Search
Search Results
-
Genetic profiles of Schistosoma haematobium parasites from Malian transmission hotspot areas
BackgroundAlthough schistosomiasis is a public health issue in Mali, little is known about the parasite genetic profile. The purpose of this study...
-
A duplex tetra-primer ARMS-PCR assay to discriminate three species of the Schistosoma haematobium group: Schistosoma curassoni, S. bovis, S. haematobium and their hybrids
BackgroundThe use of applications involving single nucleotide polymorphisms (SNPs) has greatly increased since the beginning of the 2000s, with the...
-
Efficacy and safety of single-dose artesunate plus sulfalene/pyrimethamine combined with praziquantel for the treatment of children with Schistosoma mansoni or Schistosoma haematobium in western Kenya: a randomised, open-label controlled trial
BackgroundReliance on praziquantel for the treatment and control of schistosomiasis is likely to facilitate the emergence of drug resistance....
-
Severity of Schistosoma haematobium co-infection with malaria in school-children is potentially modulated by host CD14 gene variants
ObjectiveSchistosomiasis remains a chronic disease of global importance, especially in many rural areas of the world where co-infection with Plasmodiu...
-
Immunochromatography Lateral Flow Strip Enhancement Based on Passive Gold Nanoparticles Conjugation to Detect Schistosma haematobium Antigens in Human Serum
PurposeThis study aimed to develop and evaluate a lateral flow card for the detection of active Schistosoma haematobium infection.
Methods ...
-
Fine-scale-map** of Schistosoma haematobium infections at the school and community levels and intermediate host snail abundance in the north of Pemba Island: baseline cross-sectional survey findings before the onset of a 3-year intervention study
BackgroundSchistosomiasis elimination has gained renewed priority in the WHO guidance documents published in 2020 and 2022. The SchistoBreak project,...
-
Impact of Schistosoma sp., Infection on Biological, Feeding, Physiological, Histological, and Genotoxicological Aspects of Biomphalaria alexandrina and Bulinus truncatus Snails
BackgroundTrematode infections of the genus Schistosoma can induce physiological and behavioral changes in intermediate snail hosts. This is because...
-
Mastomys natalensis (Smith, 1834) as a natural host for Schistosoma haematobium (Bilharz, 1852) Weinland, 1858 x Schistosoma bovis Sonsino, 1876 introgressive hybrids
Cercarial emission of schistosomes is a determinant in the transmission to the definitive host and constitutes a good marker to identify which...
-
Characterizing genetic variation on the Z chromosome in Schistosoma japonicum reveals host-parasite co-evolution
BackgroundSchistosomiasis is a neglected tropical disease that afflicts millions of people worldwide; it is caused by Schistosoma, the only dioecious...
-
Molecular insights into the heat shock proteins of the human parasitic blood fluke Schistosoma mansoni
BackgroundHeat shock proteins (HSPs) are evolutionarily conserved proteins, produced by cells in response to hostile environmental conditions, that...
-
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for differential identification of adult Schistosoma worms
BackgroundSchistosomiasis is a major neglected tropical disease that affects up to 250 million individuals worldwide. The diagnosis of human...
-
Schistosoma haematobium (Bladder Fluke): Life Cycle and Morphology
This species belongs to the unique group of trematodes, where male and females live as adults lifelong (up to 20 years) closely united together,...
-
R-praziquantel integrated population pharmacokinetics in preschool- and school-aged African children infected with Schistosoma mansoni and S. haematobium and Lao adults infected with Opisthorchis viverrini
Racemic praziquantel (PZQ) is the standard treatment for schistosomiasis and liver fluke infections (opisthorchiasis and clonorchiasis). The...
-
IPSE, an abundant egg-secreted protein of the carcinogenic helminth Schistosoma haematobium, promotes proliferation of bladder cancer cells and angiogenesis
BackgroundSchistosoma haematobium, the helminth causing urogenital schistosomiasis, is a known bladder carcinogen. Despite the causal link between S....
-
Schistosoma japonicum Associated Colorectal Cancer and Its Management
BackgroundAn association between Schistosoma japonicum and colorectal cancer in humans has been known since a long time; however, this association...
-
Co-infection of Plasmodium falciparum and Schistosoma mansoni is associated with anaemia
BackgroundMalaria and schistosomiasis persist as major public health challenge in sub-Saharan Africa. These infections have independently and also in...
-
An accident waiting to happen? Exposing the potential of urogenital schistosomiasis transmission in the Lake Albert region, Uganda
BackgroundUrogenital schistosomiasis caused by the parasitic blood fluke Schistosoma haematobium is the most common form of that constitutes a...
-
Schistosoma japonicum EKLF/KLF1 is a potential immune target to tackle schistosomiasis
BackgroundInterruption of parasite reproduction by targeting migrating schistosomula is a promising strategy for managing schistosomiasis. Hepatic...
-
The impact of mass drug administration on Schistosoma haematobium infection: what is required to achieve morbidity control and elimination?
BackgroundSchistosomiasis remains an endemic parasitic disease causing much morbidity and, in some cases, mortality. The World Health Organization...
-
Exploring the immune interactions between Oncomelania hupensis and Schistosoma japonicum, with a cross-comparison of immunological research progress in other intermediate host snails
Schistosomiasis, the second largest parasitic disease in the world after malaria, poses a significant threat to human health and causes public health...
