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Repurposing of Drugs in Aging
Aging is a complex biological process characterized by a gradual decline in physiological functions and an increased susceptibility to age-related...
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The Process of Drug Development from Natural Sources
The history of drug discovery and development is deeply knotted with human civilization. Early humans, driven by curiosity and the need for survival,...
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Drugs from Nature: Targets, Assay Systems and Leads
This book provides an overview of the drug discovery process from natural sources such as plants and microbes. While technological advances have...
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Cardiotoxicity of HER2-Targeted Drugs When Combined with Other Drugs: A Systematic and Meta-analysis of Randomized Controlled Trials
The development and use of HER2-targeted drugs has improved the prognosis of HER2-positive cancer patients. However, in addition to improved survival...
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Drug Discovery from Natural Sources
Purpose of ReviewA discussion of the role of natural products as drugs and/or following partial or complete chemical synthesis, have been approved...
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Drugs Affecting Gastrointestinal Functions
The digestive system in humans is the mechanism that the body uses to carry out digestion. Food is ingested by the digestive system, which is...
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Nonsteroidal Anti-Inflammatory Drug Leads from Plant Sources
Nonsteroidal anti-inflammatory drugs are FDA-approved for their anti-inflammatory, antipyretic (fever-reducing), and analgesic (pain-relieving)...
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Drugs Acting on Renal and Cardiovascular Function
Cardiovascular medications play a crucial role in medical practice by influencing the functionality of the heart and blood vessels. These medications...
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Drugs of Abuse: Trends and Advanced Analytical Methods
Abuse of drugs is correlated with various medical, behavioral, psychological, spiritual, financial, social, family, and legal concerns and profoundly...
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Relative Performance of Volume of Distribution Prediction Methods for Lipophilic Drugs with Uncertainty in LogP Value
PurposeThe goal was to assess, for lipophilic drugs, the impact of logP on human volume of distribution at steady-state (VD ss ) predictions,...
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Drugs from Nature: Targets, Assay Systems, and Leads
The overview is done to determine whether the era of natural products for drug discovery is over or not over. Though the drug discovery process is...
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Foreign Compounds: Foods, Drugs, Chemicals, and Lifestyles
Foods are substances that contain essential nutrients such as proteins, carbohydrates...
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Role of Artificial Intelligence in the Toxicity Prediction of Drugs
Therapeutic drugs are meant for treating the diseases, unfortunately, these drugs also possess unwanted adverse effects due to drug-drug interactions...
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Safety analysis of therapeutic drugs for breast cancer patients and construction of a predictive model for serious adverse drug reactions
ObjectivesTo explore the characteristics of the occurrence of antineoplastic drug adverse reactions (ADRs) in breast cancer and to utilize a...
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Progress in the Development of Fungal Metabolites as New Drugs for Human Mycoses
Fungi have a fascinating track record related to producing bioactive substances that have become medicines or inspired the synthesis of drug leads....
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Comparison of different sources of mesenchymal stem cells: focus on inflammatory bowel disease
Inflammatory bowel disease (IBD) poses a significant challenge in modern medicine, with conventional treatments limited by efficacy and associated...
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Cardiovascular Therapeutics from Natural Sources
Cardiovascular diseases (CVDs) are a group of heart and blood vessel disorder. It is a persistent global health challenge, being the number one cause...
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Digestive enzyme supplementation in prescription drugs, over-the-counter drugs, and enzyme foods
BackgroundDigestive enzyme supplements are used in various fields, including prescription drugs, over-the-counter drugs, and enzyme foods, but few...
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Enzymatic Sources of Free Radicals
Though reading the previous chapters on molecular mechanisms of ultraweak photon emission (UPE), you may have felt that you understand all the...
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Effects of Current Psychotropic Drugs on Inflammation and Immune System
The immune system and inflammation are involved in the pathological progression of various psychiatric disorders such as depression or major...