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Short-chain fatty acids: linking diet, the microbiome and immunity
The short-chain fatty acids (SCFAs) butyrate, propionate and acetate are microbial metabolites and their availability in the gut and other organs is...
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The Role of Gut-derived Short-Chain Fatty Acids in Multiple Sclerosis
Multiple sclerosis (MS) is a chronic condition affecting the central nervous system (CNS), where the interplay of genetic and environmental factors...
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Relationship Between Short-chain Fatty Acids and Parkinson’s Disease: A Review from Pathology to Clinic
Parkinson’s disease (PD) is a complicated neurodegenerative disease, characterized by the accumulation of α-synuclein (α-syn) in Lewy bodies and...
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Changes of the Concentration of Short-Chain Fatty Acids in the Intestines of Mice with Different Types of Obesity
We studied the production of short-chain fatty acids (SCFA) by the intestinal microbiota in mice with obesity caused by a diet and a genetic defect...
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Short-chain fatty acids in cancer pathogenesis
Cancer is a multi-step process that can be viewed as a cellular and immunological shift away from homeostasis in response to selected infectious...
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Complex regulatory effects of gut microbial short-chain fatty acids on immune tolerance and autoimmunity
Immune tolerance deletes or suppresses autoreactive lymphocytes and is established at multiple levels during the development, activation and effector...
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Bioinformatics Approach to Identify the Pathogenetic Link of Gut Microbiota-Derived Short-Chain Fatty Acids and Ischemic Stroke
Stroke is a life-threatening condition that impairs the arteries and causes neurological impairment. The incidence of stroke is increasing year by...
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Association of fecal short-chain fatty acids with clinical severity and gut microbiota in essential tremor and its difference from Parkinson’s disease
Diagnosis of essential tremor (ET) at an early stage can be difficult, especially when distinguishing it from healthy controls (HCs) and Parkinson’s...
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Plasma Metabolic Analysis Reveals the Dysregulation of Short-Chain Fatty Acid Metabolism in Parkinson’s Disease
Parkinson’s disease (PD) is a progressive neurodegenerative disorder, characterized by high morbidity, high disability rate, and slow course of...
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Short-chain fatty acids ameliorate spinal cord injury recovery by regulating the balance of regulatory T cells and effector IL-17+ γδ T cells
Spinal cord injury (SCI) causes motor, sensory, and autonomic dysfunctions. The gut microbiome has an important role in SCI, while short-chain fatty...
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The Bridge Between Ischemic Stroke and Gut Microbes: Short-Chain Fatty Acids
Short-chain fatty acids (SCFAs) are monocarboxylates produced by the gut microbiota (GM) and result from the interaction between diet and GM. An...
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Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation
Barrier integrity is central to the maintenance of healthy immunological homeostasis. Impaired skin barrier function is linked with enhanced allergen...
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Branched Short-Chain Fatty Acids as Biological Indicators of Microbiota Health and Links with Anthropometry
Bacterial metabolites are one of the main mechanisms of host-microbiota interactions in the gut. Acetate, propionate, and butyrate, also known as... -
Branched Short-Chain Fatty Acids as Biological Indicators of Microbiota Health and Links with Anthropometry
Bacterial metabolites are one of the main mechanisms of host-microbiota interactions in the gut. Acetate, propionate, and butyrate, also known as... -
Sodium butyrate ameliorates diabetic retinopathy in mice via the regulation of gut microbiota and related short-chain fatty acids
BackgroundDiabetic retinopathy (DR) development is associated with disturbances in the gut microbiota and related metabolites. Butyric acid is one of...
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Analysis of correlations between gut microbiota, stool short chain fatty acids, calprotectin and cardiometabolic risk factors in postmenopausal women with obesity: a cross-sectional study
BackgroundMicrobiota and its metabolites are known to regulate host metabolism. In cross-sectional study conducted in postmenopausal women we aimed...
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Omega-6 Fatty Acids
Omega-6 fatty acids are involved in a series of biological processes including inflammation, immune function, and carcinogenesis. Omega-6 fatty acids... -
Role of Short-Chain Fatty Acids from Gut Microbiota in Neuroendocrine Pathogenesis Management
Short-chain fatty acids (SCFAs) are important beneficial molecules produced as a result of microbial fermentation and are currently researched for... -
Omega-6 Fatty Acids
Omega-6 fatty acids are involved in a series of biological processes including inflammation, immune function, and carcinogenesis. Omega-6 fatty acids... -
Short-Chain Fatty Acids Reduce Oligodendrocyte Precursor Cells Loss by Inhibiting the Activation of Astrocytes via the SGK1/IL-6 Signalling Pathway
Short-chain fatty acids (SCFAs) are known to be actively involved in neurological diseases, but their roles in hypoxic-ischaemic brain injury (HIBI)...