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Prophages Preventing Phage Superinfection
One means by which prophages can modify bacterial phenotypes is by protecting lysogens from infections by additional phages. In part this protection...
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Analysis of PERV-C superinfection resistance using HA-tagged viruses
BackgroundUsing pigs as organ donors has advanced xenotransplantation to the point that it is almost ready for clinical use. However, there is still...
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Resurgence of SARS-CoV-2 Delta after Omicron variant superinfection in an immunocompromised pediatric patient
BackgroundPersistent SARS-CoV-2 infection in immunocompromised hosts is thought to contribute to viral evolution by facilitating long-term natural...
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Model of vaccine efficacy against HSV-2 superinfection of HSV-1 seropositive mice demonstrates protection by antibodies mediating cellular cytotoxicity
A majority of the world’s population is infected with HSV-1, highlighting the need for vaccines that are effective in HSV-1-seropositive hosts. We...
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Evaluating the performance of Plasmodium falciparum genetic metrics for inferring National Malaria Control Programme reported incidence in Senegal
BackgroundGenetic surveillance of the Plasmodium falciparum parasite shows great promise for hel** National Malaria Control Programmes (NMCPs)...
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Co-infection, reinfection and superinfection with Anaplasma phagocytophilum strains in a cattle herd based on ankA gene and multilocus sequence ty**
BackgroundAnaplasma phagocytophilum is a Gram-negative obligate intracellular bacterium that replicates in neutrophil granulocytes. It is...
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The brain reacting to COVID-19: analysis of the cerebrospinal fluid proteome, RNA and inflammation
Patients with COVID-19 can have a variety of neurological symptoms, but the active involvement of central nervous system (CNS) in COVID-19 remains...
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Resistance to Phages , Part I: Overview
Phages can decrease the fitness of infected bacteria, as is most obviously seen with phage lyticLytic cycles. This as a consequence can result in...
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Distinct mechanisms of long-term virologic control in two HIV-infected individuals after treatment interruption of anti-retroviral therapy
Certain infected individuals suppress human immunodeficiency virus (HIV) in the absence of anti-retroviral therapy (ART). Elucidating the underlying...
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Resistance to Phages , Part II: Bacteria Live!
Acquired resistance to phage infections that retain bacterial survival can be differentiated into those acting prior to the delivery of phage DNA...
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Analysis of HIV quasispecies and virological outcome of an HIV D+/R+ kidney–liver transplantation
IntroductionTransplantation among HIV positive patients may be a valuable therapeutic intervention. This study involves an HIV D+/R+ kidney–liver...
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COVID-19 and spinal cord injury: clinical presentation, clinical course, and clinical outcomes of people hospitalised
Study designRetrospective study
ObjectivesTo describe the presenting symptoms/signs, clinical course and outcomes in hospitalised people with spinal...
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Impact of rapid multiplex PCR on management of antibiotic therapy in COVID-19-positive patients hospitalized in intensive care unit
Because the diagnosis of co/superinfection in COVID-19 patients is challenging, empirical antibiotic therapy is frequently initiated until...
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Morbidity of Scabies in Resource-Limited Countries: Rheumatic Heart Disease (RHD) and Post-Streptococcal Glomerulonephritis (APSGN)
Scabies is one of the world’s most prevalent diseases, with approximately 147 million cases at any one time and an estimated annual incidence of 455...
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Dalbavancin as suppressive therapy for implant-related infections: a case series with therapeutic drug monitoring and review of the literature
Implant-related infections may need suppressive antibiotic therapy (SAT). We describe a SAT strategy using dalbavancin with therapeutic drug...
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Bacterial and fungal growth in sputum cultures from 165 COVID-19 pneumonia patients requiring intubation: evidence for antimicrobial resistance development and analysis of risk factors
BackgroundCoronavirus SARS-CoV-2 causes COVID-19 illness which can progress to severe pneumonia. Empiric antibacterials are often employed though...
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Prion Strain Interference
Prions are transmissible agents comprised of a misfolded protein PrPSc that is post-translationally derived from the normal isoform PrPC. Prion...
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Scabies in Infants and Children
Clinical presentation of scabies varies according to age. Scabies in infants and children shared specific signs on preferential locations...
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Poxviridae Pneumonia
Poxviridae family includes several viruses that infecting humans usually causes skin lesions only, but in some cases their clinical course is...
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Microorganisms in Pathogenesis and Management of Atopic Dermatitis
Atopic dermatitis is a very common skin disease, with increasing incidence in Europe and North America, where it represents a heavy burden for...