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Vagus Nerve Stimulation in Peripheral Targets
Although vagus nerve stimulation (VNS) is nowadays frequently used in the treatment of neuropsychiatric disorders including epilepsy, depression, and...
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Enhanced peripheral nerve regeneration by mechano-electrical stimulation
To address limitations in current approaches for treating large peripheral nerve defects, the presented study evaluated the feasibility of functional...
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Repetitive high-sustained gravitoinertial stress does not modulate pressure responsiveness to peripheral sympathetic stimulation
PurposeWe evaluated the hypothesis that repetitive gravitoinertial stress would augment the arterial-pressure response to peripheral sympathetic...
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Synergistic efficacy of repetitive peripheral magnetic stimulation on central intermittent theta burst stimulation for upper limb function in patients with stroke: a double-blinded, randomized controlled trial
BackgroundNon-invasive techniques such as central intermittent theta burst stimulation (iTBS) and repetitive peripheral magnetic stimulation (rPMS)...
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CD40 ligand stimulation affects the number and memory phenotypes of human peripheral CD8+ T cells
BackgroundCD40L is primarily expressed on activated CD4 + T cells and binds to CD40 which is expressed by various cells including dendritic cells,...
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A wireless millimetric magnetoelectric implant for the endovascular stimulation of peripheral nerves
Implantable bioelectronic devices for the simulation of peripheral nerves could be used to treat disorders that are resistant to traditional...
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Identifying and modulating distinct tremor states through peripheral nerve stimulation in Parkinsonian rest tremor
BackgroundResting tremor is one of the most common symptoms of Parkinson’s disease. Despite its high prevalence, resting tremor may not be as...
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Cytokine producing ability of peripheral blood cells from COVID-19 patients after unspecific in vitro stimulation
Objective and designPerturbations of peripheral T cell homeostasis and dysregulation of the immune response to SARS-CoV-2, especially in severely ill...
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Peripheral magnetic theta burst stimulation to muscles can effectively reduce spasticity: a randomized controlled trial
BackgroundSpasticity is a common complication of many neurological diseases and despite contributing much disability; the available therapeutic...
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Mechanistically informed non-invasive peripheral nerve stimulation for peripheral neuropathic pain: a randomised double-blind sham-controlled trial
BackgroundInduction of long-term synaptic depression (LTD) is proposed as a treatment mechanism for chronic pain but remains untested in clinical...
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Chronic electrical stimulation of peripheral nerves via deep-red light transduced by an implanted organic photocapacitor
Implantable devices for the wireless modulation of neural tissue need to be designed for reliability, safety and reduced invasiveness. Here we report...
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Stimulation parameters for directional vagus nerve stimulation
BackgroundAutonomic nerve stimulation is used as a treatment for a growing number of diseases. We have previously demonstrated that application of...
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Obstructive sleep apnea improves with non-invasive hypoglossal nerve stimulation using temporal interference
BackgroundPeripheral nerve stimulation is used in both clinical and fundamental research for therapy and exploration. At present, non-invasive...
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Peripheral blood amyloid-β involved in the pathogenesis of Alzheimer’s disease via impacting on peripheral innate immune cells
A key pathological factor of Alzheimer’s disease (AD), the most prevalent form of age-related dementia in the world, is excessive β-amyloid protein...
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Repetitive Noxious Stimulation with Formalin, Capsaicin, and Freund’s Adjuvant Facilitates Monitoring of the Peripheral and Central Pain Effects
AbstractPain is one of the most frequent symptoms accompanying diseases. Every type of pain invokes various molecular mechanisms leading to the...
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Peripheral electrical stimulation to reduce pathological tremor: a review
Interventions to reduce tremor in essential tremor (ET) and Parkinson’s disease (PD) clinical populations often utilize pharmacological or surgical...
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Automated calibration of somatosensory stimulation using reinforcement learning
BackgroundThe identification of the electrical stimulation parameters for neuromodulation is a subject-specific and time-consuming procedure that...
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A Novel Paired Somatosensory-Cerebellar Stimulation Induces Plasticity on Cerebellar-Brain Connectivity
The cerebellum receives and integrates a large amount of sensory information that is important for motor coordination and learning. The aim of the...
