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The Microbiome and Infectious Disease
Microbial communities (microbiota) are integral parts of multicellular eukaryotes that profoundly affect immunity and health. The microbiome includes...
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Metabolic modeling of the International Space Station microbiome reveals key microbial interactions
BackgroundRecent studies have provided insights into the persistence and succession of microbes aboard the International Space Station (ISS), notably...
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The Gut Microbiome and Residential Surrounding Greenness: a Systematic Review of Epidemiological Evidence
Purpose of ReviewA healthy indigenous intestinal microbiome is essential for human health. Well-established gut microbiome determinants only explain...
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The Gut Microbiome, Microbial-Produced Pro-inflammatory Neurotoxins, and Neurological Disorders
The gut microbiome is now recognized as a crucial determinant of human health and diseases, and it has been increasingly implicated in the...
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Molecular Interplay of Oxidative Stress and Gut Microbiome in Aging
Oxidative stress results from an imbalance between reactive oxygen species production and the capacity of the organism to counteract them. These...
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Machine learning algorithm to characterize antimicrobial resistance associated with the International Space Station surface microbiome
BackgroundAntimicrobial resistance (AMR) has a detrimental impact on human health on Earth and it is equally concerning in other environments such as...
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Longitudinal gut microbiome changes in immune checkpoint blockade-treated advanced melanoma
Multiple clinical trials targeting the gut microbiome are being conducted to optimize treatment outcomes for immune checkpoint blockade (ICB). To...
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Microbiome and Big-Data Mining
Microbiome samples are accumulating at a very fast speed, representing microbial communities from every niche (biome) of our body as well as the...
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Model-free prediction of microbiome compositions
BackgroundThe recent recognition of the importance of the microbiome to the host’s health and well-being has yielded efforts to develop therapies...
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Relative abundance data can misrepresent heritability of the microbiome
BackgroundHost genetics can shape microbiome composition, but to what extent it does, remains unclear. Like any other complex trait, this important...
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Alternative stable states, nonlinear behavior, and predictability of microbiome dynamics
BackgroundMicrobiome dynamics are both crucial indicators and potential drivers of human health, agricultural output, and industrial...
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Urinary microbiome-based metagenomic signature for the noninvasive diagnosis of hepatocellular carcinoma
BackgroundGut microbial dysbiosis is implicated in chronic liver disease and hepatocellular carcinoma (HCC), but the role of microbiomes from various...
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Cardiometabolic health, diet and the gut microbiome: a meta-omics perspective
Cardiometabolic diseases have become a leading cause of morbidity and mortality globally. They have been tightly linked to microbiome taxonomic and...
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Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer
Human papillomavirus can cause preinvasive, high-grade squamous intraepithelial lesions (HSILs) as precursors to cancer in the anogenital area, and...
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Immunity to Bacterial Pathogens and the Microbiome
In this chapter, we will learn that the major physiological function of the immune system is the protection of our body against microbe infections....
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Microbiome Data Analysis and Interpretation: Correlation Inference and Dynamic Pattern Discovery
Microbial communities are everywhere within our bodies and in the environments (Byrd et al. n.d.), which play a key role in human health and all...
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Microbiome epidemiology and association studies in human health
Studies of the human microbiome share both technical and conceptual similarities with genome-wide association studies and genetic epidemiology....
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Kernel-based genetic association analysis for microbiome phenotypes identifies host genetic drivers of beta-diversity
BackgroundUnderstanding human genetic influences on the gut microbiota helps elucidate the mechanisms by which genetics may influence health...
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The Microbiome of the Human Eye
Microbiome refers to the community of bacteria, fungi and viruses that are associated with our body. The most studied is the microbiome of the human...
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An integrated tumor, immune and microbiome atlas of colon cancer
The lack of multi-omics cancer datasets with extensive follow-up information hinders the identification of accurate biomarkers of clinical outcome....
