal and anal cancer patients: a self-controlled study
BackgroundOur previous study reported that recombinant human epidermal growth factor (rhEGF)-triggered EGFR internalization promoted radioresistance....
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DNA-Generated Electric Current Biosensor for Epidermal Growth Factor Receptor 2 (HER2) Analysis
Electrochemical biosensors have been applied in the detection of human serum biomarkers for clinical applications. A kind of signal amplifying method...
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Sex- and growth-specific characteristics of small for gestational age infants: a prospective cohort study
BackgroundAsymmetric fetal growth and male sex are both associated with adverse neonatal outcome. However, less is known about the influence of...
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YWHAH Genetic Variants are Associated with Increased Hypoxia Inducible Factor-1α/Vascular Endothelial Growth Factor in Egyptian Rheumatoid Arthritis Patients
The 14–3-3 Eta (14–3-3 η) biomarker platform is a relatively recent discovery with the potential to significantly address the diagnosis and prognosis...
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A Novel Group Decision-Making Method Based on Linguistic Neutrosophic Maclaurin Symmetric Mean (Revision IV)
Linguistic neutrosophic number (LNN) is a specific form of neutrosophic number whose elements are expressed by linguistic terms. Maclaurin symmetric...
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Origin and Development of Cancer Stem Cells
Cancer stem cells (CSCs) have been identified in a vast number of liquid and solid tumors and have been linked to poor patient prognosis and cancer...
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Machine learning-based classification of dual fluorescence signals reveals muscle stem cell fate transitions in response to regenerative niche factors
The proper regulation of muscle stem cell (MuSC) fate by cues from the niche is essential for regeneration of skeletal muscle. How pro-regenerative...
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The expression of tenascin-C in neural stem/progenitor cells is stimulated by the growth factors EGF and FGF-2, but not by TGFβ1
Neural stem/progenitor cells (NSPCs) rely on internal and external cues determining their lineage decisions during brain development. The progenitor...
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Depletion of transit amplifying cells in the adult brain does not affect quiescent neural stem cell pool size
Neural stem cells (NSCs) are maintained in the adult mammalian brain throughout the animal’s lifespan. NSCs in the subependymal zone infrequently...
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Cancer Stem Cells in Cancer Initiation and Progression
Cancer stem cells (CSCs) are a subclass of cancer cells that can differentiate into various cell types and self-renew, similar to normal stem cells....
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Molecular Pathways and Animal Models of Defects in Situs
Left–right patterning is among the least well understood of the three axes defining the body plan, and yet it is no less important, with left–right...
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Evaluation of the Stress–Growth Hypothesis in Saphenous Vein Perfusion Culture
The great saphenous vein (GSV) has served as a coronary artery bypass graft (CABG) conduit for over 50 years. Despite prevalent use, first-year...
