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Effect of Curcumin on Cognitive Behavior and Pathological Characteristics of the Hippocampus in Mice with Inherent Alzheimer’s Disease
This study examined the effect of curcumin on pathological manifestations and clearance of amyloid β peptide (Aβ) in the hippocampus of 8-month-old...
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Pathological and Physiological High-frequency Oscillations on Electroencephalography in Patients with Epilepsy
High-frequency oscillations (HFOs) encompass ripples (80 Hz–200 Hz) and fast ripples (200 Hz–600 Hz), serving as a promising biomarker for localizing...
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Epidemiological, clinical, and pathological characteristics of invasive breast cancer in Bedouin and Jewish women in southern Israel: a retrospective comparative study
BackgroundInvasive breast cancer (IBC) is a leading cause of cancer-related death among women in Israel, regardless of ethnicity. This study compared...
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MMP-11 expression in early luminal breast cancer: associations with clinical, MRI, pathological characteristics, and disease-free survival
BackgroundEarly hormone-positive breast cancers typically have favorable outcomes, yet long-term surveillance is crucial due to the risk of late...
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Aluminum-Induced AD-Like Pathological Features
Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease characterized by neural aberrations in regions associated with higher...
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Changes in microstructural similarity of hippocampal subfield circuits in pathological cognitive aging
The hippocampal networks support multiple cognitive functions and may have biological roles and functions in pathological cognitive aging (PCA) and...
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Evaluation of pathological response to neoadjuvant chemotherapy in locally advanced cervical cancer
Neoadjuvant chemotherapy (NACT) is a viable therapeutic option for women diagnosed locally advanced cervical cancer (LACC). However, the factors...
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AQP4 is an Emerging Regulator of Pathological Pain: A Narrative Review
Pathological pain presents significant challenges in clinical practice and research. Aquaporin-4 (AQP4), which is primarily found in astrocytes, is...
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Analysis of related factors for pathological upgrading of cervical biopsy from CIN3 to cancer after conical resection
BackgroundTo investigate related factors for postoperative pathological upgrading of cervical biopsy to cervical cancer (CC) in patients with...
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The viral distribution and pathological characteristics of BALB/c mice infected with highly pathogenic Influenza H7N9 virus
BackgroundThe highly pathogenic Influenza H7N9 virus is believed to cause multiple organ infections. However, there have been few systematic animal...
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Pathological insights from amyotrophic lateral sclerosis animal models: comparisons, limitations, and challenges
In order to dissect amyotrophic lateral sclerosis (ALS), a multigenic, multifactorial, and progressive neurodegenerative disease with heterogeneous...
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Minimal residual disease profiling predicts pathological complete response in esophageal squamous cell carcinoma
Accurate presurgical prediction of pathological complete response (pCR) can guide treatment decisions, potentially avoiding unnecessary surgeries and...
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Scabies: Immunopathogenesis and pathological changes
Scabies is an itchy skin disease caused by the burrowing mite Sarcoptes scabiei . During their lifespan, the female mites invade the stratum corneum...
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Expressional variations of Kaiso: an association with pathological characteristics and field cancerization of OSCC
BackgroundA group of genetically altered cells that have not transformed into a clinical or histologically identifiable state of malignancy but...
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Hypoxia-induced AFAP1L1 regulates pathological neovascularization via the YAP-DLL4-NOTCH axis
BackgroundPathological neovascularization plays a pivotal role in the onset and progression of tumors and neovascular eye diseases. Despite notable...
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Pathological angiogenesis: mechanisms and therapeutic strategies
In multicellular organisms, angiogenesis, the formation of new blood vessels from pre-existing ones, is an essential process for growth and...
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Development of an Interpretable Deep Learning Model for Pathological Tumor Response Assessment After Neoadjuvant Therapy
BackgroundNeoadjuvant therapy followed by surgery has become the standard of care for locally advanced esophageal squamous cell carcinoma (ESCC) and...
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PB-LNet: a model for predicting pathological subtypes of pulmonary nodules on CT images
ObjectiveTo investigate the correlation between CT imaging features and pathological subtypes of pulmonary nodules and construct a prediction model...
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Physiological and pathological effects of phase separation in the central nervous system
Phase separation, also known as biomolecule condensate, participates in physiological processes such as transcriptional regulation, signal...
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Concurrent clinical and pathological response predicts favorable prognosis of patients with gastric cancer after neoadjuvant therapy: a real-world study
BackgroundResponse of locally advanced gastric cancer (LAGC) to neoadjuvant therapy (NAT) may be associated with prognosis, but which of the clinical...
