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  1. Reference Materials for Improving Reliability of Multiomics Profiling

    High-throughput technologies for multiomics or molecular phenomics profiling have been extensively adopted in biomedical research and clinical...

    Luyao Ren, Leming Shi, Yuanting Zheng in Phenomics
    Article Open access 06 March 2024
  2. Development of preimplantation genetic testing for monogenic reference materials using next-generation sequencing

    Objective

    Preimplantation genetic testing for monogenic disorders (PGT-M) has been used for over 20 years to detect many serious genetic conditions....

    Weihua Zhao, Yanyan Song, ... Shoufang Qu in BMC Medical Genomics
    Article Open access 23 January 2024
  3. EU surveys insights: analytical tools, future directions, and the essential requirement for reference materials in wastewater monitoring of SARS-CoV-2, antimicrobial resistance and beyond

    Background

    Wastewater surveillance (WWS) acts as a vigilant sentinel system for communities, analysing sewage to protect public health by detecting...

    Valentina Paracchini, Mauro Petrillo, ... Antonio Marchini in Human Genomics
    Article Open access 27 June 2024
  4. Referencing: Use of Reference Manager

    Referencing in research is a critical aspect of academic writing. It involves citing the sources of information and ideas we have used in the...
    Chapter 2023
  5. Reference Standards to Support Quality of Synthetic Peptide Therapeutics

    Purpose

    Peptides are an important class of therapeutics. Their quality is evaluated using a series of analytical tests, many of which depend on...

    Diane McCarthy, Ying Han, ... Fouad Atouf in Pharmaceutical Research
    Article Open access 22 March 2023
  6. The reference range of lamotrigine in the treatment of epilepsy in children: a systematic review

    Purpose

    This study intends to assess the reference range of lamotrigine concentration for treating childhood epilepsy.

    Methods

    PubMed, Ovid-Embase,...

    **g**g Chen, Liang Huang, ... Lingli Zhang in European Journal of Clinical Pharmacology
    Article Open access 31 October 2023
  7. Reference-free inferring of transcriptomic events in cancer cells on single-cell data

    Background

    Cancerous cells’ identity is determined via a mixture of multiple factors such as genomic variations, epigenetics, and the regulatory...

    Batuhan Eralp, Emre Sefer in BMC Cancer
    Article Open access 20 May 2024
  8. Reference Gene Validation in the Embryonic and Postnatal Brain in the Rat Hyperhomocysteinemia Model

    Maternal hyperhomocysteinemia (HCY) induced by genetic defects in methionine cycle enzymes or vitamin imbalance is known to be a pathologic factor...

    Anna A. Kovalenko, Alexander P. Schwarz, ... Alexander V. Arutjunyan in Neurotoxicity Research
    Article 29 February 2024
  9. Food Contact Materials

    Food contact materials (FCM) are all materials and articles intended to come into direct or indirect contact with food. The definition of food...
    Haixia Sui in Nutritional Toxicology
    Chapter 2022
  10. Full-Length Characterization of Novel HLA-DRB1 Alleles for Reference Database Submission

    The prerequisite for successful HLA genoty** is the integrity of the large allele reference database IPD-IMGT/HLA. Consequently, it is in the...
    Kathrin Putke, Viviane Albrecht, ... Anja Klussmeier in HLA Ty**
    Protocol 2024
  11. Retrograde amnesia abolishes the self-reference effect in anterograde memory

    Is retrograde amnesia associated with an ability to know who we are and imagine what we will be like in the future? To answer this question, we had...

    Debora Stendardi, Flavia De Luca, ... Elisa Ciaramelli in Experimental Brain Research
    Article Open access 14 July 2023
  12. A Reference Standard for Analytical Testing of Erythropoietin

    Purpose

    Erythropoietin (EPO) is a 165 amino acid protein that promotes the proliferation of erythrocytic progenitors. A decrease in endogenous EPO...

    Hui** Tu, Kevin Carrick, ... Fouad Atouf in Pharmaceutical Research
    Article Open access 15 March 2022
  13. Reference intervals for plasma amyloid-β, total tau, and phosphorylated tau181 in healthy elderly Chinese individuals without cognitive impairment

    Background

    Plasma amyloid-β (Aβ) peptides and tau proteins are promising biomarkers of Alzheimer’s disease (AD), not only for predicting Aβ and tau...

    **gshan Chen, Xue Zhao, ... Fu-Dong Shi in Alzheimer's Research & Therapy
    Article Open access 26 May 2023
  14. Reference genome assemblies reveal the origin and evolution of allohexaploid oat

    Common oat ( Avena sativa ) is an important cereal crop serving as a valuable source of forage and human food. Although reference genomes of many...

    Yuanying Peng, Honghai Yan, ... Changzhong Ren in Nature Genetics
    Article Open access 18 July 2022
  15. Calibration of a serum reference standard for Group B streptococcal polysaccharide conjugate vaccine development using surface plasmon resonance

    Group B streptococcus (GBS) is a leading cause of neonatal morbidity and mortality worldwide. Development of a maternal vaccine to protect newborns...

    Alexandre Esadze, Christopher D. Grube, ... Raphael Simon in npj Vaccines
    Article Open access 19 May 2023
  16. Demonstration of Physicochemical and Functional Similarity of the Biosimilar BAT1806/BIIB800 to Reference Tocilizumab

    Background and Objective

    Tocilizumab is an immunoglobulin G1 monoclonal antibody targeting the interleukin-6 receptor (IL-6R). BAT1806/BIIB800...

    Yujie Liu, Jianhua **e, ... Cuihua Liu in BioDrugs
    Article Open access 18 June 2024
  17. Population pharmacokinetic, pharmacodynamic and efficacy modeling of SB12 (proposed eculizumab biosimilar) and reference eculizumab

    Purpose

    To describe, compare similarity of pharmacokinetic (PK), pharmacodynamic (PD) and efficacy of SB12 and reference eculizumab (ECU) and find...

    Hyuna Lee, Jihye Park, ... Jungryul Kim in European Journal of Clinical Pharmacology
    Article Open access 30 May 2024
  18. Patterns in the Public Square: Reference Models for Regulatory Science

    Science and engineering involve discovery, representation, explanation, and exploitation of recurrent patterns, observed as phenomena. Model-based...

    William D. Schindel in Annals of Biomedical Engineering
    Article 07 October 2022
  19. Reference values for estimated VO2max by two submaximal cycle tests: the Åstrand-test and the Ekblom-Bak test

    Aims

    Submaximal tests estimating VO 2 max have inherent biases; hence, using VO 2 max estimations from the same test is essential for reducing this...

    Daniel Väisänen, Björn Ekblom, ... Elin Ekblom-Bak in European Journal of Applied Physiology
    Article Open access 22 January 2024
  20. An algorithm for visceral leishmaniasis diagnosis in Brazil from a 10-year analysis of National Reference Laboratory data

    Visceral leishmaniasis (VL) requires diagnostic assays to complement clinical suspicion. However, there is no standardization of a diagnostic flow...

    Job Alves de Souza Filho, Marcos Paulo Gomes Mol, Fernanda Alvarenga Cardoso Medeiros in Parasitology Research
    Article 06 January 2024
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