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Showing 1-20 of 173 results

  1. Negative serum (1,3) -β-D-glucan has a low power to exclude Pneumocystis jirovecii pneumonia (PJP) in HIV-uninfected patients with positive qPCR

    Objective

    The current study evaluated the diagnostic performance of serum (1,3)-beta-D Glucan (BDG) in differentiating PJP from P. jirovecii -colonizat...

    Yuan Huang, Jie Yi, ... Yong-zhe Li in Annals of Clinical Microbiology and Antimicrobials
    Article Open access 20 November 2023

  2. Successful treatment of a kidney transplant patient with COVID-19 and late-onset Pneumocystis jirovecii pneumonia

    Background

    Solid transplant patients are susceptible to Pneumocystis jirovecii pneumonia (PJP). While the vast majority of PJP cases occur within the...

    **g Peng, Ming Ni, ... Hong Bing Yu in Annals of Clinical Microbiology and Antimicrobials
    Article Open access 15 December 2021

  3. Epidemiology, mortality and effectiveness of prophylaxis for Pneumocystis jiroveci pneumonia among rheumatic patients: a territory-wide study

    Background

    Pneumocystis jiroveci pneumonia (PJP) is an opportunistic infection affecting immunocompromised individuals. However, evidence regarding...

    Shirley Chiu Wai Chan, Ho Yin Chung, ... Philip Hei Li in Annals of Clinical Microbiology and Antimicrobials
    Article Open access 11 November 2021

  4. Outcomes and factors contributing to poor prognosis of Pneumocystis jirovecii pneumonia in HIV-negative patients: a cross-sectional retrospective study in a Chinese single center

    Pneumocystis jirovecii pneumonia (PJP) is a life-threatening opportunistic infection mainly occurring in immunocompromised patients. Almost half of...

    Ju Zhang, **ngcheng Sun, ... Ti Zhang in European Journal of Clinical Microbiology & Infectious Diseases
    Article 01 November 2022

  5. Application of metagenomic next-generation sequencing in the diagnosis and treatment guidance of Pneumocystis jirovecii pneumonia in renal transplant recipients

    Pneumocystis jirovecii  pneumonia (PJP) is difficult to be diagnosed, so this study explored if PJP could be diagnosed by metagenomic next-generation...

    Feng Zhang, Jia Chen, ... Qiquan Wan in European Journal of Clinical Microbiology & Infectious Diseases
    Article 21 April 2021

  6. Pneumocystis jirovecii with high probability detected in bronchoalveolar lavage fluid of chemotherapy-related interstitial pneumonia in patients with lymphoma using metagenomic next-generation sequencing technology

    Background

    Previous studies achieved low microbial detection rates in lymphoma patients with interstitial pneumonia (IP) after chemotherapy. However,...

    Dian **, **g Le, ... Wenxiu Shu in Infectious Agents and Cancer
    Article Open access 06 December 2023

  8. Infectious Complications Predict Premature CD8+ T-cell Senescence in CD40 Ligand-Deficient Patients

    Purpose

    CD40 ligand (CD40L)-deficient patients display increased susceptibilities to infections that can be mitigated with effective prophylactic...

    Junghee J. Shin, Jason Catanzaro, ... Insoo Kang in Journal of Clinical Immunology
    Article 26 January 2021

  9. Monitoring, prophylaxis, and treatment of infections in patients with MM receiving bispecific antibody therapy: consensus recommendations from an expert panel

    Bispecific antibodies (BsAbs) are emerging as an important novel class of immunotherapeutic agents for the treatment of multiple myeloma (MM), and...

    Noopur Raje, Kenneth Anderson, ... Maria-Victoria Mateos in Blood Cancer Journal
    Article Open access 01 August 2023

  10. Teclistamab in relapsed refractory multiple myeloma: multi-institutional real-world study

    The objective of our study was to report real-world data on the safety and efficacy of standard-of-care teclistamab in patients with...

    Meera Mohan, Jorge Monge, ... Rajshekhar Chakraborty in Blood Cancer Journal
    Article Open access 05 March 2024

  11. AIOLOS-Associated Inborn Errors of Immunity

    AIOLOS, encoded by the IKZF3 gene, belongs to the Ikaros zinc finger transcription factor family and plays a pivotal role in regulating lymphocyte...

    Motoi Yamashita, Tomohiro Morio in Journal of Clinical Immunology
    Article Open access 22 May 2024

  12. Immune responses to human fungal pathogens and therapeutic prospects

    Pathogenic fungi have emerged as significant causes of infectious morbidity and death in patients with acquired immunodeficiency conditions such as...

    Michail S. Lionakis, Rebecca A. Drummond, Tobias M. Hohl in Nature Reviews Immunology
    Article 04 January 2023

  13. Novel Compound Heterozygous ZAP70 R37G A507T Mutations in Infant with Severe Immunodeficiency

    Zeta-chain associated protein kinase 70 kDa (ZAP70) combined immunodeficiency (CID) is an autosomal recessive severe immunodeficiency that is...

    Nathalia Benavides, Jason C. White, ... Claudio G. Giraudo in Journal of Clinical Immunology
    Article 22 December 2023

  14. Clinical and Genetic Characterization of Patients with Artemis Deficiency in Japan

    Purpose

    Artemis is an exonuclease essential for V(D)J recombination and repair of DNA double-stranded breaks. Pathogenic variants in DCLRE1C encoding...

    Kento Inoue, Satoshi Miyamoto, ... Hirokazu Kanegane in Journal of Clinical Immunology
    Article 16 November 2022

  15. Clinical Features and Genetic Analysis of Taiwanese Primary Immunodeficiency Patients with Prolonged Diarrhea and Monogenetic Inflammatory Bowel Disease

    Purpose

    Diarrhea lasting longer than 14 days which fails to respond to conventional management is defined as severe and protracted diarrhea and might...

    Wen-I. Lee, Chien-Chang Chen, ... **g-Long Huang in Journal of Clinical Immunology
    Article 19 May 2023

  17. Models of Cochlea Used in Cochlear Implant Research: A Review

    As the first clinically translated machine-neural interface, cochlear implants (CI) have demonstrated much success in providing hearing to those with...

    Filip Hrncirik, Iwan Roberts, ... Manohar Bance in Annals of Biomedical Engineering
    Article Open access 22 April 2023

  19. Diagnosis and Management of Immune-Related Adverse Events of Immune Checkpoint Inhibitor Therapy

    The landscape of cancer therapy has undergone a profound transformation in the last decade, shifting from traditional cytotoxic chemotherapy to the...
    Casey Fazer-Posorske, Lisa Kottschade, Anna Schwecke in The Basics of Cancer Immunotherapy
    Chapter 2024

  20. The 2022 Update of IUIS Phenotypical Classification for Human Inborn Errors of Immunity

    The International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) reports here the 2022 updated...

    Aziz Bousfiha, Abderrahmane Moundir, ... Isabelle Meyts in Journal of Clinical Immunology
    Article 06 October 2022
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