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  1. Short-chain fatty acids: linking diet, the microbiome and immunity

    The short-chain fatty acids (SCFAs) butyrate, propionate and acetate are microbial metabolites and their availability in the gut and other organs is...

    Elizabeth R. Mann, Ying Ka Lam, Holm H. Uhlig in Nature Reviews Immunology
    Article 02 April 2024
  2. The Role of Gut-derived Short-Chain Fatty Acids in Multiple Sclerosis

    Multiple sclerosis (MS) is a chronic condition affecting the central nervous system (CNS), where the interplay of genetic and environmental factors...

    Mohamed J. Saadh, Hani Moslem Ahmed, ... Nathera Hussin Alwan in NeuroMolecular Medicine
    Article 17 April 2024
  3. Relationship Between Short-chain Fatty Acids and Parkinson’s Disease: A Review from Pathology to Clinic

    Parkinson’s disease (PD) is a complicated neurodegenerative disease, characterized by the accumulation of α-synuclein (α-syn) in Lewy bodies and...

    Wen-**ang Duan, Fen Wang, ... Chun-Feng Liu in Neuroscience Bulletin
    Article Open access 27 September 2023
  4. Changes of the Concentration of Short-Chain Fatty Acids in the Intestines of Mice with Different Types of Obesity

    We studied the production of short-chain fatty acids (SCFA) by the intestinal microbiota in mice with obesity caused by a diet and a genetic defect...

    E. V. Krolenko, O. V. Kupriyanova, ... A. V. Shestopalov in Bulletin of Experimental Biology and Medicine
    Article 01 January 2024
  5. Short-chain fatty acids in cancer pathogenesis

    Cancer is a multi-step process that can be viewed as a cellular and immunological shift away from homeostasis in response to selected infectious...

    Mark A. Feitelson, Alla Arzumanyan, ... Ira Spector in Cancer and Metastasis Reviews
    Article Open access 11 July 2023
  6. Complex regulatory effects of gut microbial short-chain fatty acids on immune tolerance and autoimmunity

    Immune tolerance deletes or suppresses autoreactive lymphocytes and is established at multiple levels during the development, activation and effector...

    Article Open access 01 March 2023
  7. Bioinformatics Approach to Identify the Pathogenetic Link of Gut Microbiota-Derived Short-Chain Fatty Acids and Ischemic Stroke

    Stroke is a life-threatening condition that impairs the arteries and causes neurological impairment. The incidence of stroke is increasing year by...

    Liang Ding, Jianing Wang, ... Pengpeng An in Molecular Neurobiology
    Article Open access 22 April 2024
  8. Association of fecal short-chain fatty acids with clinical severity and gut microbiota in essential tremor and its difference from Parkinson’s disease

    Diagnosis of essential tremor (ET) at an early stage can be difficult, especially when distinguishing it from healthy controls (HCs) and Parkinson’s...

    Pei Huang, **chen Zhang, ... Shengdi Chen in npj Parkinson's Disease
    Article Open access 17 July 2023
  9. Plasma Metabolic Analysis Reveals the Dysregulation of Short-Chain Fatty Acid Metabolism in Parkinson’s Disease

    Parkinson’s disease (PD) is a progressive neurodegenerative disorder, characterized by high morbidity, high disability rate, and slow course of...

    Ao Qi, Lulu Liu, ... Chun Cai in Molecular Neurobiology
    Article 24 January 2023
  10. Short-chain fatty acids ameliorate spinal cord injury recovery by regulating the balance of regulatory T cells and effector IL-17+ γδ T cells

    Spinal cord injury (SCI) causes motor, sensory, and autonomic dysfunctions. The gut microbiome has an important role in SCI, while short-chain fatty...

    Pan Liu, Mingfu Liu, ... Shaohui Zong in Journal of Zhejiang University-SCIENCE B
    Article 01 April 2023
  11. The Bridge Between Ischemic Stroke and Gut Microbes: Short-Chain Fatty Acids

    Short-chain fatty acids (SCFAs) are monocarboxylates produced by the gut microbiota (GM) and result from the interaction between diet and GM. An...

    Zongwei Fang, Mingrong Chen, ... **hua Zhang in Cellular and Molecular Neurobiology
    Article 28 March 2022
  12. Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation

    Barrier integrity is central to the maintenance of healthy immunological homeostasis. Impaired skin barrier function is linked with enhanced allergen...

    Aurélien Trompette, Julie Pernot, ... Benjamin J. Marsland in Mucosal Immunology
    Article Open access 07 June 2022
  13. Branched Short-Chain Fatty Acids as Biological Indicators of Microbiota Health and Links with Anthropometry

    Bacterial metabolites are one of the main mechanisms of host-microbiota interactions in the gut. Acetate, propionate, and butyrate, also known as...
    Nuria Salazar, Sonia González, ... David Rios-Covian in Biomarkers in Nutrition
    Living reference work entry 2022
  14. Branched Short-Chain Fatty Acids as Biological Indicators of Microbiota Health and Links with Anthropometry

    Bacterial metabolites are one of the main mechanisms of host-microbiota interactions in the gut. Acetate, propionate, and butyrate, also known as...
    Nuria Salazar, Sonia González, ... David Rios-Covian in Biomarkers in Nutrition
    Reference work entry 2022
  15. Sodium butyrate ameliorates diabetic retinopathy in mice via the regulation of gut microbiota and related short-chain fatty acids

    Background

    Diabetic retinopathy (DR) development is associated with disturbances in the gut microbiota and related metabolites. Butyric acid is one of...

    Yinhua Huang, Zhijie Wang, ... Shibo Tang in Journal of Translational Medicine
    Article Open access 07 July 2023
  16. Analysis of correlations between gut microbiota, stool short chain fatty acids, calprotectin and cardiometabolic risk factors in postmenopausal women with obesity: a cross-sectional study

    Background

    Microbiota and its metabolites are known to regulate host metabolism. In cross-sectional study conducted in postmenopausal women we aimed...

    Igor Łoniewski, Monika Szulińska, ... Paweł Bogdański in Journal of Translational Medicine
    Article Open access 12 December 2022
  17. Omega-6 Fatty Acids

    Omega-6 fatty acids are involved in a series of biological processes including inflammation, immune function, and carcinogenesis. Omega-6 fatty acids...
    **n Huang, Jie V. Zhao in Biomarkers in Nutrition
    Reference work entry 2022
  18. Role of Short-Chain Fatty Acids from Gut Microbiota in Neuroendocrine Pathogenesis Management

    Short-chain fatty acids (SCFAs) are important beneficial molecules produced as a result of microbial fermentation and are currently researched for...
    Neha Sahu, Prabhat Upadhyay, Sunil Kumar Mishra in Gut Microbiome in Neurological Health and Disorders
    Chapter 2022
  19. Omega-6 Fatty Acids

    Omega-6 fatty acids are involved in a series of biological processes including inflammation, immune function, and carcinogenesis. Omega-6 fatty acids...
    **n Huang, Jie V. Zhao in Biomarkers in Nutrition
    Living reference work entry 2022
  20. Short-Chain Fatty Acids Reduce Oligodendrocyte Precursor Cells Loss by Inhibiting the Activation of Astrocytes via the SGK1/IL-6 Signalling Pathway

    Short-chain fatty acids (SCFAs) are known to be actively involved in neurological diseases, but their roles in hypoxic-ischaemic brain injury (HIBI)...

    Yanmin Gao, Di **e, ... Hua Jiang in Neurochemical Research
    Article Open access 13 September 2022
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