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Short-term zinc supplementation of zinc-deficient seniors counteracts CREMα - mediated IL-2 suppression
BackgroundAging is accompanied by a dramatic decline in the interleukin (IL)-2 production capacity of human immune cells, thus making seniors more...
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More than a meeting: identifying the needs of the community-based seniors’ services sector as providers of health promotion services
ObjectiveMany economically developed countries have seen a decline in publicly funded community programming. Within this context, community-based...
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Evidence-based medication adherence among seniors in the first year after heart failure hospitalisation and subsequent long-term outcomes: a restricted cubic spline analysis of adherence-outcome relationships
PurposeNon-adherence to heart failure (HF) medications is associated with poor outcomes. We used restricted cubic splines (RCS) to assess the...
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REview of potentially inappropriate MEDIcation pr[e]scribing in Seniors (REMEDI[e]S): French implicit and explicit criteria
PurposeTo establish a consensus on both explicit and implicit criteria in order to identify potentially inappropriate prescribing (PIP) in French...
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Dynamic Strength Index in Basketball Players: Age and Position Differences, Seasonal Variation and Association with Sprinting and Change of Direction Performance
The aim of the study was to investigate the differences in bilateral and unilateral dynamic strength index (DSI) between age categories (seniors and...
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The fusion of multi-omics profile and multimodal EEG data contributes to the personalized diagnostic strategy for neurocognitive disorders
BackgroundThe increasing prevalence of neurocognitive disorders (NCDs) in the aging population worldwide has become a significant concern due to...
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Aging, frailty, and design of built environments
Before develo** agriculture, herding or metallurgy, humans occupied most of the world. Multiple socioculturally-based responses supported their...
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NKT-like (CD3 + CD56+) cells differ from T cells in expression level of cellular protective proteins and sensitivity to stimulation in the process of ageing
BackgroundNKT-like cells are T lymphocytes coexpressing several NK cell-associated receptors. They are effector lymphocytes of innate and adaptive...
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Relative effectiveness of influenza vaccines in elderly persons in the United States, 2012/2013-2017/2018 seasons
Influenza immunization protects seniors against influenza and its potentially serious complications. It is uncertain whether standard-dose (SD)...
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Embracing Change: An International Survey Study on the Beliefs and Attitudes of Pediatric Rheumatologists Towards Biosimilars
BackgroundBiosimilars have been adopted by clinicians more slowly than anticipated in the post-marketing phase.
ObjectivesWe aimed to reveal the...
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Adult consequences of repeated nicotine and Δ9-tetrahydrocannabinol (THC) vapor inhalation in adolescent rats
RationaleUse of electronic drug delivery systems (EDDS, “e-cigarettes”) to ingest nicotine and Δ 9 -tetrahydrocannabinol (THC) has surged in...
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Intermittent not continuous hypoxia provoked haematological adaptations in healthy seniors: hypoxic pattern may hold the key
PurposeThe purpose of this single-blind, repeated measures study was to investigate the effect of two hypoxic patterns, continuous or intermittent on...
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Reverse mentoring to enhance research integrity climate
Mentors have the responsibility to guide their mentees through academic and scientific challenges that they might encounter during their educational...
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Thinking, Feeling, and Moving: Competition for Brain Resources in Health and Disease
The processProcess of thinkingThinking depends on many brainBrain regions and their interconnections. Executive functionFunction, executive (EF) is a...
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Preferred cataract surgery practices in Malaysia: a survey based study
BackgroundTo describe the preferred cataract surgery practices among Malaysian ophthalmologists and medical officers in comparison with the...
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Effects of chronic tramadol administration on cognitive flexibility in mice
RationaleTramadol is widely used for pain relief especially in seniors. However, long-term use of tramadol has serious adverse effects, including...
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Effects of a mindfulness-based versus a health self-management intervention on objective cognitive performance in older adults with subjective cognitive decline (SCD): a secondary analysis of the SCD-Well randomized controlled trial
BackgroundOlder individuals with subjective cognitive decline (SCD) perceive that their cognition has declined but do not show objective impairment...
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Lifestyle and psychosocial factors associated with maintenance of normal body mass index in college students: a cross sectional study
ObjectivesThe purpose of this study was to identify lifestyle and psychosocial factors associated with maintenance of normal body mass index (BMI,...
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Population Pharmacokinetic Model for Tramadol and O-desmethyltramadol in Older Patients
Background and ObjectivesTramadol is commonly prescribed to manage chronic pain in older patients. However, there is a gap in the literature...
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Interaction between local blood flow and tolerance to prolonged pain in the elderly
PurposeWe aimed to explore the link between local vasodilation and pain perception in elderly subjects, testing the hypothesis that altered local...
