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Akimba Proliferative Diabetic Retinopathy Model: Understanding Molecular Mechanism and Drug Screening for the Progression of Diabetic Retinopathy
As the prevalence of diabetes has reached epidemic proportions worldwide, diabetic retinopathy incidence is increasing rapidly. An advanced diabetic...
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TET2-mediated ECM1 hypomethylation promotes the neovascularization in active proliferative diabetic retinopathy
BackgroundStudies have shown that tet methylcytosine dioxygenase 2 (TET2) is highly expressed in diabetic retinopathy (DR), which reduces the DNA...
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Microglia in retinal angiogenesis and diabetic retinopathy
Diabetic retinopathy has a high probability of causing visual impairment or blindness throughout the disease progression and is characterized by the...
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Bioinformatics Tools for Bulk Gene Expression Deconvolution in Diabetic Retinopathy
Retinal neovascularization is one of the leading causes of vision loss and a hallmark of proliferative diabetic retinopathy (PDR). The immune system...
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Association of monocyte-lymphocyte ratio and proliferative diabetic retinopathy in the U.S. population with type 2 diabetes
ObjectiveDiabetic retinopathy (DR), especially proliferative diabetic retinopathy (PDR) is a common cause of blindness and visual impairment. Early...
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Short communication: unique metabolic signature of proliferative retinopathy in the tear fluid of diabetic patients with comorbidities — preliminary data for PPPM validation
Type 2 diabetes (T2DM) defined as the adult-onset type that is primarily not insulin-dependent, comprises over 95% of all diabetes mellitus (DM)...
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Enhancing deep learning pre-trained networks on diabetic retinopathy fundus photographs with SLIC-G
AbstractDiabetic retinopathy disease contains lesions (e.g., exudates, hemorrhages, and microaneurysms) that are minute to the naked eye. Determining...
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Oxygen-Induced Retinopathy in the Rat: An Animal Model to Study the Proliferative Retinal Vascular Pathology
Diabetic retinopathy (DR) is one of the leading causes of vision loss worldwide. There are numerous animal models available for develo** new ocular...
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Diabetic retinopathy: emerging concepts of current and potential therapy
Diabetic retinopathy (DR) is one of the leading causes of permanent central blindness worldwide. Despite the complexity and inadequate understanding...
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Macrophage activation contributes to diabetic retinopathy
Diabetic retinopathy (DR) is recognized as a neurovascular complication of diabetes, and emerging evidence underscores the pivotal role of...
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Exploring various novel diagnostic and therapeutic approaches in treating diabetic retinopathy
Diabetic retinopathy is regarded as a common manifestation of diabetes mellitus, being a prominent cause of visual impairment and blindness. This...
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Diabetic retinopathy as the leading cause of blindness and early predictor of cascading complications—risks and mitigation
Proliferative diabetic retinopathy (PDR) the sequel of diabetic retinopathy (DR), a frequent complication of diabetes mellitus (DM), is the leading...
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DEC-DRR: deep ensemble of classification model for diabetic retinopathy recognition
AbstractMost diabetes patients are liable to have diabetic retinopathy (DR); however, the majority of them might not be even aware of the ailment....
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A New Modulator of Neuroinflammation in Diabetic Retinopathy: USP25
Diabetic retinopathy (DR) is a diabetes-associated complication that poses a threat to vision, distinguished by persistent and mild inflammation of...
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Statins as a risk factor for diabetic retinopathy: a Mendelian randomization and cross-sectional observational study
BackgroundDiabetic retinopathy (DR) is the foremost cause of vision loss among the global working-age population, and statins are among the most...
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Serum Vitamin D As a Biomarker in Diabetic: Applications and Associations with Retinopathy
Vitamin D is a multifunctional hormone with multiple biological functions including regulation of endothelial function, angiogenesis, antioxidant and...
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A deep learning system for predicting time to progression of diabetic retinopathy
Diabetic retinopathy (DR) is the leading cause of preventable blindness worldwide. The risk of DR progression is highly variable among different...
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A Guide to Genome-Wide Association Study Design for Diabetic Retinopathy
Diabetic retinopathy (DR) is the most common microvascular complication related to diabetes. There is evidence that genetics play an important role...
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Recognition of diabetic retinopathy and macular edema using deep learning
Diabetic retinopathy (DR) and diabetic macular edema (DME) are both serious eye conditions associated with diabetes and if left untreated, and they...
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Uncovering the Therapeutic Potential of Phosphocreatine in Diabetic Retinopathy: Mitigating Mitochondrial Dysfunction and Apoptosis via JAK2/STAT3 Signaling Pathway
Diabetic retinopathy (DR) stands as a prevalent complication of diabetes mellitus, causing damage to the delicate retinal capillaries and potentially...
