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Host genotype, soil composition, and geo-climatic factors shape the fonio seed microbiome
BackgroundFonio ( Digitaria exilis ), an orphan millet crop, is the oldest indigenous crop in West Africa. Although the yield is low due to...
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Bassoon contributes to tau-seed propagation and neurotoxicity
Tau aggregation is a defining histopathological feature of Alzheimer’s disease and other tauopathies. However, the cellular mechanisms involved in...
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Antagonistic control of seed dormancy in rice by two bHLH transcription factors
Preharvest sprouting (PHS) due to lack of seed dormancy seriously threatens crop production worldwide. As a complex quantitative trait, breeding of...
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Dynamics of rice microbiomes reveal core vertically transmitted seed endophytes
BackgroundPlants and their associated microbiota constitute an assemblage of species known as holobionts. The plant seed microbiome plays an...
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DISE/6mer seed toxicity-a powerful anti-cancer mechanism with implications for other diseases
micro(mi)RNAs are short noncoding RNAs that through their seed sequence (pos. 2–7/8 of the guide strand) regulate cell function by targeting...
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Selection of Chemical Modifications in the siRNA Seed Region That Repress Off-Target Effect
RNA interference mediated by small interfering RNA (siRNA) has been widely used as a procedure to knock down the expression of an intended target...
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Black Seed Oil-Based Curcumin Nanoformulations Ameliorated Cuprizone-Induced Demyelination in the Mouse Hippocampus
Multiple sclerosis (MS) is a neurodegenerative disease characterized by the demyelination of nerves, axonal damage, and neuroinflammation. Cognition...
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Brain connectivity under light sedation with midazolam and ketamine during task performance and the periodic experience of pain: Examining concordance between different approaches for seed-based connectivity analysis
This work focused on functional connectivity changes under midazolam and ketamine sedation during performance of a memory task, with the periodic...
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Iodine-125 seed represses the growth and facilitates the apoptosis of colorectal cancer cells by suppressing the methylation of miR-615 promoter
BackgroundColorectal cancer (CRC) represents a common malignancy in gastrointestinal tract. Iodine-125 ( 125 I) seed implantation is an emerging...
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Trait related aberrant connectivity in clinically stable patients with schizophrenia: A seed based resting state fMRI study
Aberrant resting-state connectivity within and between the Default Mode Network, the Executive Control Network, and the Salience Network is...
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Tau seed amplification assay reveals relationship between seeding and pathological forms of tau in Alzheimer’s disease brain
Tau seed amplification assays (SAAs) directly measure the seeding activity of tau and would therefore be ideal biomarkers for clinical trials...
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Fine-map** of a putative glutathione S-transferase (GST) gene responsible for yellow seed colour in flax (Linum usitatissimum)
ObjectiveThe brown seed coat colour of flax ( Linum ustiatissimum ) results from proanthocyanidin synthesis and accumulation. Glutathione...
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Cerebrospinal fluid lipoproteins inhibit α-synuclein aggregation by interacting with oligomeric species in seed amplification assays
BackgroundAggregation of α-synuclein (α-syn) is a prominent feature of Parkinson’s disease (PD) and other synucleinopathies. Currently, α-syn seed...
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Grape seed extract protects rat offspring hippocampus from the silicon dioxide nanoparticles’ neurotoxicity
Silicon dioxide nanoparticles (SiO 2 -NPs) can be found in many products, such as composites, paints, ceramics, consumer products, and food additives....
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Seed transmission of raspberry bushy dwarf virus is blocked in Nicotiana benthamiana plants by preventing virus entry into the embryo from the infected embryo sac and endosperm
Raspberry bushy dwarf virus (RBDV) is transmitted through seed in infected red raspberry plants after pollination with pollen grains from healthy red...
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Combining skin and olfactory α-synuclein seed amplification assays (SAA)—towards biomarker-driven phenoty** in synucleinopathies
Seed amplification assays (SAA) are becoming commonly used in synucleinopathies to detect α-synuclein aggregates. Studies in Parkinson’s disease (PD)...
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A new conditional region growing approach for microcalcification delineation in mammograms
Microcalcifications (MCs) are considered as the first indicator of breast cancer development. Their morphology, in terms of shape and size, is...
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Ameliorative effects of Guilandina bonduc L. aqueous seed extract on letrozole induced polycystic ovary syndrome in female wistar albino rats
The current study aims to identify the phytochemical constituents of Guilandina bonduc L. aqueous seed extract to evaluate their antioxidant...
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Corylus jacquemontii Decne.: a promising lesser-known multipurpose tree species of the Himalayan region
The article presents an overview of Indian hazelnut ( Corylus jacquemontii )- a multipurpose threatened species of the Himalayan region of high...
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Role of DOG1 and FT, Key Regulators of Seed Dormancy, in Adaptation of Arabidopsis thaliana from the Northern Natural Populations
AbstractThe results of assessing the primary dormancy, greatly important for adaptation, of seeds of A. thaliana plants from northern natural...
