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Antenatal pyelonephritis: a three-year retrospective cohort study of two Irish maternity centres
Pyelonephritis affects 1–2% of pregnant women, and is associated with significant maternal and fetal morbidity. Antenatal pyelonephritis has been...
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Facklamia hominis pyelonephritis in a pediatric patient: first case report and review of the literature
BackgroundPyelonephritis is one of the most serious bacterial illnesses during childhood. Gram-negative organisms account for up to 90% of the cases....
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Increasing rates of extended-spectrum B-lactamase-producing Escherichia coli and Klebsiella pneumoniae in uncomplicated and complicated acute pyelonephritis and evaluation of empirical treatments based on culture results
Increasing rates of extended-spectrum beta-lactamase (ESBL) producing E. coli and K. pneumoniae over time made empirical treatment complicated....
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Exploring the Therapeutic Efficacy of Zingerone Nanoparticles in Treating Biofilm-Associated Pyelonephritis Caused by Pseudomonas aeruginosa in the Murine Model
Biofilms of Pseudomonas aeruginosa can cause complicated urinary tract infections especially in people with indwelling catheters which may result in...
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Modeling the risk of fluoroquinolone resistance in non-severe community-onset pyelonephritis
Estimating whether the individual probability of being infected by a fluoroquinolone resistant isolate is higher than 10% may help to choose the...
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Distribution of papG alleles among uropathogenic Escherichia coli from reproductive age women
BackgroundExtraintestinal Escherichia coli ( E. coli ) causing urinary tract infections (UTIs), and often referred to as uropathogenic E. coli (UPEC),...
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Study on risk factors, bacterial species, and drug resistance of acute pyelonephritis associated with ureteral stent after percutaneous nephrolithotomy
The purpose of this study is to explore the risk factors, bacterial species, and drug resistance of acute pyelonephritis (AP) associated with...
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A pharmacokinetic-pharmacodynamic assessment of oral antibiotics for pyelonephritis
Antibiotic resistance to oral antibiotics recommended for pyelonephritis is increasing. The objective was to determine if there is a pharmacological...
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New Cephalosporins: Fifth and Sixth Generations
New generation (5th) of cephalosporins have been introduced on the market over the last decade to combat methicillin-resistant Staphylococcus aureus...
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Clinical effectiveness of oral antimicrobial therapy for acute pyelonephritis caused by extended-spectrum β-lactamase-producing Enterobacteriales
Infections caused by extended-spectrum β-lactamase - producing Enterobacteriales (ESBL-PE) are commonly treated with intravenous antibiotics. This...
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Inhibition of COX-2 signaling favors E. coli during urinary tract infection
BackgroundTo avoid the overuse of antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), acting via cyclooxygenase (COX) inhibition, have been...
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Clinical impact of perinephric fat stranding detected on computed tomography in patients with acute pyelonephritis: a retrospective observational study
Perinephric fat stranding (PFS) is often detected on computed tomography (CT) in patients with acute pyelonephritis (APN). However, its clinical...
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Differences of virulence factors, and antimicrobial susceptibility according to phylogenetic group in uropathogenic Escherichia coli strains isolated from Korean patients
BackgroundEscherichia coli is among the most common uropathogens. Increased antibiotic resistance in Gram negative bacilli is global concern....
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A systematic review of randomised clinical trials for oral antibiotic treatment of acute pyelonephritis
There is increasing resistance to the oral antibiotics currently recommended for the treatment of pyelonephritis, and increased healthcare costs are...
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Inappropriate empirical antibiotic therapy does not adversely affect the clinical outcomes of patients with acute pyelonephritis caused by extended-spectrum β-lactamase-producing Enterobacteriales
Extended-spectrum β-lactamase-producing Enterobacteriales (ESBL-PE) are often associated with inappropriate empirical therapy (IAT). The aim of this...
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Intercalated cell function, kidney innate immunity, and urinary tract infections
Intercalated cells (ICs) in the kidney collecting duct have a versatile role in acid–base and electrolyte regulation along with the host immune...
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A physiatrist’s role in managing unique challenges in pregnancy and delivery in a patient with incomplete lumbar SCI: a case report
IntroductionWomen of childbearing age make up around 5–10% of individuals with spinal cord injury (SCI) and may face unique medical and functional...
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Management of neurogenic bladder in patients with spinal cord injuries/disorders and end stage renal disease: a case series
IntroductionPatients with spinal cord injuries/disorders (SCI/D) often suffer from bladder dysfunction, commonly referred to as neurogenic bladder or...
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Genetic and Molecular Mechanisms of Multidrug-Resistance in Uropathogens and Novel Therapeutic Combat
Urinary tract infections (UTIs) affect the kidney, ureters, bladder, and urethra. UTIs are divided into pyelonephritis (inflammation of kidney),...