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Molecular detection and phylogenic characterization of Neospora caninum in naturally infected sheep in Alborz and Qazvin provinces, the north of the central region of Iran
Neospora caninum is a protozoan coccidian parasite that can act as a cause of abortion in sheep. The aim of this study was to investigate the...
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Mitogen-Activated Protein Kinase and Aquaglyceroporin Gene Expression in Treatment Failure Leishmania major
PurposeLeishmaniasis comprises various clinical forms mainly including cutaneous, muco-cutaneous, and visceral leishmaniasis; caused by Leishmania ...
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Geographical and Molecular Analysis of Haplotype Variations in Leishmania major Among Infected Iranian Phlebotomus papatasi
PurposeLeishmania major is main causative agent and Phlebotomus papatasi is only proven vector of Zoonotic Cutaneous Leishmaniasis (ZCL) in Iran....
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DNA Barcoding and Phylogenetic Analysis of Ceylon Oak with Other Fruit Plants in Sapindaceae Family
Ceylon oak ( Schleichera oleosa (Lour.) Oken), belonging to Sapindaceae family, is a widely used plant for its medicinal properties. Currently, few...
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Genetic characterization and evolutionary analysis of canine parvovirus in Tangshan, China
Canine parvovirus (CPV) is a major enteric virus of carnivores worldwide that poses a considerable threat to dogs. In this study, we investigated the...
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Characterization and genomic analysis of a novel bacteriophage BUCT_49532 lysing Klebsiella pneumoniae
Bacteriophages are a type of virus widely distributed in nature that demonstrates a remarkable aptitude for selectively recognizing and infecting...
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The great gerbil (Rhombomys opimus) as a host for tick species in Gurbantunggut Desert
BackgroundRodents play an important role in the life cycle of ixodid and argasid ticks, particularly as hosts of larvae and nymphs. The great gerbil (
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Association of disease severity and genetic variation during primary Respiratory Syncytial Virus infections
BackgroundRespiratory Syncytial Virus (RSV) disease in young children ranges from mild cold symptoms to severe symptoms that require hospitalization...
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The heterogeneity and clonal evolution analysis of the advanced prostate cancer with castration resistance
BackgroundNowadays, the incidence rate of advanced and metastatic prostate cancer at the first time of diagnosis grows higher in China yearly. At...
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Comparative Analysis on the Codon Usage Pattern of the Chloroplast Genomes in Malus Species
Codon usage bias of coding sequences has been usually used for exploring the evolutionary factors that affect the variation of genes. We took 20...
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In Silico Prediction of MYO1C-Rhodopsin Interactions and Its Significance in Protein Localization and Visual Function
Rods and cones are photoreceptor neurons in the retina that are required for visual sensation in vertebrates, where proper protein localization and... -
Whole-genome analysis of coxsackievirus B3 reflects its genetic diversity in China and worldwide
BackgroundCoxsackievirus B3 (CVB3) has emerged as an active pathogen in myocarditis, aseptic meningitis, hand, foot, and mouth disease (HFMD), and...
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COVID-19: A novel holistic systems biology approach to predict its molecular mechanisms (in vitro) and repurpose drugs
PurposeCOVID-19 strangely kills some youth with no history of physical weakness, and in addition to the lungs, it may even directly harm other...
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Immunogenicity of MultiTEP platform technology-based Tau vaccine in non-human primates
Pathological forms of Tau protein are directly associated with neurodegeneration and correlate with Alzheimer’s Disease (AD) symptoms, progression,...
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Phylogenetic analysis of HA and NA genes of influenza A viruses in immunosuppressed inpatients in Bei**g during the 2018–2020 influenza seasons
BackgroundInfluenza A viruses have undergone rapid evolution with virulent; however, complete and comprehensive data on gene evolution and amino acid...
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Phylogenetic analysis of classical swine fever virus isolates from China
Classical swine fever (CSF), caused by classical swine fever virus (CSFV), is a severe disease that causes huge economic losses in the swine industry...
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Genetic changes and evolutionary analysis of canine circovirus
Canine circovirus (canineCV) has been found to be associated with vasculitis, hemorrhage, hemorrhagic enteritis, and diarrhea of canines. CanineCV,...
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Various arrangements of mobile genetic elements among CC147 subpopulations of Klebsiella pneumoniae harboring blaNDM-1: a comparative genomic analysis of carbapenem resistant strains
BackgroundCertain clonal complexes (CCs) of Klebsiella pneumoniae such as CC147 (ST147 and ST392) are major drivers of bla NDM dissemination across...
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Molecular and hematological investigation of Trypanosoma evansi infection in Iranian one-humped camels (Camelus dromedarius)
Trypanosoma species cause animal trypanosomiasis that infects many animals. Trypanosoma evansi is an organism that infects camels. There are many...
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A subfamily of the small heat shock proteins of the marine red alga Neopyropia yezoensis localizes in the chloroplast
Small heat shock proteins (sHSPs) play a crucial role under abiotic stress and are present in all organisms, from eukaryotes to prokaryotes. However,...