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Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records
BackgroundVasomotor symptoms (VMS) can often significantly impact women’s quality of life at menopause. In vivo studies have shown that increased...
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Clinical Validation of a Primary Antibody Deficiency Screening Algorithm for Primary Care
PurposeThe diagnostic delay of primary antibody deficiencies (PADs) is associated with increased morbidity, mortality, and healthcare costs....
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A digital health algorithm to guide antibiotic prescription in pediatric outpatient care: a cluster randomized controlled trial
Excessive antibiotic use and antimicrobial resistance are major global public health threats. We developed ePOCT+, a digital clinical decision...
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Failure to follow up abnormal test results associated with cervical cancer in primary and ambulatory care: a systematic review
BackgroundCervical cancer is a preventable and treatable form of cancer yet continues to be the fourth most common cancer among women globally....
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Patterns and outcomes of health-care associated infections in the medical wards at Bugando medical centre: a longitudinal cohort study
BackgroundThe burden of healthcare associated infections (HCAIs) in low- and middle-income countries (LMICs) remains underestimated due to diagnostic...
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Perspectives of primary care physicians in Spain on malaria: a cross-sectional survey and retrospective review of cases
BackgroundIn Spain, the risk of imported malaria has increased in recent years due to the rise in international travel and migration. Little is known...
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Excess use of thyroid hormone treatment among patients with fibromyalgia: a cross-sectional study in primary health care
ObjectiveFrom previous studies, it is known that the association between fibromyalgia and thyroid autoimmunity diseases exists. On the other hand, it...
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Antimicrobial stewardship in rural and remote primary health care: a narrative review
BackgroundAntimicrobial resistance is an emerging problem worldwide and poses a significant threat to human health. Antimicrobial stewardship...
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Capacities and needs of health care facilities for schistosomiasis diagnosis and management in elimination settings
BackgroundSchistosomiasis is a debilitating neglected tropical disease endemic in sub-Saharan Africa. The role of health facilities in the...
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Effects of the COVID-19 pandemic on general health and malaria control in Ghana: a qualitative study with mothers and health care professionals
BackgroundCOVID-19 has severely impacted health systems and the management of non-COVID-19 diseases, including malaria, globally. The pandemic has...
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Pathways to Mental Health Care in a Defined Geographic Area of Athens
The purpose of the present study was to explore the duration between the onset of psychopathology and the first contact either with a sectorized...
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Health care seeking behaviour towards cervical cancer screening among women aged 30–49 years in Arbaminch town, Southern Ethiopia, 2023
BackgroundCervical cancer is a preventable disease. However, it remains the commonest and deadly cancer in women worldwide. Health care seeking...
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Views of health care users and providers: Solutions to improve the prevention of secondary health conditions among people with spinal cord injury, South Africa
Study designExplorative- qualitative study.
ObjectiveThis study explored solutions to improve the prevention of secondary health conditions in...
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Health-related quality of life and its associated factors among hemophilia patients: experience from Ethiopian Hemophilia Treatment Centre
BackgroundHemophilia is a rare genetic condition that is often overlooked and underdiagnosed, particularly in low-income countries. Long-term...
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Supporting Decarbonization of Health Systems—A Review of International Policy and Practice on Health Care and Climate Change
Purpose of ReviewHealthcare is a significant contributor of carbon emissions, which contribute to climate change. There has been an increased focus...
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The stepwise process of integrating a genetic counsellor into primary care
Genetic services have historically been housed in tertiary care, requiring referral, which can present access barriers. While integrating genetics...
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ctDNA guided adjuvant chemotherapy versus standard of care adjuvant chemotherapy after curative surgery in patients with high risk stage II or stage III colorectal cancer: a multi-centre, prospective, randomised control trial (TRACC Part C)
BackgroundCirculating tumour DNA (ctDNA) to detect minimal residual disease (MRD) is emerging as a biomarker to predict recurrence in patients with...
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Organization of Palliative Care in Different Parts of the World
Palliative care has developed rapidly and heterogeneously in the past decade around the globe. In this chapter, we present an overview of palliative...
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The effect of breathing exercises and mindset with or without cold exposure on mental and physical health in persons with a spinal cord injury—a protocol for a three-arm randomised-controlled trial
Study designA three-arm randomized controlled trial.
ObjectivesTo investigate the effects of the Wim Hof Method (WHM), with (WHM-C) and without cold...
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