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Effect of Material Properties and Variability of Mannitol on Tablet Formulation Development
PurposeUsing a high level of mannitol as a diluent in oral formulations can potentially result in tablet defects (e.g., chip**, cracking) during...
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Design considerations for patient-specific bone fixation plates: a literature review
In orthopedic surgery, patient-specific bone plates are used for fixation when conventional bone plates do not fit the specific anatomy of a patient....
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A Musculoskeletal Model for Estimating Hip Contact Pressure During Walking
Cartilage contact pressures are major factors in osteoarthritis etiology and are commonly estimated using finite element analysis (FEA). FEA models...
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Injectable and conductive cardiac patches repair infarcted myocardium in rats and minipigs
Cardiac patches can help to restore the electrophysiological properties of the heart after myocardial infarction. However, scaffolds for the repair...
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Numerical simulation-based loaded inflation height modeling of nursing bed airbag
In previous studies, the numerical simulation models of industrial airbags were verified to have high accuracy regarding their actual dynamics....
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Hydraulic resistance of three-dimensional pial perivascular spaces in the brain
BackgroundPerivascular spaces (PVSs) carry cerebrospinal fluid (CSF) around the brain, facilitating healthy waste clearance. Measuring those flows in...
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A New Method for Predicting the Porosity of an Interbody Fusion Cage by the Equivalent Material Method
PurposeThe interbody fusion cage will cause stress shielding problems due to its material characteristics. This paper aims to find out the change in...
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Modelling Pile-Driving Sound and Mitigation in Realistic Environments
Impact pile driving is a transient anthropogenic underwater sound source that can potentially affect marine life. Mathematical modelling tools are... -
Biomechanical Finite Element Analysis of Bone Tissues with Different Scales in the Bone Regeneration Area after Scoliosis Surgery
PurposeThis paper aims to analyze the influence of mechanical force on bone regeneration from macro and micro perspectives, to investigate the...
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A macro–micro FE and ANN framework to assess site-specific bone ingrowth around the porous beaded-coated implant: an example with BOX® tibial implant for total ankle replacement
The use of mechanoregulatory schemes based on finite element (FE) analysis for the evaluation of bone ingrowth around porous surfaces is a viable...
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Multi-Objective Optimization of Bioresorbable Magnesium Alloy Stent by Kriging Surrogate Model
PurposeThe study proposed a multi-objective optimization method based on Kriging surrogate model and finite element analysis to mitigate the redial...
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Analysis of Fatigue Strength and Reliability of Lower Limb Arterial Stent at Different Vascular Stenosis Rates and Stent-to-Artery Ratios
In order to study the influence of different vascular stenosis rates and stent-to-artery ratios on the fatigue strength and reliability of lower limb...
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Sizes and shapes of perivascular spaces surrounding murine pial arteries
BackgroundFlow of cerebrospinal fluid (CSF) through brain perivascular spaces (PVSs) is essential for the clearance of interstitial metabolic waste...
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Subject-Specific Geometry of FE Lumbar Spine Models for the Replication of Fracture Locations Using Dynamic Drop Tests
For traumatic lumbar spine injuries, the mechanisms and influence of anthropometrical variation are not yet fully understood under dynamic loading....
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Droplet Digital PCR-Based Diagnosis for Porcine Viral Diseases
Polymerase chain reaction (PCR) is a common and indispensable technique that has been employed since its discovery for the diagnosis of infectious... -
Microstructural fatigue fracture behavior of glycated cortical bone
AbstractThe current study aims to simulate fatigue microdamage accumulation in glycated cortical bone with increased advanced glycation end-products...
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Evaluation of heat transfer in porous scaffolds under cryogenic treatment: a numerical study
The present work had evaluated the effect of cryogenic treatment (233 K) on the degradation of polymeric biomaterial using a numerical model. The...
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Forward Models
This chapter treats the neuroelectromagnetic forward problem, which describes the prediction of EEG or MEG signals from the parameters of the source... -
Biomechanical Analysis of Mandibular Implant-Assisted Removable Partial Denture with Distal Extension
PurposeThis study aimed to evaluate the mechanical performance of mandibular implant-assisted removable partial dentures (IARPDs) on abutment teeth,...
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An Improved Finite Element Model of Temporomandibular Joint in Maxillofacial System: Experimental Validation
Finite element (FE) analysis has become a popular method of exploring the biomechanical characteristics of temporomandibular joint (TMJ). However,...