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The hibernation-derived compound SUL-138 shifts the mitochondrial proteome towards fatty acid metabolism and prevents cognitive decline and amyloid plaque formation in an Alzheimer’s disease mouse model
BackgroundAlzheimer’s disease (AD) is the most prevalent neurodegenerative disease worldwide and remains without effective cure. Increasing evidence...
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FDG-PET/CT-based respiration-gated lung segmentation and quantification of lung inflammation in COPD patients
Objective and results descriptionThe study objective was to investigate the potential of quantitative measures of pulmonary inflammation by...
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Molecular detection of piroplasmids in mammals from the Superorder Xenarthra in Brazil
Xenarthra mammals can be found from southern North America to southern South America, including all Brazilian biomes. Although it has been shown that...
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Vector role and human biting activity of Anophelinae mosquitoes in different landscapes in the Brazilian Amazon
BackgroundEnvironmental disturbance, deforestation and socioeconomic factors all affect malaria incidence in tropical and subtropical endemic areas....
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Genetic diversity of Toxoplasma gondii in South America: occurrence, immunity, and fate of infection
Toxoplasma gondii is an intracellular parasite with a worldwide distribution. Toxoplasma gondii infections are of great concern for public health,...
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Colonization of patients hospitalized at orthopedic department of tertiary hospital in Uganda with extended-spectrum beta-lactamase-producing enterobacterales
BackgroundBeta-lactamase production remains the most contributing factor to beta-lactam resistance. Extended-Spectrum Beta-Lactamase-Producing...
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Effect of ultraviolet LED and trap height on catches of host-seeking anopheline mosquitoes by using a low-cost passive light trap in northeast Brazil
Light traps have been widely used for monitoring malaria vectors, although drawbacks remain. In this context, new tools and attractants are always...
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Monthly biological larviciding associated with a tenfold decrease in larval density in fish farming ponds and reduced community-wide malaria incidence in northwestern Brazil
BackgroundLarvicides are typically applied to fixed and findable mosquito breeding sites, such as fish farming ponds used in commercial aquaculture,...
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Genome-wide interrogation of structural variation reveals novel African-specific prostate cancer oncogenic drivers
BackgroundAfrican ancestry is a significant risk factor for advanced prostate cancer (PCa). Mortality rates in sub-Saharan Africa are 2.5-fold...
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Pseudotyped Viruses for Marburgvirus and Ebolavirus
Marburg virus (MARV) and Ebola virus (EBOV) of the Filoviridae family are the most lethal viruses in terms of mortality rate. However, the...
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Phytochemistry and biological activity of Erigeron annuus (L.) Pers
Erigeron annuus L. is a flowering herb of North America, Europe, Asia and Russia. This plant is used as folk medicine in China for the cure of...
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Seroprevalence and isolation of Toxoplasma gondii in sheep intended for human consumption in Paraíba, northeastern Brazil
Toxoplasma gondii is a zoonotic parasite capable of infecting almost all warm-blooded animals. Currently, studies assessing the viability of cysts...
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Metagenomic prediction of antimicrobial resistance in critically ill patients with lower respiratory tract infections
BackgroundAntimicrobial resistance (AMR) is rising at an alarming rate and complicating the management of infectious diseases including lower...
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Assessment of the susceptibility status of Aedes aegypti (Diptera: Culicidae) populations to pyriproxyfen and malathion in a nation-wide monitoring of insecticide resistance performed in Brazil from 2017 to 2018
BackgroundChemical mosquito control using malathion has been applied in Brazil since 1985. To obtain chemical control effectiveness, vector...
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Malaria Test, Treat and Track policy implementation in Angola: a retrospective study to assess the progress achieved after 4 years of programme implementation
BackgroundMalaria is one of the main causes of death in Angola, particularly among children under 5 years of age. An essential means to improve the...
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Distribution modeling of Amblyomma rotundatum and Amblyomma dissimile in Brazil: estimates of environmental suitability
The number of reports of tick parasitism in amphibians and reptiles has increased over the past few years, including new host and location records...
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A genomic variation map provides insights into peanut diversity in China and associations with 28 agronomic traits
Peanut ( Arachis hypogaea L.) is an important allotetraploid oil and food legume crop. China is one of the world’s largest peanut producers and...
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Lung Cancer
Lung cancer has a complex pathophysiology and is one of the leading causes of death all over the world. Cutting edge imaging modalities and omics...
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Polystome Species of the Australian Lungfish, Chelonians and the Common Hippopotamus
This chapter brings together all known polystomes of fish, i.e. the Australian lungfish, chelonians and mammal, i.e. the common hippopotamus, namely...
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Variation of dipteran ectoparasites (Streblidae) on Anoura geoffroyi Gray, 1838 (Phyllostomidae) in two caves in southeastern Brazil
Bats are parasitized by many different arthropods, among which the dipteran families Nycteribiidae and Streblidae are exclusive to bats. Researches...
