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  1. SIRT1 activation promotes energy homeostasis and reprograms liver cancer metabolism

    Background

    Cancer cells are characterized by uncontrolled cell proliferation and impaired bioenergetics. Sirtuins are a family of highly conserved...

    Benluvankar Varghese, Ugo Chianese, ... Angela Nebbioso in Journal of Translational Medicine
    Article Open access 15 September 2023

  2. Targeting Mitochondria as a Strategy to Inhibit Cellular Senescence

    Purpose of Review

    Cellular senescence is implicated in aging and age-related diseases. Because mitochondrial stress is one of the triggers of cellular...

    Irene L. Tan, Michael C. Velarde in Current Molecular Biology Reports
    Article 24 February 2021
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