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1. Effects of Combined Exposure to Carbon Ions and Protons on the Pool of MCF-7 Breast Cancer Stem Cells In Vitro

   We studied the effects of single and combined action of protons and carbon ions ¹² C ⁶⁺ on the pool of MCF-7 human breast cancer stem cells. Single...

   O. N. Matchuk, E. I. Selivanova, ... I. A. Zamulaeva in Bulletin of Experimental Biology and Medicine

   Article 01 November 2023

2. Triggering of Major Brain Disorders by Protons and ATP: The Role of ASICs and P2X Receptors

   Adenosine triphosphate (ATP) is well-known as a universal source of energy in living cells. Less known is that this molecule has a variety of...

   Andrii Cherninskyi, Maksim Storozhuk, ... Oleg Krishtal in Neuroscience Bulletin

   Article 29 November 2022
   

3. DNA Damage in Splenocytes of Mice Exposed to Secondary Radiation Created by 650 MeV Protons Bombarding a Concrete Shielding Barrier

   The proportion of splenocytes with a high level of DNA double-strand breaks was determined in mice exposed to primary and secondary radiation created...

   T. M. Blokhina, A. A. Ivanov, ... A. N. Osipov in Bulletin of Experimental Biology and Medicine

   Article 01 December 2022

4. Ratiometric Recognition of Protons by a Multiple Tagged Designer Fluorescent Chemosensor

   Molecular architecture with different fluorophoric units can offer improved and effective recognition of biologically important analytes. We present...

   Vaishali Khokhar, Hanuman Singh, ... Siddharth Pandey in Journal of Fluorescence

   Article 22 June 2022
   

5. Biological Response of Chinese Hamster B14-150 Cells to Sequential Combined Exposure to Protons and ¹²C Ions

   Proton and ion radiation therapy, when used both as single radiation and in mixed radiation mode, have a number of advantages over the conventional...

   M. V. Troshina, E. V. Koryakina, ... S. N. Koryakin in Bulletin of Experimental Biology and Medicine

   Article 01 November 2023

6. HYpofractionated, dose-redistributed RAdiotherapy with protons and photons to combat radiation-induced immunosuppression in head and neck squamous cell carcinoma: study protocol of the phase I HYDRA trial

   Background

   Radiotherapy (RT) is the standard of care for most advanced head and neck squamous cell carcinoma (HNSCC) and results in an unfavorable...

   Joris B. W. Elbers, Pascal A. Gunsch, ... Remi A. Nout in BMC Cancer

   Article Open access 13 June 2023
   

7. How protons pave the way to aggressive cancers

   Cancers undergo sequential changes to proton (H ⁺ ) concentration and sensing that are consequences of the disease and facilitate its further...

   Pawel Swietach, Ebbe Boedtkjer, Stine Falsig Pedersen in Nature Reviews Cancer

   Article 26 October 2023
   

8. Copper Ions Reduce the Effect of Protons on Desensitization of Glycine Receptors

   Chloride current (I _Gly ) evoked by the rapid (600 msec) application of glycine on isolated pyramidal neurons of the rat hippocampus was recorded using...

   E. I. Solntseva, J. V. Bukanova, ... V. G. Skrebitsky in Bulletin of Experimental Biology and Medicine

   Article 24 October 2020

9. Dosimetric evaluation of photons versus protons in postmastectomy planning for ultrahypofractionated breast radiotherapy

   Background

   Ultrahypofractionation can shorten the irradiation period. This study is the first dosimetric investigation comparing...

   Puntiwa Oonsiri, Chonnipa Nantavithya, ... Kitwadee Saksornchai in Radiation Oncology

   Article Open access 29 January 2022
   

10. Effect of Protons on GABA_A Receptors in Central Neurons of Various Types

    Whole-cell patch-clamp technique was employed to record chloride ionic current I _GABA evoked by fast (600 msec) application of GABA to hippocampal...

