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Randomized phase II trial of MRI-guided salvage radiotherapy for prostate cancer in 4 weeks versus 2 weeks (SHORTER)
BackgroundUltra-hypofractionated image-guided stereotactic body radiotherapy (SBRT) is increasingly used for definitive treatment of localized...
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Salvage radiotherapy strategy and its prognostic significance for patients with locoregional recurrent cervical cancer after radical hysterectomy: a multicenter retrospective 10-year analysis
ObjectiveWe aimed to evaluate the clinical efficacy and prognostic significance of intensity-modulated radiotherapy (IMRT)-based salvage concurrent...
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Safety and efficacy of CT-guided radioactive iodine-125 seed implantation as a salvage treatment for recurrent head and neck cancer after two or more courses of radiotherapy
BackgroundIn the past, patients with recurrent head and neck cancer (rHNC) who had previously received a high dose of radiation and were unable to...
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Impact of persistent PSA after salvage radical prostatectomy: a multicenter study
Background and objectivePersistent prostatic specific antigen (PSA) represents a poor prognostic factor for recurrence after radical prostatectomy...
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Radiotherapy for Meningioma
Meningiomas are the most common primary intracranial brain tumor, and have a heterogeneous biology and an unmet need for targeted treatment options....
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Management after initial surgery of nonfunctioning pituitary adenoma: surveillance, radiotherapy or surgery?
IntroductionThe first line of treatment for nonfunctioning pituitary adenoma (NFPA) is surgery. Adjuvant radiotherapy or surveillance and new...
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Phase III randomised controlled trial on PSMA PET/CT guided hypofractionated salvage prostate bed radiotherapy of biochemical failure after radical prostatectomy for prostate cancer (PERYTON-trial): study protocol
BackgroundSalvage external beam radiotherapy (sEBRT) for patients with a biochemical recurrence (BCR) after radical prostatectomy provides a 5-year...
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Comparison of hypofractionation and standard fractionation for post-prostatectomy salvage radiotherapy in patients with persistent PSA: single institution experience
BackgroundHypofractionated post-prostatectomy radiotherapy is emerging practice, however with no randomized evidence so far to support it’s use....
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Stereotactic Radiotherapy in the Treatment of Prostate Cancer
Stereotactic body radiotherapy (SBRT) is a technologically sophisticated form of radiotherapy and well-established treatment option for patients with...
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Introduction of salvage prostatectomy in Denmark: the initial experience
ObjectiveTo introduce salvage prostatectomy in Denmark. Prior to this, no national curative treatment for recurrent prostate cancer following...
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Survival outcomes including salvage therapy of adult head and neck para-meningeal rhabdomyosarcoma: a multicenter retrospective study from Japan
BackgroundRhabdomyosarcoma is the most common soft tissue sarcoma in children, but rare in adults. Para-meningeal rhabdomyosarcoma in head and neck...
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Toxicity When Combining Immunotherapy and Radiotherapy
Background: Radiation toxicity in monotherapy has been widely studied, together with its possible combinations with...
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Current radiotherapy for recurrent head and neck cancer in the modern era: a state-of-the-art review
BackgroundIn the management of head and neck cancer (HNC) patients, local recurrence is a common cause of treatment failure. Only a few patients with...
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Clinical and dosimetric outcomes of image-guided, dose-painted radiotherapy in muscle invasive bladder cancer
Purpose/ObjectiveDefinitive radiotherapy (RT) is an alternative to radical cystectomy for select patients with muscle invasive bladder cancer (MIBC);...
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Prostate Cancer and Radiotherapy
Prostate cancer represents the most common malignancy in males [1, 2] and its incidence increased in the last decades due to the introduction of the...
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Immediate radiotherapy versus observation in patients with node-positive prostate cancer after radical prostatectomy
BackgroundThe optimal management of node-positive (pN1) prostate cancer following radical prostatectomy (RP) remains uncertain. Despite randomized...
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Dosimetric and clinical analysis of pseudo-progression versus recurrence after hypo-fractionated radiotherapy for brain metastases
BackgroundThe main challenge in follow-up duration of patients with brain metastases after stereotactic radiotherapy is to distinguish between...
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Is radiotherapy after radical prostatectomy associated with higher other-cause mortality?
PurposeThe aim of this study was to reveal the association between the other-cause mortality (OCM) and post-radical prostatectomy (RP) salvage...
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Spine Radiotherapy
A large portion of cancer patients will develop spinal metastases during the natural course of their disease. While spine metastases may be...
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Efficacy of salvage surgery versus re-irradiation for isolated regional lymph node recurrence in patients with nasopharyngeal carcinoma
BackgroundTo compare the clinical characteristics and prognoses of patients with isolated regional lymph node recurrent nasopharyngeal carcinoma...
