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Development and validation of a short-form suboptimal health status questionnaire
BackgroundSuboptimal health status (SHS) is a reversible, borderline state between optimal health and disease. Although this condition’s definition...
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The mediating effect of perceived stress on the relationship between big five personality traits and suboptimal health status in Chinese population: a nationwide survey in the framework of predictive, preventive, and personalized medicine
BackgroundThe effects of psychological factors on suboptimal health status (SHS) have been widely described; however, mechanisms behind the complex...
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Glycomic biomarkers are instrumental for suboptimal health status management in the context of predictive, preventive, and personalized medicine
ObjectivesSuboptimal health status (SHS), a reversible borderline condition between optimal health status and disease, has been recognized as a main...
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Conceptualised psycho-medical footprint for health status outcomes and the potential impacts for early detection and prevention of chronic diseases in the context of 3P medicine
BackgroundThe Suboptimal Health Status Questionnaire-25 (SHSQ-25) is a distinctive medical psychometric diagnostic tool designed for the early...
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All around suboptimal health — a joint position paper of the Suboptimal Health Study Consortium and European Association for Predictive, Preventive and Personalised Medicine
First two decades of the twenty-first century are characterised by epidemics of non-communicable diseases such as many hundreds of millions of...
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Blood transcriptome profiling as potential biomarkers of suboptimal health status: potential utility of novel biomarkers for predictive, preventive, and personalized medicine strategy
The early identification of Suboptimal Health Status (SHS) creates a window opportunity for the predictive, preventive, and personalized medicine...
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Early gestational profiling of oxidative stress and angiogenic growth mediators as predictive, preventive and personalised (3P) medical approach to identify suboptimal health pregnant mothers likely to develop preeclampsia
BackgroundP regnant women, particularly in develo** countries are facing a huge burden of preeclampsia (PE) leading to high morbidity and mortality...
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Psychological symptoms in Chinese nurses may be associated with predisposition to chronic disease: a cross-sectional study of suboptimal health status
BackgroundSuboptimal health status (SHS) is a reversible state between ideal health and illness and it can be effectively reversed by risk...
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The Rapidly Expanding Nexus of Immunoglobulin G N-Glycomics, Suboptimal Health Status, and Precision Medicine
Immunoglobulin G is a prevalent glycoprotein, whose downstream immune responses are partially mediated by the N-glycans within the fragment...
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Association of IgG N-glycomics with prevalent and incident type 2 diabetes mellitus from the paradigm of predictive, preventive, and personalized medicine standpoint
ObjectivesType 2 diabetes mellitus (T2DM), a major metabolic disorder, is expanding at a rapidly rising worldwide prevalence and has emerged as one...
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Population-based case-control study revealed metabolomic biomarkers of suboptimal health status in Chinese population—potential utility for innovative approach by predictive, preventive, and personalized medicine
BackgroundSuboptimal health status (SHS) is a subclinical stage of chronic diseases, and the identification of SHS provides an opportunity for the...
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Suboptimal Health Status and Cardiovascular Deficits
Suboptimal Health Status (SHS) is the subclinical, reversible stage of pre-chronic disease. It is the physical state between health and disease,...
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Integration of suboptimal health status evaluation as a criterion for prediction of preeclampsia is strongly recommended for healthcare management in pregnancy: a prospective cohort study in a Ghanaian population
BackgroundNormotensive pregnancy may develop into preeclampsia (PE) and other adverse pregnancy complications (APCs), for which the causes are still...
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Suboptimal health status as an independent risk factor for type 2 diabetes mellitus in a community-based cohort: the China suboptimal health cohort study
BackgroundThe prevalence of diabetes, constituted chiefly by type 2 diabetes mellitus (T2DM), is a global public health threat. Suboptimal health...
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Suboptimal health status and psychological symptoms among Chinese college students: a perspective of predictive, preventive and personalised health
BackgroundSuboptimal health status (SHS) is an intermediate health status between health and illness, a syndrome characterised by the perception of...
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Air Pollution and Perinatal Health in the Eastern Mediterranean Region: Challenges, Limitations, and the Potential of Epigenetics
Purpose of ReviewEven though the burden of disease attributable to air pollution is high in the Eastern Mediterranean Region (EMR), the number of...
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Latent class analysis to evaluate performance of plasma cortisol, plasma catecholamines, and SHSQ-25 for early recognition of suboptimal health status
BackgroundChronic stress is associated with suboptimal health status (SHS) which is a new public health challenge in China and worldwide. Plasma...
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A nomogram model for the risk prediction of type 2 diabetes in healthy eastern China residents: a 14-year retrospective cohort study from 15,166 participants
BackgroundRisk prediction models can help identify individuals at high risk for type 2 diabetes. However, no such model has been applied to clinical...
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Effectiveness and feasibility of the workout on wheels internet intervention (WOWii) for individuals with spinal cord injury: a randomized controlled trial
Study designRandomized-controlled trial (RCT) with immediate intervention (IMM) and wait-list control (WLC) groups; WLC participants received the...
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Incorporation of suboptimal health status as a potential risk assessment for type II diabetes mellitus: a case-control study in a Ghanaian population
Due to a paradigm shift in lifestyles, there is growing concern that type 2 diabetes mellitus (T2DM) will reach epidemic proportions in Ghana....