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Scale-Free Dynamics in Instantaneous Alpha Frequency Fluctuations: Validation, Test–Retest Reliability and Its Relationship with Task Manipulations
Previous studies showed that scale-free structures and long-range temporal correlations are ubiquitous in physiological signals (e.g.,...
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Scale free avalanches in excitatory-inhibitory populations of spiking neurons with conductance based synaptic currents
We investigate spontaneous critical dynamics of excitatory and inhibitory (EI) sparsely connected populations of spiking leaky integrate-and-fire...
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Large-Scale Nanogrooved Photonic Crystals for Label-Free Biosensing by Guided-Mode Resonance
We have developed large-scale one-dimensional photonic crystals from standard recordable Blu-ray disks, tailored to sense unlabeled biorecognition... -
Large-scale reference-free analysis of flavivirus sequences in Aedes aegypti whole genome DNA sequencing data
Flaviviruses are a diverse group of RNA viruses, which include the etiological agents of Zika, dengue and yellow fever that are transmitted by...
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Abnormal large-scale resting-state functional networks in drug-free major depressive disorder
Major depressive disorder (MDD) is associated with aberrant function and interaction encompassing large parts of cortical, subcortical and limbic...
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Self-organizing scale-free patterns in a phase-modulated periodic connecting system
ObjectiveThe regularity of scale-free patterns in rank-size relations has been observed in word frequency, city size distribution, firm size...
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Cluster burst synchronization in a scale-free network of inhibitory bursting neurons
We consider a scale-free network of inhibitory Hindmarsh–Rose (HR) bursting neurons, and make a computational study on coupling-induced cluster burst...
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A miniaturized mesoscope for the large-scale single-neuron-resolved imaging of neuronal activity in freely behaving mice
Exploring the relationship between neuronal dynamics and ethologically relevant behaviour involves recording neuronal-population activity using...
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An injectable, nanostructured implant for the delivery of adenosine triphosphate: towards long-acting formulations of small, hydrophilic drugs
While long-acting injectable treatments are gaining increasing interest in managing chronic diseases, the available drug delivery systems almost...
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CRAG: de novo characterization of cell-free DNA fragmentation hotspots in plasma whole-genome sequencing
The fine-scale cell-free DNA fragmentation patterns in early-stage cancers are poorly understood. We developed a de novo approach to characterize the...
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Predicting the risk of malaria re-introduction in countries certified malaria-free: a systematic review
BackgroundPredicting the risk of malaria in countries certified malaria-free is crucial for the prevention of re-introduction. This review aimed to...
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Wharton’s jelly mesenchymal stem cells transplantation for critical limb ischemia in patients with type 2 diabetes mellitus: a preliminary report of phase I clinical trial
Peripheral artery disease (PAD) affects more than 230 million people worldwide, with approximately 11% of patients presenting with advanced-stage PAD...
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Fractal Similarity of Pain Brain Networks
The conscious perception of pain is the result of dynamic interactions of neural activities from local brain regions to distributed brain networks.... -
Efficacy and safety of needle-free jet injector-assisted intralesional treatments in dermatology—a systematic review
Needle-free jet injectors are used for the intralesional treatment of various dermatological indications. However, a systematic review that evaluates...
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Multiscale Label-Free Imaging of Fibrillar Collagen in the Tumor Microenvironment
With recent advances in cancer therapeutics, there is a great need for improved imaging methods for characterizing cancer onset and progression in a... -
Nomogram for Predicting Long-term Outcomes of Encephaloduroarteriosynangiosis in Toddlers with Moyamoya Disease: a Longitudinal and Cross-sectional Study
We investigated the long-term outcomes of encephaloduroarteriosynangiosis (EDAS) for stroke prevention in toddlers with moyamoya disease (MMD) using...
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Out of Sequence: Genome-Scale Testing
After a brief discussion of the evolution of whole genome analysis in diagnostic genetic laboratories (encompassing chromosome analysis, microarrays... -
Scale-free behaviour and metastable brain-state switching driven by human cognition, an empirical approach
We developed a framework to study brain dynamics under cognition. In particular, we investigated the spatiotemporal properties of brain state...
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Cancer signature ensemble integrating cfDNA methylation, copy number, and fragmentation facilitates multi-cancer early detection
Cell-free DNA (cfDNA) sequencing has demonstrated great potential for early cancer detection. However, most large-scale studies have focused only on...
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Efficacy of curcumin for amelioration of radiotherapy-induced oral mucositis: a preliminary randomized controlled clinical trial
BackgroundOral mucositis (OM) is one of the main problems in almost all patients undergoing head and neck radiotherapy (RT). Owning to the...