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Nose-down saddle tilt improves gross efficiency during seated-uphill cycling
Riding uphill presents a challenge to competitive and recreational cyclists. Based on only limited evidence, some scientists have reported that...
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Saddle-Reset for Robust Parameter Estimation and Identifiability Analysis of Nonlinear Mixed Effects Models
Parameter estimation of a nonlinear model based on maximizing the likelihood using gradient-based numerical optimization methods can often fail due...
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Scale free avalanches in excitatory-inhibitory populations of spiking neurons with conductance based synaptic currents
We investigate spontaneous critical dynamics of excitatory and inhibitory (EI) sparsely connected populations of spiking leaky integrate-and-fire...
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Physical Fitness of Thoroughbred Horse Racing Jockeys
PurposeThoroughbred racing jockeys compete at maximum physiological capacity in a sport with a high risk of falls and injury. A greater understanding...
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Single-compartment model of a pyramidal neuron, fitted to recordings with current and conductance injection
For single neuron models, reproducing characteristics of neuronal activity such as the firing rate, amplitude of spikes, and threshold potentials as...
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Geometric characterization of dynamical structure for neural firing activities induced by inhibitory pulse
In general, inhibitory stimuli are thought to inhibit neuronal firing, but they may actually enhance firing sometimes, such as post-inhibitory...
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Extreme multistability and phase synchronization in a heterogeneous bi-neuron Rulkov network with memristive electromagnetic induction
Memristive electromagnetic induction effect has been widely explored in bi-neuron network with homogeneous neurons, but rarely in bi-neuron network...
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Nonlinear mechanism for the enhanced bursting activities induced by fast inhibitory autapse and reduced activities by fast excitatory autapse
The paradoxical phenomena that excitatory modulation does not enhance but reduces or inhibitory modulation not suppresses but promotes neural firing...
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Morphological and Dynamic Analysis of the Right Atrioventricular Junction in Healthy Subjects with 4D Computed Tomography
PurposeTo improve knowledge of the tricuspid valve and right atrioventricular junction (RAVJ) coupling, four-dimensional (4D) imaging is mandatory...
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A unified physiological framework of transitions between seizures, sustained ictal activity and depolarization block at the single neuron level
The majority of seizures recorded in humans and experimental animal models can be described by a generic phenomenological mathematical model, the...
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Methodology to Analyse Three-Dimensional Asymmetries in the Forces Applied to the Pedals in Cycling
The asymmetries study between both legs of the forces applied to the pedals in cycling is important because they may affect the performance of the...
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Optimization of ictal aborting stimulation using the dynamotype taxonomy
Electrical stimulation is an increasingly popular method to terminate epileptic seizures, yet it is not always successful. A potential reason for...
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Network mechanism for insect olfaction
Early olfactory pathway responses to the presentation of an odor exhibit remarkably similar dynamical behavior across phyla from insects to mammals,...
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Slow negative feedback enhances robustness of square-wave bursting
Square-wave bursting is an activity pattern common to a variety of neuronal and endocrine cell models that has been linked to central pattern...
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Multistability in neural systems with random cross-connections
Neural circuits with multiple discrete attractor states could support a variety of cognitive tasks according to both empirical data and model...
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Entire Mitral Valve Reconstruction Using Porcine Extracellular Matrix: Adding a Ring Annuloplasty
PurposeThis study investigated the implications of inserting a flexible annuloplasty ring after reconstructing the entire mitral valve in a porcine...
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The neuronal and synaptic dynamics underlying post-inhibitory rebound burst related to major depressive disorder in the lateral habenula neuron model
A burst behavior observed in the lateral habenula (LHb) neuron related to major depressive disorder has attracted much attention. The burst is...
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A novel memristive neuron model and its energy characteristics
The functional neurons are basic building blocks of the nervous system and are responsible for transmitting information between different parts of...
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Codimension-2 parameter space structure of continuous-time recurrent neural networks
If we are ever to move beyond the study of isolated special cases in theoretical neuroscience, we need to develop more general theories of neural...