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A Millifluidic Chamber for Controlled Shear Stress Testing: Application to Microbial Cultures
In vitro platforms such as bioreactors and microfluidic devices are commonly designed to engineer tissue models as well as to replicate the crosstalk...
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Testing of Medical Devices
Medical device testing plays a vital role in ensuring the safety, efficacy, and quality of medical devices before they are introduced to the market....
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The role of estrogen receptor manipulation during traumatic stress on changes in emotional memory induced by traumatic stress
RationaleTraumatic stress leads to persistent fear, which is a core feature of post-traumatic stress disorder (PTSD). Women are more likely than men...
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Sex-dependent effects of acute stress in adolescence or adulthood on appetitive motivation
RationaleIntensely stressful experiences can lead to long-lasting changes in appetitive and aversive behaviors. In humans, post-traumatic stress...
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Preanalytical Variables in Hemostasis Testing
Hemostasis testing performed in clinical laboratories are critical for assessing hemorrhagic and thrombotic disorders. The assays performed can be...
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Establishment of a Biaxial Testing System for Characterization of Right Ventricle Viscoelasticity Under Physiological Loadings
PurposePrior studies have indicated an impact of cardiac muscle viscoelasticity on systolic and diastolic functions. However, the studies of...
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The value of genomic testing in severe childhood speech disorders
With increasing gene discoveries for severe speech disorders, genomic testing can alter the diagnostic and clinical paradigms, enabling better life...
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FOXA1 Suppresses Endoplasmic Reticulum Stress, Oxidative Stress, and Neuronal Apoptosis in Parkinson's Disease by Activating PON2 Transcription
Endoplasmic reticulum (ER) stress and oxidative stress (OS) are often related states in pathological conditions including Parkinson's disease (PD)....
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Animal DNA Testing
Animal DNA can play a key role in poaching, illegal trafficking, and crimes involving animal products. DNA from nonhuman sources can be more prone to...
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Stress-Induced Visceral Analgesia: Concept and Pathways
Decades of research in the somatic pain field have established that stress has a major influence on pain modulation affecting it in two opposite...
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Mutagenic Toxicity Testing
Genetic toxicology is a subspecialty of toxicology, which deals with identification, testing and analysis of substances which can cause damage to...
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Bone Plates Runout Prediction Through Tensile Strength and Geometric Properties for Regulatory Mechanical Testing
Mechanical tests on bone plates are mandatory for regulatory purposes and, typically, the ASTM F382 standard is used, which involves a four-point...
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Greek Adaptation and Validation of the Bad Sobernheim Stress Questionnaire-Brace and the Bad Sobernheim Stress Questionnaire-Deformity
Adolescent idiopathic scoliosis (AIS) is a progressive condition responsible for spinal deformity in all three planes. Spinal deformity and how the...
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Testing Prepulse Inhibition of Acoustic Startle in Rodents
Prepulse inhibition (PPI) is a measure of sensorimotor gating which is widely used in rodents to study information processing and attention...
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Identification of the role of endoplasmic reticulum stress genes in endometrial cancer and their association with tumor immunity
BackgroundEndometrial cancer (EC) is one of the worldwide gynecological malignancies. Endoplasmic reticulum (ER) stress is the cellular homeostasis...
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Positron emission tomography imaging of the sodium iodide symporter senses real-time energy stress in vivo
BackgroundTissue environment is critical in determining tumour metabolic vulnerability. However, in vivo drug testing is slow and waiting for tumour...
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High-Throughput SARS-CoV-2 Antiviral Testing Method Using the Celigo Image Cytometer
The COVID-19 pandemic has created a worldwide public health crisis that has since resulted in 6.8 million reported deaths. The pandemic prompted the...
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Patient perspectives on pharmacogenomic (PGx) testing for antidepressant prescribing in primary care: a qualitative description study
Many patients with major depressive disorder (MDD) try multiple antidepressants before finding one that works well and is tolerable. Pharmacogenomic...
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Review of Psychophysiological and Psychotherapeutic Studies of Stress Using Virtual Reality Technologies
This review addresses the use of virtual reality technologies in the psychophysiology and psychotherapy of stress. Studies using virtual reality both...
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Epigenetics of prenatal stress in humans: the current research landscape
Fetal exposure to prenatal stress can have significant consequences on short- and long-term health. Epigenetic mechanisms, especially DNA methylation...
