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Radiation pneumonitis prediction with dual-radiomics for esophageal cancer underwent radiotherapy
BackgroundTo integrate radiomics and dosiomics features from multiple regions in the radiation pneumonia (RP grade ≥ 2) prediction for esophageal...
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Radiation pneumonitis prediction after stereotactic body radiation therapy based on 3D dose distribution: dosiomics and/or deep learning-based radiomics features
BackgroundThis study was designed to establish radiation pneumonitis (RP) prediction models using dosiomics and/or deep learning-based radiomics...
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Image masking using convolutional networks improves performance classification of radiation pneumonitis for non-small cell lung cancer
Radiation pneumonitis (RP) is a serious side effect of radiotherapy in patients with locally advanced non-small-cell lung cancer (NSCLC). Image...
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Biological dosiomic features for the prediction of radiation pneumonitis in esophageal cancer patients
ObjectiveThe purpose of this study was to develop a model using dose volume histogram (DVH) and dosiomic features to predict the risk of radiation...
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Analysis of clinical and physical dosimetric factors that determine the outcome of severe acute radiation pneumonitis in lung cancer patients
ObjectiveWe conducted a retrospective statistical analysis of clinical and physical dosimetric factors of lung cancer patients who had previously...
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Novel model integrating computed tomography-based image markers with genetic markers for discriminating radiation pneumonitis in patients with unresectable stage III non-small cell lung cancer receiving radiotherapy: a retrospective multi-center radiogenomics study
BackgroundChemoradiotherapy is a critical treatment for patients with locally advanced and unresectable non-small cell lung cancer (NSCLC), and it is...
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High-dose thoracic radiation therapy for non-small cell lung cancer: a novel grading scale of radiation-induced lung injury for symptomatic radiation pneumonitis
BackgroundSymptomatic radiation pneumonitis (RP) may be a serious complication after thoracic radiation therapy (RT) for non-small cell lung cancer...
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A novel nomogram containing acute radiation esophagitis predicting radiation pneumonitis in thoracic cancer receiving radiotherapy
BackgroundRadiation-induced pneumonitis (RP) is a non-negligible and sometimes life-threatening complication among patients with thoracic radiation....
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Predicting factors of symptomatic radiation pneumonitis induced by durvalumab following concurrent chemoradiotherapy in locally advanced non-small cell lung cancer
BackgroundConcurrent chemoradiotherapy (CCRT) followed by durvalumab is the standard of care for unresectable locally-advanced non-small cell...
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Quantification of preexisting lung ground glass opacities on CT for predicting checkpoint inhibitor pneumonitis in advanced non-small cell lung cancer patients
BackgroundImmune checkpoint inhibitors (ICIs) can lead to life-threatening pneumonitis, and pre-existing interstitial lung abnormalities (ILAs) are a...
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STING signaling activation modulates macrophage polarization via CCL2 in radiation-induced lung injury
BackgroundRadiation-induced lung injury (RILI) is a prevalent complication of thoracic radiotherapy in cancer patients. A comprehensive understanding...
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Radiation pneumonia predictive model for radiotherapy in esophageal carcinoma patients
BackgroundThe machine learning models with dose factors and the deep learning models with dose distribution matrix have been used to building lung...
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Locally advanced NSCLC: a plea for sparing the ipsilateral normal lung—prospective, clinical trial with DART-bid (dose-differentiated accelerated radiation therapy, 1.8 Gy twice daily) by VMAT
BackgroundIn radiation treatment of locally advanced non-small cell lung cancer (LA-NSCLC), ‘margins’ from internal target volumes to planning target...
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CT radiomics-based long-term survival prediction for locally advanced non-small cell lung cancer patients treated with concurrent chemoradiotherapy using features from tumor and tumor organismal environment
BackgroundDefinitive concurrent chemoradiotherapy (CCRT) is the standard treatment for locally advanced non-small cell lung cancer (LANSCLC)...
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Radiomics for prediction of radiation-induced lung injury and oncologic outcome after robotic stereotactic body radiotherapy of lung cancer: results from two independent institutions
ObjectivesTo generate and validate state-of-the-art radiomics models for prediction of radiation-induced lung injury and oncologic outcome in...
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Simulation CT-based radiomics for prediction of response after neoadjuvant chemo-radiotherapy in patients with locally advanced rectal cancer
BackgroundTo report on the discriminative ability of a simulation Computed Tomography (CT)-based radiomics signature for predicting response to...
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Impact of genetic variant of HIPK2 on the risk of severe radiation pneumonitis in lung cancer patients treated with radiation therapy
BackgroundHomeodomain-interacting protein kinase 2 ( HIPK2 ) has increasingly drawn attention as recent researches demonstrated its unique role in the...
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MiRNA let-7i promotes radiation-induced pulmonary epithelial-mesenchymal transition by targeting IL-10
Radiation-induced pulmonary fibrosis (RIPF) is a common complication of thoracic tumors, lacking targeted therapeutic strategies, which seriously...
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Mitigating Radiation Effects on Humans During Space Travel: Recent Developments
Outside Earth’s magnetic field, specifically beyond low Earth orbit, human experiences detrimental effect of space radiations like Galactic cosmic...
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Mitigating Radiation Effects on Humans During Space Travel: Recent Developments
Outside Earth’s magnetic field, specifically beyond low Earth orbit, human experiences detrimental effect of space radiations like Galactic cosmic...