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miR-491-3p is Downregulated in Retinoblastoma and Inhibit Tumor Cells Growth and Metastasis by Targeting SNN
Retinoblastoma (Rb) is the most common pediatric malignant tumor of the eyes. Previous studies demonstrated that miR-491-3p is downregulated in...
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Predicting the temporal-dynamic trajectories of cortical neuronal responses in non-human primates based on deep spiking neural network
Deep convolutional neural networks (CNNs) are commonly used as computational models for the primate ventral stream, while deep spiking neural...
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Brain-guided manifold transferring to improve the performance of spiking neural networks in image classification
Spiking neural networks (SNNs), as the third generation of neural networks, are based on biological models of human brain neurons. In this work, a...
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Efficient multi-scale representation of visual objects using a biologically plausible spike-latency code and winner-take-all inhibition
Deep neural networks have surpassed human performance in key visual challenges such as object recognition, but require a large amount of energy,...
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Phylogenetic and network analysis of Pediculus humanus in Nigeria reveal the presences of clade E body lice and novel haplotypes
An investigation was conducted for the first time to determine the prevalence and genetic diversity of human lice, for the first time in Nigeria,...
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Mass spectrometric profiling of tryptic digests of trifluoroethanol extracts from core needle biopsies of breast cancer tissues is a viable sample screening tool for biomarker discovery
Application of classifying limited sampling biopsies by matrix-assisted laser desorption/ionization time-of-flight (MALDI-ToF) based mass spectral...
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Memristive leaky integrate-and-fire neuron and learnable straight-through estimator in spiking neural networks
Compared to artificial neural networks (ANNs), spiking neural networks (SNNs) present a more biologically plausible model of neural system dynamics....
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A spatiotemporal energy model based on spiking neurons for human motion perception
Inspired by the motion processing pathway, this paper proposes a bio-inspired feedforward spiking network model based on Hodgkin–Huxley neurons for...
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Learning heterogeneous delays in a layer of spiking neurons for fast motion detection
The precise timing of spikes emitted by neurons plays a crucial role in sha** the response of efferent biological neurons. This temporal dimension...
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Quantifying harmony between direct and indirect pathways in the basal ganglia: healthy and Parkinsonian states
The basal ganglia (BG) show a variety of functions for motor and cognition. There are two competitive pathways in the BG; direct pathway (DP) which...
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Break-up and recovery of harmony between direct and indirect pathways in the basal ganglia: Huntington’s disease and treatment
The basal ganglia (BG) in the brain exhibit diverse functions for motor, cognition, and emotion. Such BG functions could be made via competitive...
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Characterization of HIV variants from paired Cerebrospinal fluid and Plasma samples in primary microglia and CD4+ T-cells
Despite antiretroviral therapy (ART), HIV persistence in the central nervous system (CNS) continues to cause a range of cognitive impairments in...
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Integrative Analysis of MicroRNAs and mRNAs in LPS-Induced Macrophage Inflammation Based on Adipose Tissue Stem Cell Therapy
Severe inflammation can lead to multiple organ dysfunction syndrome, which has high mortality. Adipose-derived stem cells have been shown to affect...
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Molecular evidence for a new lineage within the Acanthamoeba T4 genotype
Acanthamoeba is a widespread free-living amoeba capable of causing serious infections in humans and other animals, such as amoebic keratitis,...
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Cellular heterogeneity in red and melanized focal muscle changes in farmed Atlantic salmon (Salmo salar) visualized by spatial transcriptomics
Spatial transcriptomics is a technique that provides insight into gene expression profiles in tissue sections while retaining structural information....
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Stakes of neuromorphic foveation: a promising future for embedded event cameras
Foveation can be defined as the organic action of directing the gaze towards a visual region of interest to acquire relevant information selectively....
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Automatic Diagnosis of Mild Cognitive Impairment Using Siamese Neural Networks
The use of Artificial Intelligence techniques as an aid tool in the medical field is a current and undeniable challenge. In this context, similarity...
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Phylogenetic and diversity analyses revealed that leek yellow stripe virus population consists of three types: S, L, and N
Phylogenetic and evolutionary analyses were performed on the P1 and CP genes of global isolates to clarify the phylogrou** of leek yellow stripe...
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Mesenchymal–epithelial transition in lymph node metastases of oral squamous cell carcinoma is accompanied by ZEB1 expression
BackgroundOral squamous cell carcinoma (OSCC), an HPV-negative head and neck cancer, frequently metastasizes to the regional lymph nodes but only...
