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Unipolar Depressive Disorders: A Gender-Based Comparative Analysis
Objective. To carry out a comparative analysis of social-demographic and clinical-psychopathological characteristics of male and female patients with...
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DNA methylation associated with postpartum depressive symptoms overlaps findings from a genome-wide association meta-analysis of depression
BackgroundPerinatal depressive symptoms have been linked to adverse maternal and infant health outcomes. The etiology associated with perinatal...
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Early Life Stress, Neuroinflammation, and Psychiatric Illness of Adulthood
Stress exposure during early stages of life elevates the risk of develo** psychopathologies and psychiatric illness in later life. The brain and...
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Perinatal Psychiatry: Ready for Prime Time?
Perinatal psychiatry deals primarily with women’s mental health before labor and up to the first year post-childbirth and the growth and development...
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A stable and replicable neural signature of lifespan adversity in the adult brain
Environmental adversities constitute potent risk factors for psychiatric disorders. Evidence suggests the brain adapts to adversity, possibly in an...
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Acceptance and Commitment Therapy for Major Depressive Disorder: Insights into a New Generation of Face-to-Face Treatment and Digital Self-Help Approaches
Major depressive disorder (MDD) represents a key contributor to the global burden of mental illness given its relatively high lifetime prevalence,...
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Intergenerational Aspects of Immune and Endocrine Function in Perinatal Depression
Perinatal depression mediates a profound impact on maternal and offspring health. Alterations in endocrine and immune function in depressed mothers...
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Epigenetic Modifications of Early-Life Stress and Adult Life Psychopathology
There is much evidence linking adverse conditions during early life to risk of develo** mood disorders in later life. Exposures to high levels of...
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Ontogeny of the Corticolimbic System and the Risk of Anxiety Disorders in Adolescence
Interactions of the amygdala, frontal cortex, and hippocampus, key structures in the corticolimbic system, play an important role in forming...
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The Develo** Brain as a Target for Experimental Treatments in Modeling Pathological Processes
This review addresses approaches to modeling impairments to brain function assessed in adulthood by targeted treatments during the perinatal period....
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Applications of Developmental Psychopathology
Developmental psychopathology studies the basic mechanisms, including not only biological factors but also environmental and social factors that may...
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Breast may not always be best: moderation of effects of postnatal depression by breastfeeding and infant sex
BackgroundThere is good evidence that female infants are particularly vulnerable to poor emotional outcomes following in utero glucocorticoid...
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Epigenetics of prenatal stress in humans: the current research landscape
Fetal exposure to prenatal stress can have significant consequences on short- and long-term health. Epigenetic mechanisms, especially DNA methylation...
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Anti-Inflammatory Therapy as a Promising Target in Neuropsychiatric Disorders
This chapter analyzes the therapeutic potential of current anti-inflammatory drugs in treating psychiatric diseases from a neuro-immunological...
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Psychological Treatment for Depressive Disorder
Depression is highly prevalent and causes unnecessary human suffering and economic loss. Therefore, its treatment and prevention are of utmost...
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Cannabis and synaptic reprogramming of the develo** brain
Recent years have been transformational in regard to the perception of the health risks and benefits of cannabis with increased acceptance of use....
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Different Phases of Schizophrenia Patients: From the Psychological Perspective
The primary purpose of this chapter is to review current clinical staging information in schizophrenia spectrum disorders. In the last two decades,...
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Assessment of the Initial Period of Schizotypal Disorder in Childhood
Objectives . To establish the developmental features, family history, social adaptation, and structure of early psychopathological disorders in...
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Psychotic Disorders (“Schizophrenia”)
After reading the chapter, the reader should be able to name the symptoms of schizophrenia as well as its treatment options and to classify different...
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The Neurotrophic, Neuroprotective, Mitogenic, Antioxidant, and Antiapoptotic Properties of Vasopressin
The vasopressinergic system is involved in the regulation of numerous physiological functions. This review focuses on the less well studied roles of...