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Serum Uric Acid and Metabolic Markers in Diabetes
Uric acid, an organic compound, is the end product of purine metabolism in the liver. Hyperuricemic conditions are implicated in the pathogenesis of...
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Serum Uric Acid and Metabolic Markers in Diabetes
Uric acid, an organic compound, is the end product of purine metabolism in the liver. Hyperuricemic conditions are implicated in the pathogenesis of...
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Eurycoma longifolia alkaloid components ameliorate hyperuricemic nephropathy via regulating serum uric acid level and relieving inflammatory reaction
Hyperuricemia is an independent risk factor for chronic kidney disease. We have previously showed the uric-acid-lowering effect of Eurycoma longifolia ...
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Serum Uric Acid Levels and Outcome of Acute Ischemic Stroke: a Dose–Response Meta-analysis
Previous meta-analyses have reported conflicting results regarding the relationship between baseline uric acid (UA) levels and acute ischemic stroke...
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Non-enzymatic Detection of Uric Acid in Serum and Urine by Fluorescent and Visual Dual-Mode Sensor Based on 3-aminophenylboric Acid Functionalized Carbon Dots
Herein, we developed a sophisticated dual-mode sensor that utilized 3-aminophenylboric acid functionalized carbon dots (APBA-CDs) to accurately...
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Co-delivery of indomethacin and uricase as a new strategy for inflammatory diseases associated with high uric acid
Uric acid is the final metabolite in humans. High level of uric acid chronically induces urate deposition, aggravates kidney damage, and...
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Serum uric acid and diabetic peripheral neuropathy: a double-edged sword
Background and objectivesResearch suggests that diabetic peripheral neuropathy (DPN) is related to high serum uric acid (SUA) level, although its...
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Increased circulating uric acid aggravates heart failure via impaired fatty acid metabolism
BackgroundIncreased circulating uric acid (UA) concentration may disrupt cardiac function in heart failure patients, but the specific mechanism...
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Metabolically healthy obesity is associated with higher risk of both hyperfiltration and mildly reduced estimated glomerular filtration rate: the role of serum uric acid in a cross-sectional study
BackgroundThe impact of metabolically healthy obesity (MHO) on kidney dysfunction remains debatable. Moreover, few studies have focused on the early...
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Exploring the causal association between uric acid and lung cancer in east Asian and European populations: a mendelian randomization study
BackgroundLung cancer still ranks first in the mortality rate of cancer. Uric acid is a product of purine metabolism in humans. Its presence in the...
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Uric Acid as a Biomarker in Nutritional Metabolism
Uric acid (UA) is a weak acid generated from the purine metabolism. UA exists in serum as urate, the salt of uric acid, and varies significantly with...
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Uric Acid as a Biomarker in Nutritional Metabolism
Uric acid (UA) is a weak acid generated from the purine metabolism. UA exists in serum as urate, the salt of uric acid, and varies significantly with...
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Serum Uric Acid as a Diagnostic Biomarker for Rheumatoid Arthritis–Associated Interstitial Lung Disease
Previous studies have suggested a correlation between uric acid (UA) and lung lesion in some diseases. However, it remains unknown whether UA...
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Evaluation of levels of uric acid and lipid profile in hospitalized patients with diabetes
ObjectiveDiabetes is the most common metabolic disorder that leads to various complications, and among these complications, disruption in the lipid...
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The relationship between uric acid and brain health from observational studies
This study conducts a systematic literature review and meta-analysis regarding the potential influence of serum uric acid levels on cerebral small...
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The serum uric acid/creatinine ratio is associated with nonalcoholic fatty liver disease in the general population
Serum uric acid-to-creatinine ratio (sUA/CrR) may be associated with metabolic syndrome components, but limited evidence exists on a relationship...
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Mutual effect of homocysteine and uric acid on arterial stiffness and cardiovascular risk in the context of predictive, preventive, and personalized medicine
BackgroundArterial stiffness is a major risk factor and effective predictor of cardiovascular diseases and a common pathway of pathological vascular...
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Uric Acid Mitigates Cognitive Deficits via TFEB-Mediated Microglial Autophagy in Mice Models of Alzheimer’s Disease
Clinical trials have demonstrated the potential neuroprotective effects of uric acid (UA) in Alzheimer’s disease (AD). However, the specific...
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Uricase sensitizes hepatocellular carcinoma cells to 5-fluorouracil through uricase-uric acid-UMP synthase axis
Conventional chemotherapy plays a key role in hepatocellular carcinoma (HCC) treatment, however, with intrinsic or acquired chemoresistance being a...
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Evaluation of the prognostic ability of serum uric acid for elderly acute coronary syndrome patients with diabetes mellitus: a prospective cohort study
Objective: This study evaluated the prognostic power of serum uric acid (UA) in predicting adverse events in elderly acute coronary syndrome (ACS)...