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Tau seeding activity in skin biopsy differentiates tauopathies from synucleinopathies
Most neurodegenerative diseases lack definitive diagnostic tests, and the identification of easily accessible and reliable biomarkers remains a...
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A comparative blind study between skin biopsy and seed amplification assay to disclose pathological α-synuclein in RBD
To compare the diagnostic accuracy of the immunofluorescence (IF) technique and aSyn-seed amplification assay (aSyn-SAA) of skin and cerebrospinal...
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Prophylactic antimicrobials may not be needed to prevent surgical site infection after skin biopsy: a retrospective study
BackgroundTwo types of skin biopsies are routinely performed in dermatology: excisional and punch biopsies. A punch biopsy is a relatively low-risk...
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Deep learning-aided decision support for diagnosis of skin disease across skin tones
Although advances in deep learning systems for image-based medical diagnosis demonstrate their potential to augment clinical decision-making, the...
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Skin Cancer: An Overview
Skin cancer is one of the most prevalent forms of cancer, comprising two major types: non-melanoma and melanoma. The major cause behind development...
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A skin-specific α-Synuclein seeding amplification assay for diagnosing Parkinson’s disease
The seeding amplification assay (SAA) has recently emerged as a valuable tool for detecting α-synuclein (αSyn) aggregates in various clinically...
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Atypical skin conditions of the neck and back as a dermal manifestation of anti-HMGCR antibody-positive myopathy
BackgroundImmune-mediated necrotizing myopathy (IMNM) is an idiopathic inflammatory myopathy (IIM). Though patients with IMNM were not considered to...
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Skin Pharmacology
Percutaneous absorption assays assess the safety of substances that may contact the skin, such as topical medications, skin/hair care products,...
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A multicenter noninferior randomized controlled study of sentinel lymph node biopsy alone versus sentinel lymph node biopsy plus lymphadenectomy for patients with stage I endometrial cancer, INSEC trial concept
BackgroundUp to the present time, there has remained a lack of strong evidence as to whether sentinel lymph node biopsy can replace lymphadenectomy...
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The Value of Cell-Free Circulating DNA Profiling in Patients with Skin Diseases
Liquid biopsy, also known as fluid biopsy or fluid-phase biopsy, is the sampling and analysis of the blood, cerebrospinal fluid, saliva, pleural...
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Skin Cancer: An Overview
Skin cancer is one of the most prevalent forms of cancer, comprising two major types: non-melanoma and melanoma. The major cause behind development...
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Comprehensive review and expanding the genetic landscape of Cornelia-de-Lange spectrum: insights from novel mutations and skin biopsy in exome-negative cases
BackgroundCornelia de Lange Syndrome (CdLS) is a rare genetic disorder characterized by a range of physical, cognitive, and behavioral abnormalities....
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Path planning for percutaneous lung biopsy based on the loose-Pareto and adaptive heptagonal optimization method
Lung cancer has is highly prevalent worldwide and is the leading cause of cancer-related deaths. In the clinic, a biopsy sample of the lesion is...
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Sentinel Lymph Node Biopsy for Primary Cutaneous Malignancy
Sentinel lymph node biopsy (SLNB) is the international standard of care for providing prognostic information in cutaneous melanoma. This chapter...
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In-Silico Analysis of Optimal Configurations for Rotational Bioinspired Bone Marrow Biopsy Needle Designs: An ANN Approach
Medical needle innovations have utilized rotating motion to enhance tissue-cutting capabilities, reducing cutting force and improving clinical...
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Electroporation-Based Biopsy Treatment Planning with Numerical Models and Tissue Phantoms
Molecular sampling with vacuum-assisted tissue electroporation is a novel, minimally invasive method for molecular profiling of solid lesions. In...
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Liquid biopsy in T-cell lymphoma: biomarker detection techniques and clinical application
T-cell lymphoma is a highly invasive tumor with significant heterogeneity. Invasive tissue biopsy is the gold standard for acquiring molecular data...
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Early detection of pancreatic cancer by liquid biopsy “PANLIPSY”: a french nation-wide study project
BackgroundPancreatic cancer, predominantly characterized by ductal adenocarcinoma (PDAC) accounts for 90% of cases and is the fourth leading cause of...
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Skin Cancer: Prevention and Early Detection
Melanoma and non-melanoma skin cancers are one of the most common cancers prevalent in white-skinned populations, and its rising incidence and...