    E. I. Solntseva, Yu. V. Bukanova, V. G. Skrebitsky in Bulletin of Experimental Biology and Medicine

    Article 01 February 2020

11. Development of a portable hypoxia chamber for ultra-high dose rate laser-driven proton radiobiology applications

    Background

    There is currently significant interest in assessing the role of oxygen in the radiobiological effects at ultra-high dose rates. Oxygen...

    Pankaj Chaudhary, Deborah C. Gwynne, ... Marco Borghesi in Radiation Oncology

    Article Open access 15 April 2022
    

12. Post-Irradiation Recovery of B14-150 Fibrosarcoma Cells after Combined Irradiation with Low and High Linear Energy Transfer

    The use of radiation with low and high linear energy transfer (LET) in the same treatment regimen is promising in terms of increasing the efficiency...

    E. V. Koryakina, V. I. Potetnya, ... A. D. Kaprin in Bulletin of Experimental Biology and Medicine

    Article 01 September 2022

13. Acid-sensing ion channels and downstream signalling in cancer cells: is there a mechanistic link?

    It is increasingly appreciated that the acidic microenvironment of a tumour contributes to its evolution and clinical outcomes. However, our...

    Stefan Gründer, Jakob Vanek, Karolos-Philippos Pissas in Pflügers Archiv - European Journal of Physiology

    Article Open access 04 January 2024
    

14. β-Amyloid Peptide Antagonizes the Effect of Protons on Taurine-Induced Chloride Current in Rat Hippocampal Pyramidal Neurons

    Taurine is an important endogenous agonist of glycine receptors (GlyR). Using the patchclamp technique, we measured chloride current induced by a...

    E. I. Solntseva, Yu. V. Bukanova, ... V. G. Skrebitsky in Bulletin of Experimental Biology and Medicine

    Article 15 June 2019

15. Comparative Analysis of Behavioral Reactions and Morphological Changes in the Rat Brain After Exposure to Ionizing Radiation with Different Physical Characteristics

    The aim of this research was to study behavioral reactions and morphological changes in the brain of adult female Sprague Dawley rats after exposure...

    Yu. S. Severyukhin, M. Lalkovičová, ... E. A. Krasavin in Cellular and Molecular Neurobiology

    Article 04 January 2022
    

16. Severely polarized extracellular acidity around tumour cells

    Extracellular pH impacts many molecular, cellular and physiological processes, and hence is tightly regulated. Yet, in tumours, dysregulated cancer...

    Qiang Feng, Zachary Bennett, ... **ming Gao in Nature Biomedical Engineering

    Article 04 March 2024
    

17. Preparation and Spectroscopic Characterization of Inclusion Complexes of 3D Ball-Milled Rifampicin with β-cyclodextrin and γ-cyclodextrin

    Rifampicin (RFP) solutions, intended to reduce incidence of prosthetic graft infection, were prepared as three-dimensional ground mixtures (3DGMs)...

    Yutaka Inoue, Mari Shigematsu, ... Gerard Lee See in AAPS PharmSciTech

    Article 09 May 2022
    

18. Role of the Voltage-Gated Proton Channel Hv1 in Nervous Systems

    Hv1 is the only voltage-gated proton-selective channel in mammalian cells. It contains a conserved voltage-sensor domain, shared by a large class of...

    Yu Shen, Yuncheng Luo, ... Ruotian Jiang in Neuroscience Bulletin

    Article 08 April 2023
    

19. Experimental and Theoretical Studies of Fluorescent “Turn Off” Sensor Functionalized With Carboxylic Acid and Naphthalene Group for Selective Detection of 2,4,6-Trinitrophenol

    A fluorescent sensor, 5-((2-hydroxynaphthalen-1-yl)methyleneamino)benzene-1,3-dicarboxylic acid (coded as SB), containing both π-π interacting sites...

    Manpreet Kaur in Journal of Fluorescence

    Article 24 July 2023
    

20. Spectroscopy: Principle, Types and Microbiological Applications

    Spectroscopy is a study of the absorption and emission of light and other radiation by substances related to the wavelength dependence of...

    Santi M. Mandal, Debarati Paul in Automation and Basic Techniques in Medical Microbiology

    Chapter 2022