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Perioperative Assessment and Management of Patients with Sleep Disorders
In the United States, about 60,000 patients receive general anesthesia for surgery per day. The most important postoperative cardiac, neurologic, and...
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COVID Pandemic Impact on OSA and Other Sleep Disorders
The COVID-19 pandemic is the deadliest one in human history. The unprecedented changes it brought in human lifestyle, health, economy, business,...
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Esketamine Prevents Postoperative Emotional and Cognitive Dysfunction by Suppressing Microglial M1 Polarization and Regulating the BDNF-TrkB Pathway in Ageing Rats with Preoperative Sleep Disturbance
Postoperative depression (POD) and postoperative cognitive dysfunction (POCD) have placed heavy burden on patients’ physical and mental health in...
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Emerging Insights into Postoperative Neurocognitive Disorders: The Role of Signaling Across the Gut-Brain Axis
The pathophysiological regulatory mechanisms in postoperative neurocognitive disorders (PNCDs) are intricately complex. Currently, the pathogenesis...
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Preoperative Acute Sleep Deprivation Causes Postoperative Pain Hypersensitivity and Abnormal Cerebral Function
Preoperative sleep loss can amplify post-operative mechanical hyperalgesia. However, the underlying mechanisms are still largely unknown. In the...
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Downregulation of the glucose transporter GLUT 1 in the cerebral microvasculature contributes to postoperative neurocognitive disorders in aged mice
IntroductionGlucose transporter 1 (GLUT1) is essential for glucose transport into the brain and is predominantly expressed in the cerebral...
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Prediction of risk factors of sleep disturbance in patients undergoing total hip arthroplasty
The purpose of this study was to assess sleep quality in patients undergoing total hip arthroplasty (THA) from preoperatively to 12 weeks...
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A Prospective Study Evaluating Sleep Quality and Disorders in Post-ARDS Patients
IntroductionCritically ill patients are predisposed to develo** sleep disorders due to multiple factors like pre-existing sleep disorders, severe...
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The Thalamus in Perioperative Neurocognitive Disorders
Thalamus function and structure are known predictors of individual differences in the risk of age-related neurocognitive disorders (NCD), such as...
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Basal ganglia engagement during REM sleep movements in Parkinson’s disease
To elucidate the role of the basal ganglia during REM sleep movements in Parkinson’s disease (PD) we recorded pallidal neural activity from four PD...
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Effects of multiple exposures to general anesthesia on the sleep quality of children after plastic surgery in Bei**g, China: a cohort study
To assess the effects of the number and duration of general anesthesia exposure on the sleep quality of 6–15-year-old school children who underwent...
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Sleep in Critically Ill Patient
Sleep is an essential physiological need that allows body and mind to recharge, alert, and restore health which is regulated by circadian rhythm....
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Efficacy of combined use of Suvorexant and Ramelteon in preventing postoperative delirium: a retrospective comparative study
BackgroundSuvorexant and ramelteon have been presented as useful for preventing postoperative delirium. Previous studies reported on the comparison...
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The Role of the Intestinal Flora and Its Derivatives in Neurocognitive Disorders: A Narrative Review from Surgical Perspective
Perioperative neurocognitive dysfunction is a significant concern for population health, impacting postoperative recovery and increasing the...
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Strong opioids-induced cardiac, neurologic, and respiratory disorders: a real-world study from 2004 to 2023 based on FAERS
Opioids are mainly used as adjuncts to the induction and maintenance of general anesthesia, postoperative analgesia, and treating moderate to severe...
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Melatonin and Health: Insights of Melatonin Action, Biological Functions, and Associated Disorders
Melatonin is ubiquitous molecule with wide distribution in nature and is produced by many living organisms. In human beings, pineal gland is the...
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Sleep and cancer recurrence and survival in patients with resected Stage III colon cancer: findings from CALGB/SWOG 80702 (Alliance)
BackgroundWe sought to assess the influences of sleep duration, sleep adequacy, and daytime sleepiness on survival outcomes among Stage III colon...
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History, Origin and Types of Neurological Disorders
Neurological disorders generally affect the brain and spinal cord as well as the nerves found throughout the body. These disorders might result in...
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Augmenting hippocampal–prefrontal neuronal synchrony during sleep enhances memory consolidation in humans
Memory consolidation during sleep is thought to depend on the coordinated interplay between cortical slow waves, thalamocortical sleep spindles and...
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STING Agonist cGAMP Attenuates Sleep Deprivation-Induced Neuroinflammation and Cognitive Deficits via TREM2 Up-Regulation
Sleep deprivation (SD) has been associated with several adverse effects, including cognitive deficit. Emerging evidence suggests microglia-associated...
