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Long-term stability of single neuron activity in the motor system
How an established behavior is retained and consistently produced by a nervous system in constant flux remains a mystery. One possible solution to...
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Dissociating the contributions of sensorimotor striatum to automatic and visually guided motor sequences
The ability to sequence movements in response to new task demands enables rich and adaptive behavior. However, such flexibility is computationally...
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Temporal scaling of motor cortical dynamics reveals hierarchical control of vocal production
Neocortical activity is thought to mediate voluntary control over vocal production, but the underlying neural mechanisms remain unclear. In a highly...
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Motor Circuit Abnormalities During Cerebellar Development
The cerebellum controls ongoing motor function and motor learning. Therefore, damage to its circuits causes a number of movement disorders such as... -
MeCP2 deficiency impairs motor cortical circuit flexibility associated with motor learning
Loss of function mutations in the X-linked gene encoding methyl-CpG binding protein 2 (MECP2) cause Rett syndrome (RTT), a postnatal neurological...
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Pedunculopontine Chx10+ neurons control global motor arrest in mice
Arrest of ongoing movements is an integral part of executing motor programs. Behavioral arrest may happen upon termination of a variety of...
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Disorders of Motor Activity in a Model of Autism Spectrum Disorders
Autism, or autism spectrum disorder (ASD), is a multifactorial disease characterized not only by disturbances in psychoemotional status and social...
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Converging and Diverging Cerebellar Pathways for Motor and Social Behaviors in Mice
Evidence from clinical and preclinical studies has shown that the cerebellum contributes to cognitive functions, including social behaviors. Now that...
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Recovery of Motor and Cognitive Functions on Forced Waking from Stage 3 Daytime Sleep
The mechanisms of behavioral recovery of various forms on waking from sleep are still not well understood. We report here studies of the recovery of...
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Triple dissociation of visual, auditory and motor processing in mouse primary visual cortex
Primary sensory cortices respond to crossmodal stimuli—for example, auditory responses are found in primary visual cortex (V1). However, it remains...
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Motor networks in children with autism spectrum disorder: a systematic review on EEG studies
Motor disturbance and altered motor networks are commonly reported in individuals with autism spectrum disorder (ASD). It has been suggested that...
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Excitatory nucleo-olivary pathway shapes cerebellar outputs for motor control
The brain generates predictive motor commands to control the spatiotemporal precision of high-velocity movements. Yet, how the brain organizes...
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Video polysomnographic analysis of elevated EMG activity and rapid eye movements before abnormal behaviors in REM sleep behavior disorder
The pathogenesis of rapid eye movement (REM) sleep behavior disorder (RBD) is unclear. According to the cortical hypothesis, severe RBD episode...
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Intestinal Microbiota Is a Key Target for Load Swimming to Improve Anxiety Behavior and Muscle Strength in Shank 3-/- Rats
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social disorder and stereotypical behavior, and its incidence rate...
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Perceptual-motor styles
Even for a stereotyped task, sensorimotor behavior is generally variable due to noise, redundancy, adaptability, learning or plasticity. The sources...
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Evaluation of Sexual Behavior in Laboratory vs Seminatural Conditions
Sexual behavior is, by necessity, sexually dimorphic. Males transfer sperm to females, whereas females receive sperm from males. Discussions of sex... -
The basal ganglia control the detailed kinematics of learned motor skills
The basal ganglia are known to influence action selection and modulation of movement vigor, but whether and how they contribute to specifying the...
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Neuromodulation with transcutaneous spinal stimulation reveals different groups of motor profiles during robot-guided step** in humans with incomplete spinal cord injury
Neuromodulation via spinal stimulation has been investigated for improving motor function and reducing spasticity after spinal cord injury (SCI) in...
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Behavioral Presentation of Sleep-Related Motor Disorders
Sleep-related movement disorders, for example, restless legs syndrome and sleep related bruxism, interfere with acquisition of good quality sleep.... -
Comparative neurogenetics of dog behavior complements efforts towards human neuropsychiatric genetics
Domestic dogs display a wide array of heritable behaviors that have intermediate genetic complexity thanks to a long history of human-influenced...