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Nonlinear Methods for the Investigation of Psychotic Disorders
The basic aspects of nonlinear dynamics theory’s utility and impact on understanding psychotic disorders are reviewed and discussed in this chapter....
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Psychotic Disorders (“Schizophrenia”)
After reading the chapter, the reader should be able to name the symptoms of schizophrenia as well as its treatment options and to classify different...
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Brain metabolite levels in remitted psychotic depression with consideration of effects of antipsychotic medication
BackgroundThe neurobiology of psychotic depression is not well understood and can be confounded by antipsychotics. Magnetic resonance spectroscopy...
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Implementation of CYP2D6 copy-number imputation panel and frequency of key pharmacogenetic variants in Finnish individuals with a psychotic disorder
We demonstrate that CYP2D6 copy-number variation (CNV) can be imputed using existing imputation algorithms. Additionally, we report frequencies of...
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A Pilot Study of Adolescents with Psychotic Experiences: Potential Cerebellar Circuitry Disruption Early Along the Psychosis Spectrum
A berrant connectivity in the cerebellum has been found in psychotic conditions such as schizophrenia corresponding with cognitive and motor deficits...
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Blood and CSF anti-neuronal antibodies testing in psychotic syndromes: a retrospective analysis from a tertiary psychiatric hospital
A Consensus of Psychoimmunology Experts ( Pollak et al., 2019) established a set of red flags and proposed diagnostic criteria for psychosis of...
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QEEG and ERP Biomarkers of Psychotic and Mood Disorders and Their Treatment Response
Electroencephalography (EEG) is widely accessible and can be relatively easily applied in clinical settings. This chapter is focused on selected...
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TLR4 Polymorphisms (T399I/D299G) Association with Schizophrenia and Bipolar Disorder in a Tunisian Population
Immune dysregulation has been widely described in the pathophysiology of schizophrenia (SCZ) and bipolar disorder (BD). Particularly, TLR4-altered...
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Evidence of innate immune dysfunction in first-episode psychosis patients with accompanying mood disorder
BackgroundInflammation and increases in inflammatory cytokines are common findings in psychiatric disorders such as schizophrenia (SCZ), bipolar...
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Neuronal pentraxin-2 (NPTX2) serum levels during an acute psychotic episode in patients with schizophrenia
BackgroundNeuronal pentraxin-2 (NPTX2, an immediate-early gene), which regulates synapse activity and neuroplasticity, plays an essential role in the...
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Sestrin-2 and hypoxia-ınducible factor-1 alpha levels in major depressive disorder and its subtypes
BackgroundThe objective of this study is to measure the levels of sestrin-2 (SESN2) and hypoxia-inducible factor-1 alpha (HIF-1α), which can be...
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Persistent Depressive Disorder (Dysthymia) and Recurrent Unipolar Major Depressive Disorder
The term depression comes from the Latin “depressio” and indicates a state of dejection perceived by the subject accompanied by extreme suffering and...
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Gray matter abnormalities in patients with major depressive disorder and social anxiety disorder: a voxel-based meta-analysis
BackgroundMajor depressive and social anxiety disorders have a high comorbidity rate and similar cognitive patterns. However, their unique and shared...
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Psychotic Disorders in Epilepsy: Do They Differ from Primary Psychosis?
Any attempt to compare the definitions of symptoms listed for “primary psychoses” with those adopted in studies of psychoses in patients with...
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Psychotic Disorders in the Veterans of Local Wars
Objectives. To determine the frequency of leading psychopathological syndromes, dynamics, and comorbidities of schizophrenia and other endogenous...
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Lipopolysaccharide Exacerbates Ketamine-Induced Psychotic-Like Behavior, Oxidative Stress, and Neuroinflammation in Mice: Ameliorative Effect of Diosmin
Schizophrenia, a neuropsychiatric disorder has been associated with aberrant neurotransmission affecting behaviors, social preference, and cognition....
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Lithium, the gold standard drug for bipolar disorder: analysis of current clinical studies
Lithium is the gold standard drug in the treatment of bipolar disorder. Despite increasing scientific interest, relatively few patients with bipolar...
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Progress and Implications from Genetic Studies of Bipolar Disorder
With the advancements in gene sequencing technologies, including genome-wide association studies, polygenetic risk scores, and high-throughput...
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Drug-Induced Gambling Disorder: Epidemiology, Neurobiology, and Management
Problematic gambling has been suggested to be a possible consequence of dopaminergic medications used mainly in neurological conditions, i.e....